(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.
Dysphagia
Definition:
(n.) Alt. of Dysphagy
Example Sentences:
(1) All patients presented with severe oropharyngeal dysphagia and frequent aspiration together with pharyngooral and pharyngonasal regurgitation.
(2) Patients were divided into two groups based on etiology of dysphagia (central neurologic vs local mechanical dysfunction).
(3) The main side effect was dysphagia, which appeared to be dose related in individual patients.
(4) A patient presenting with dysphagia and weight loss was found to have a large midesophageal mass.
(5) Experience from the use of feeding plates for babies with cleft palate and from the treatment of dysphagia in patients recovering from stroke led to the design of a simple intraoral appliance.
(6) Carefull angiographic investigation can avoid misjudging the symptoms (stridor, dysphagia) and can contribute to an exact diagnosis thus preventing unnecessary operation.
(7) Complications, such as superficial ulcers, dysphagia, and strictures, were observed in 14%, 7% of emergency, and 3% of elective patients.
(8) The children (a two-year and a three-year old boy), who seemed completely healthy, sudden suffered from acute inflammation of the upper respiratory tract with dyspnea, inspiratory stridor, fever, dysphagia, and flow of saliva.
(9) A case of massive DISH in the cervical spine causing dysphagia is described.
(10) Failure to complete feeds, dysphagia, vomiting, coughing, choking and recurrent respiratory symptoms were also significantly more common in this group than in the primary anastomosis group (labeled as group A) even in the absence of stricture.
(11) Eighteen patients complained of dysphagia, but only in 12 of them did endoscopy show esophagitis.
(12) Twenty-four Bouviers with dysphagia were examined between October 1986 and October 1988.
(13) Dysphagia was progressive in all 15 and, in most cases, preceded the onset of other severe brain stem signs.
(14) However, this graft may cause dysphagia by discoordination of contractions, retrograde propulsion of a bolus, or a sustained local contraction, demonstrating the clinical problems associated with free jejunal graft reconstruction of the cervical esophagus.
(15) However, dysphagia occurred in pigs kept alive for more than a month and the main reason was malfunction of the device because of surrounding fibrosis.
(16) Records from 910 patients referred to our clinical esophageal manometry laboratory for evaluation of noncardiac chest pain between January 1983 and December 1985 were reviewed and compared with records from 251 patients referred for dysphagia.
(17) Recurrent ossifications were detected in them some years after surgery, and one of them complained of dysphagia again.
(18) This serendipitous observation antedates clinical signs and symptoms of dysphagia.
(19) The most important manometric abnormality was the feeble contractions of the pharyngeal musculature, more pronounced in patients with severe dysphagia (grade II).
(20) Six refused because of excellent relief of their dysphagia, and one was denied operation.