(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.
Relieve
Definition:
(v. t.) To lift up; to raise again, as one who has fallen; to cause to rise.
(v. t.) To cause to seem to rise; to put in relief; to give prominence or conspicuousness to; to set off by contrast.
(v. t.) To raise up something in; to introduce a contrast or variety into; to remove the monotony or sameness of.
(v. t.) To raise or remove, as anything which depresses, weighs down, or crushes; to render less burdensome or afflicting; to alleviate; to abate; to mitigate; to lessen; as, to relieve pain; to relieve the wants of the poor.
(v. t.) To free, wholly or partly, from any burden, trial, evil, distress, or the like; to give ease, comfort, or consolation to; to give aid, help, or succor to; to support, strengthen, or deliver; as, to relieve a besieged town.
(v. t.) To release from a post, station, or duty; to put another in place of, or to take the place of, in the bearing of any burden, or discharge of any duty.
(v. t.) To ease of any imposition, burden, wrong, or oppression, by judicial or legislative interposition, as by the removal of a grievance, by indemnification for losses, or the like; to right.
Example Sentences:
(1) These results show that lipo-PGI2 at a very low dose would be beneficial as a treatment for relieving the clinical symptoms of chronic cerebral infarction and that lipid microspheres are a useful drug carrier for PGI2 analogue therapy.
(2) Current recommendations regarding contraception in patients with diabetes are not appropriate for the adolescent population and therefore tend to support this phenomenon rather than relieve it.
(3) In addition, the menisci increase the femorotibial contact area, thereby relieving some of the pressure.
(4) Arrhythmias were controlled without the need of drug therapy in 2 cases and the clinical symptoms were relieved in 1 case after shocks.
(5) Ultrasonic fragmentation through the pars plana is a quick and easy method for relieving the condition.
(6) The following examinations could be proposed: in high risk cases determined before pregnancy, a chorionic villus sampling should be done between the 9th and 11th weeks of gestation; in low risk cases such as advanced maternal age, a first trimester chorionic villus sampling or a second trimester amniocentesis could be chosen; in the case of Down's syndrome, warning signs, for example ultrasonographic or biological parameters, a second trimester placental biopsy to relieve the parents' anxiety; in high risk cases such as ultrasonographic malformations, late placental biopsy or cordocentesis.
(7) Pain relieved by antacids, age above 40 years, previous peptic ulcer disease, male sex, symptoms provoked by berries, and night pain relieved by antacids and food were found to predict organic dyspepsia with a sensitivity and specificity of approximately 70%, when applied on the observed material.
(8) In spite of this fundamental disagreement, they were both relieved that President Obama has suspended his plan to launch missiles against Syria .
(9) The procedure appears to relieve papilledema by filtering small quantities of cerebrospinal fluid into the orbit.
(10) In 2 cases, sublingual nitroglycerin failed to completely relieve the spasm.
(11) Euthanasia – killing someone painlessly, usually to relieve suffering – is also illegal.
(12) Symptoms were relieved following posterior decompression and fusion from L5 to S1.
(13) The austerity programmes administered by western governments in the wake of the 2008 global financial crisis were, of course, intended as a remedy, a tough but necessary course of treatment to relieve the symptoms of debts and deficits and to cure recession.
(14) He had no business getting to that ball ahead of the full-back, who will be mightily relieved.
(15) Following this combination procedure the patients were relieved completely of obstructive jaundice and right upper quadrant pain, leaving only small trocar insertion scars made during the short course of hospitalization.
(16) The medicinal therapy of osteoarthritis is based on the use of analgesics, NSAIDs and corticosteroids to relieve pain and inflammation.
(17) The characteristic signs and symptoms represent the triad of a pulsatile mass in the upper part of the abdomen, intermittent hemorrhage in the upper part of the gastrointestinal tract and severe epigastralgia not relieved by antacids.
(18) Examination of the inhibitory effect of ATP using oligo(dA)12-18 as well as activated DNA as primers revealed that (a) ATP inhibition is not due to its addition onto a 3'-OH primer terminus ad judged by the lack of incorporation of labeled ATP, although under similar conditions incorporation of GTP can be demonstrated, (b) a consistent degree of inhibition was noted independent of primer or enzyme concentration; (c) addition of ATP to an ongoing reaction promptly reduces the rate of polymerization; (d) kinetic studies indicate a competitive (with respect to substrate deoxy triphosphate) pattern of inhibition; (e) addition of excess deoxyribotriphosphate promptly relieves the inhibition.
(19) The results suggest that the pantethine relieves the effect of dosed AL on the drug-metabolizing system in rat liver.
(20) "Richard only finished the music today," said Croall, who seemed deeply relieved that he'd made the deadline on Saturday.