(n.) The state of being difficult, or hard to do; hardness; arduousness; -- opposed to easiness or facility; as, the difficulty of a task or enterprise; a work of difficulty.
(n.) Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
(n.) A controversy; a falling out; a disagreement; an objection; a cavil.
(n.) Embarrassment of affairs, especially financial affairs; -- usually in the plural; as, to be in difficulties.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(3) Epidemiological studies on low risks involve a number of major methodological difficulties.
(4) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(5) Reasons for non-acceptance do not indicate any major difficulties in the employment of such staff in general practice, at least as far as the patients are concerned.
(6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
(7) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(8) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(9) A control experiment demonstrated that changes in general arousal could not account for the effects of task difficulty on neuronal responses.
(10) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
(11) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(12) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(13) Marked pain and great difficulty in introducing the apparatus made its use limited in respectively 15% and 14.5% of cases.
(14) The tasks which appeared to present the most difficulties for the patients were written spelling, pragmatic processing tasks like sentence disambiguation and proverb interpretation.
(15) In favorable cases, tRNA-DNA hybrids of length about 80 nucleotide pairs can be recognized (although with difficulty).
(16) The patient with the right posterior lesion could not recognize handwriting, was prosopagnosic and topographagnosic, but had no difficulty in reading, lipreading, or in recognizing stylized drawings.
(17) A review of the literature summarises the difficulties of diagnosis.
(18) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(19) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(20) While mindful of the potential difficulties which attend its introduction into the treatment situation there is an attempt to balance this position through a consideration of the appropriate conditions and modes of operation under which a humor-enriched approach may be efficacious.
Trouble
Definition:
(v. t.) A fault or interruption in a stratum.
(v. t.) To put into confused motion; to disturb; to agitate.
(v. t.) To disturb; to perplex; to afflict; to distress; to grieve; to fret; to annoy; to vex.
(v. t.) To give occasion for labor to; -- used in polite phraseology; as, I will not trouble you to deliver the letter.
(a.) Troubled; dark; gloomy.
(v. t.) The state of being troubled; disturbance; agitation; uneasiness; vexation; calamity.
(v. t.) That which gives disturbance, annoyance, or vexation; that which afflicts.
Example Sentences:
(1) The patient was a forty-five-year-old female who had been troubled by obstinate Raynaud's phenomenon for ten years before the definite diagnosis of pulmonary hypertension was made.
(2) Based on a large, ongoing empirical research effort to determine factors associated with the successful community adjustment of troubled adolescents leaving residential treatment, this paper focuses on multiple indicators of success measured at multiple points of time in the treatment process.
(3) "The disrespect embodied in these apparent mass violations of the law is part of a larger pattern of seeming indifference to the constitution that is deeply troubling to millions of Americans in both political parties," he said.
(4) Its current troubles are in part due to the fact that Colt lost out on the M4 US army contract to FN Herstal in 2013.
(5) FC Terek Grozny, the newly energised team based in the troubled Caucasus republic of Chechnya , is hoping a slew of high-profile international acquisitions will help it make waves in the Russian premier league, which kicked off last weekend.
(6) The writer Palesa Morudu told me that she sees, in the South African pride that "we did it", a troubling anxiety that we can't: "Why are we celebrating that we built stadiums on time?
(7) They can genuinely believe their partner provoked them to commit the abuse, just so they could get them in trouble.
(8) Here's something else you've worked out: Anthony's name is made up, in order to stop my interviewee from getting in trouble with his employer, and I can't be too specific about his living arrangements.
(9) Perhaps strangely, it was the second remark that troubled me more than the possibility that humanity would be extinguished by my hand.
(10) Concerning the etio-pathogenic study, as we tried to show, the authors agree in simultaneous and contemporary appearance, between the 4th and the 6th month of the intra-uterine life of oculo-cerebro-renal troubles of Lowe's Syndrom and in the existence of a common factor, probably a genetic one.
(11) The very low number of African members is particularly troubling, because more than one third of projects take place in that region.
(12) "When people don't feel they have a reason to stay out of trouble, the consequences for communities can be devastating – as we saw last August," said Darra Singh, chair of the panel.
(13) Arvind Kejriwal, leader of a new populist political party "dedicated to improving the lot of the common man", announced on Monday that he would form a government to run the sprawling, troubled and increasingly wealthy city of 15 million people.
(14) While Brown – finally fit again after appalling knee trouble that very nearly ended his career –began a home game for the first time since January 2012, Poyet only found room in Sunderland's starting XI for five of the 14 summer signings secured by Roberto De Fanti, the club's director of football.
(15) Port Vale are in deep financial trouble and their administrators will not let him pay half the player's wages.
(16) Flying in Soyuz was “ real teamwork ” she said, adding: “Tim will have no trouble with that.” David Southwood , a senior researcher at Imperial College, and a member of the UK space agency steering board, has known Tim since he joined the European Space Agency in 2009.
(17) Last month Neil Berkett, Virgin Media's chief executive, said he was "not surprised" YouView had run into trouble, given the number of partners involved, adding that the cable company intended to "take advantage" of the delay.
(18) Britain’s troubled relationship with the EU has provided Boris Johnson with nothing but fun since he first made his name lampooning the federalist ambitions of Jacques Delors as the Daily Telegraph’s Brussels correspondent in the early 1990s .
(19) Mohammed Salama, 23, an Al Ahly ultra whose leg was broken in the stadium riot, said it became clear at half-time in the match between the two historical foes that trouble was brewing.
(20) They were compared to two groups: normal elderly subjects with no memory trouble and no attention dysfunction (12 subjects, mean age: 66) and elderly subjects with minor trouble in STM and little attention disturbance (6 subjects, mean age: 68.5).