(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Scarce
Definition:
(superl.) Not plentiful or abundant; in small quantity in proportion to the demand; not easily to be procured; rare; uncommon.
(superl.) Scantily supplied (with); deficient (in); -- with of.
(superl.) Sparing; frugal; parsimonious; stingy.
(adv.) Alt. of Scarcely
Example Sentences:
(1) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(2) However, H2-blocking agents, such as cimetidine and ranitidine, given either intravenously or intraspinally had a scarcely measurable effect on the spinal reflex.
(3) But even before the reforms, half of the women coming to refuges were being turned away, so beds were already scarce.
(4) Three motives are found for evaluating the quality of human life: allocation of scarce medical resources, facilitating clinical decision making, and assisting patients towards autonomous decision making.
(5) The glory lay in the defiance, although the outcome of the tie scarcely looks promising for Arsenal when the return at Camp Nou next Tuesday is borne in mind.
(6) A fat emulsion when injected into tissue is scarcely taken up by the blood vascular system but is retained within the tissue over a relatively extended period, and is distributed slowly into the surrounding tissues and to the regional lymph nodes.
(7) To date, these new and interesting capabilities have scarcely been exploited.
(8) Casadevall said the pressures to commit fraud came from many sources - not least the competition for scarce funding for research.
(9) 1: Good news It's been a scarce commodity throughout the Osborne chancellorship, but he will have a decent amount of it to dish round the chamber – notably lower inflation and higher growth than was being forecast a short while ago.
(10) Necrotic cells were infiltrated with numerous red blood cells and scarce inflammatory cells.
(11) Lactate strongly inhibited glucose oxidation through the pyruvate dehydrogenase-catalyzed reaction and the tricarboxylic acid cycle while scarcely affecting glucose utilization by the pentose phosphate pathway.
(12) Scarce economic resources make cost-benefit assessment of employee training programs an important issue.
(13) Virtually, all unsuccessful cases of mycoses treated with some of the recently exploited antifungal drugs, albeit scarce to date, would obviously be attributable to the occurrence of secondary resistance.
(14) In the strictly anaerobic acetoin-utilizing bacteria P. carbinolicus, Pelobacter venetianus, Pelobacter acetylenicus, Pelobacter propionicus, Acetobacterium carbinolicum, and Clostridium magnum, the enzymes Ao:DCPIP OR, DHLTA, and DHLDH were induced during growth on acetoin, whereas they were absent or scarcely present in cells grown on a nonacetoinogenic substrate.
(15) The situation is more challenging for developing countries, which must add new priorities to the scarce resources of their health and social programs when they still have to deal with the problems of their younger population.
(16) It should be noted nevertheless that the Casale Hospital supplies a scarcely industrialized urban area, and a wide rural environment, so that resident population might be included within one of the groups partially protected by environmental and alimentary conritions against the disease.
(17) Though large numbers of young people can be an economic advantage, a combination of unfulfilled aspirations, scarce land and water, overcrowding in growing cities as well as inadequate infrastructure could lead to social tensions and political instability.
(18) Probably as a result of the failure of down-regulation, the prominent inhibition of sterol synthesis from acetate and 3-hydroxy-3-methylglutaryl-coenzyme A reductase observed in CHO cells is scarcely detectable in Monr-31 cells.
(19) The practice, and training programme for radiology in West Africa should reflect the scarce human and natural resources of West Africa, as well as the peculiar problems of the region, within the context of the acceptable pattern of health care delivery.
(20) The New Economics Foundation guessed that it could be anywhere between 3.4 and 8.3p ; 8.3 pence was so far beyond what anyone else forecast that I treated it as scarcely credible.