(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.
Problematic
Definition:
(a.) Alt. of Problematical
Example Sentences:
(1) Results show diet, self-control and parts of insulin-therapy to be problematic treatment components.
(2) Other problematic diagnoses were cancer of the head and neck and malignant fibrous histiocytoma.
(3) Various feedback techniques have been reported of value, but their superiority to suggestion and hypnosis is still problematic.
(4) Villous tumors of the duodenum are rare, but treatment may be problematic because of their association with invasive adenocarcinoma.
(5) "It causes a great deal of concern and is very problematic for social cohesion when people find they aren't provided with any preference when they are actually in the area they have lived in for a very long time," he told the Sunday Times.
(6) More problematic for Brown is that he has come to embody a government sufficiently unconvinced of its own case as to risk short-changing the armed forces at the front.
(7) The development of gallstones following this procedure, however, has become more problematic in that further opeation becomes a real necessity.
(8) The findings may be of assistance in general surgical reporting of problematic cases.
(9) The missing output of urine is an emergency case which is problematic with regard to old patients.
(10) The authors describe an approach to these problematic behaviors based upon early recognition, a clinical perspective, and administrative action.
(11) Detection of estrus in mares is problematic in that it requires the presence (or at least facsimile acoustic or tactile stimuli) or a stallion.
(12) In patients with problematic CT findings, particularly children and patients with allergies to contrast media, suprasternal sonography can provide important additional information.
(13) CVVH is suited to individualization of ultrafiltration and solute clearance in patients with acute renal failure and volume overload, specifically when there is impaired cardiovascular function or where arterial access is problematic.
(14) Patients with bilateral Wilms' tumor who have local recurrence after undergoing maximum-dose multitechnique therapy are problematic.
(15) As he rose to speak, a BBC spokesman reiterated management's opposition to revealing stars' salaries, telling journalists: "We've been consistent in our view that revealing contractual details of BBC talent is problematic for reasons of confidentiality."
(16) The second, or 'discrepancy model', suggests that the adoption of modern behaviors is problematic only when the individual has limited access to economic resources.
(17) It would be hugely problematic for Perry if any clear evidence were to emerge that he stopped the funding because he did not want a public integrity unit, especially one led by a Democrat, probing too closely into alleged improprieties .
(18) It is reported about 2 patients in whom the decision on electroconvulsive therapy was rendered more problematic by proven organic defects of the brain or a seizure disease.
(19) #p0rn What is genuinely concerning is that Meow has an option to hide a person's age, which could be very problematic in the wrong hands.
(20) Documentation of bioequivalence of topical products has been problematic, and current methods are being re-evaluated by the Food and Drug Administration.