(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Perplex
Definition:
(a.) To involve; to entangle; to make intricate or complicated, and difficult to be unraveled or understood; as, to perplex one with doubts.
(a.) To embarrass; to puzzle; to distract; to bewilder; to confuse; to trouble with ambiguity, suspense, or anxiety.
(a.) To plague; to vex; to tormen.
(a.) Intricate; difficult.
Example Sentences:
(1) Perplexed, from being absorbed into some undateable future world governed by an advanced technology whose capacities have to be learned as one reads.
(2) The sergeant, listening in, was perplexed: "We obviously have, because I can hear you on the radio.
(3) Whether FcR-mediated signaling and receptor-mediated signaling involved in NK activity share specific biochemical intermediates is not known, but the involvement of tyrosine kinase function in the latter means of cytotoxicity may provide novel avenues for understanding the biochemical basis of this perplexing cellular function.
(4) The arteriogram correctly localized the precise site of hemorrhage in this perplexing case, and a complex surgical problem was simplified.
(5) The trauma-ready practice must also be cognizant of the some-times perplexing legal and insurance issues with regard to preventing and treating sport-related injuries.
(6) According to Lukyanov, the Kremlin is “perplexed” by Trump because it’s not clear what his priorities are nor whether he can work with Congress to achieve them.
(7) While treatment of a young woman with a dysgerminoma of 1 ovary is a matter of perplexity, we believe that a unilateral operation should be limited to those women who desire above all earthly things to retain their childbearing capacity.
(8) The most perplexing issues in pediatric dentistry today are related to the management of patients.
(9) "It is perplexing and preposterous to hear human rights complaints from the US, where torture and kidnapping are legal in the 21st century."
(10) It was a wretched goal to concede and the unfortunate truth for Mignolet is that moment reminded us why many Liverpool supporters are perplexed he has been awarded a new five-year contract.
(11) Instead, when we meet her at the beginning of the series, Nyborg is more concerned with moving house – presumably supplying viewers with shots of a variety of stylish new light fittings and perplexing floor plans to obsess over – than a political party with which she is increasingly disillusioned.
(12) I was [looks perplexed]: ‘Where’s the fabulous Madonna ?’ But it was still deeply interesting just to shake this tiny little hand, and say ‘You’re real’, because in the 80s, these people lived on plinths, they never came down to Earth.” This encounter made Patterson realise that celebrity per se didn’t exist.
(13) The implementation of library orientation and bibliographic instruction in health sciences centers presents some interesting as well as perplexing problems.
(14) It is now shown that the perplexity may be due to the possibility that the coenzyme (NAD) required for UDPG-D activity, may be acting as a substrate for a second dehydrogenase, namely xanthine dehydrogenase, which may utilize NAD as its substrate.
(15) Management of the patient with tinnitus is an extremely perplexing problem.
(16) Paul Salveson, author of a new book on the future of the railways, Railpolitik , is equally perplexed.
(17) Prematurity is one of the most perplexing problems in perinatal care.
(18) If chemical weapons were used, the timing of the attack is perplexing, the inspector said.
(19) Perplexing findings of cortical somatosensory evoked potentials (SEP's) for determining the central sulcus during a craniotomy are reported in a case of brain tumor.
(20) As cellular and molecular approaches combine with physiologic techniques, new information will be available to address the clinical issues of luteal dysfunction which perplex us all.