(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.
Steadfastness
Definition:
(n.) The quality or state of being steadfast; firmness; fixedness; constancy.
Example Sentences:
(1) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(2) "Although she was always a steadfast critic of apartheid, she had a much better grasp of the complexities and geostrategic realities of South Africa than many of her contemporaries," he said.
(3) One of those convictions was his steadfast and passionate belief in the importance of the US-Saudi relationship as a force for stability and security in the Middle East and beyond.
(4) His remarks came as the Republican leadership in the US Senate remained steadfast in its opposition to filling the supreme court vacancy under Obama’s watch.
(5) In a statement, a spokesperson said that the Obama emphasised that the US “remains steadfast in [its] commitment to the security of Israel .” Netanyahu told Obama that Israel “vehemently opposes” the framework deal .
(6) But the county authorities, along with Montana's state election officials, have steadfastly refused to grant the request, offering a panoply of excuses, many of them contradictory.
(7) The present review is first and foremost a tribute to Monroe Eaton and his colleagues for their trail-blazing discovery of a major cause of the atypical pneumonia syndrome and their steadfast vision of its importance.
(8) By being steadfast in our values we can impel Russia to rethink its ambitions; by being mild we can encourage their cruellest actions.
(9) He argues that the previous EULA was more restrictive, but is steadfast that "ranks" and "kits" are ways to pay for progress and therefore not allowed – whatever they may (or may not) add to the experience.
(10) Why not?” May on Sunday told Fabian Picardo, the chief minister of Gibraltar, that the UK remained “steadfastly committed to our support for Gibraltar, its people and its economy”, according to the details of a telephone conversation released by Downing Street.
(11) I have also never been more encouraged by your dedication and steadfast commitment to our future.
(12) "Secretary Kerry has a proud record of over three decades of steadfast support for Israel's security and wellbeing, including staunch opposition to boycotts," Psaki said in a statement.
(13) "Donor agencies were given highly credible first-hand accounts of serious human rights violations during their field investigation, and they have chosen to steadfastly ignore these accounts," says the report, written by Will Hurd, an NGO worker who served as a translator for a team of DfID and USAid officials on a visit to the region in January 2012.
(14) Confronted with steadfast mission requirements, increasing demands for dental services, and a reduction of professional staff, the Corps has responded to challenge with the implementation of an alternative to the limitations of established and traditional concepts of practice.
(15) The prime minister, Tony Abbott, has steadfastly refused to do so, citing the Coalition’s long-held refusal to talk about operational “on-water” matters.
(16) Though framed by record high temperatures and an increasing number of extreme weather events, the Paris talks are already beset by the same problems that repeatedly dog climate change negotiations: the richest countries steadfastly refuse to meet legal commitments and shoulder their share of responsibility , preferring to uphold the desires of all-powerful corporate lobbies.
(17) But where some traditions were broken, others remain steadfastly in place.
(18) Her commitment went beyond this role and she remained steadfast to social work and the people it serves.
(19) Is steadfastly denying her son so admirable, when other parents remortgage and raid pensions to help their children on their way?
(20) The mayor has steadfastly refused to step down since reports emerged of a video of him smoking crack.