(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Knotty
Definition:
(superl.) Full of knots; knotted; having many knots; as, knotty timber; a knotty rope.
(superl.) Hard; rugged; as, a knotty head.
(superl.) Difficult; intricate; perplexed.
Example Sentences:
(1) Andrew Romano, Newsweek How would these eloquent know-it-alls – these brainiacs bent on "speaking truth to stupid" – untangle the knotty threads of information that make actual breaking news so difficult to sort out?
(2) It originally quoted Kathryn Bigelow as saying "naughty subjects" rather than "knotty subjects"
(3) For example, 1 group, "knotty amacrine cells," has small cell bodies and a profusion of small, varicose, intertwined processes that span up to 30 microns and are essentially monostratified, but each of the 3 types ends in different strata.
(4) He has friendly, wide-set eyes, a burst of knotty dreadlocks and a gnarled scar just below his jaw, from when he fell from a low wire as a child and impaled himself on the protruding end of a metal coil.
(5) She was a sane voice that could be relied upon to help them make sense of the knotty complications of their personal, sexual lives.
(6) Eight cases were reported in order to elucidate the important role of electron microscopy (EM) played in diagnosis of knotty tumors.
(7) What do you think they can buy for that?” Kasich also raised the other knotty problem that is causing divisions within the Republican party: preexisting conditions.
(8) The A1 cells are small axonless neurons with knotty and dense dendritic trees.
(9) This is potentially a knotty problem, but a few points seem to suggest that Wales's concerns are overdone.
(10) Bloomberg Associates, as he is calling his private consultancy, will be what the New York Times has called an “urban SWAT team” that will be called in by struggling cities to help solve their knotty problems absolutely free of charge.
(11) Updated at 9.37pm BST 8.47pm BST A novel Peace Prize idea This is interesting - European leaders have apparently been considering the knotty problem of who should pick up the Nobel Peace Prize in December.
(12) There is a knotty ethical problem underlying such arguments.
(13) Subjects ranged from the English civil war in The Staffordshire Rebels (1965) and local railways in The Knotty (1966) to the audience's second world war memories in Hands Up!
(14) This knotty and discomforting genealogy that binds Englishness to empire and slavery and their fractious legacies of racism and inequality seems to be too thought-provoking for Gove's deeply conservative vision of English literature.
(15) But it would help his cause, the lawyer argued, by addressing several of the knotty issues related to his future.
(16) Every time a party has looked at this problem, it’s been too knotty to unpick and it has given up.
(17) What distinguishes this recession from those we have seen before is one particularly knotty fact: unemployment has increased a good deal more than employment has fallen.
(18) Only a better understanding of their pathogenesis, and of how the glomerulus normally retains plasma protein, will solve this knotty problem.
(19) The prospect of Erdoğan unbound suggests a number of other knotty problems may become more intractable.
(20) Canary Wharf – modernist, faceless, towering – houses the mighty investment banks; the City – quirky, crowded, knotty, historic – has the brokers, insurers and ancillary services; Mayfair – discreet, stylish, cosmopolitan – is home to the hedge funds and private equity companies.