(n.) The act of diffusing, or the state of being diffused; a spreading; extension; dissemination; circulation; dispersion.
(n.) The act of passing by osmosis through animal membranes, as in the distribution of poisons, gases, etc., through the body. Unlike absorption, diffusion may go on after death, that is, after the blood ceases to circulate.
Example Sentences:
(1) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(2) The femoral component, made of Tivanium with titanium mesh attached to it by a new process called diffusion bonding, retains superalloy fatigue strength characteristics.
(3) The diffusion of Myocamicin in the prostatic tissue of patients undergoing prostatectomy after a single oral dose of 600 mg has been studied.
(4) The preembedding method also disclosed diffuse cytosolic immunoreactivity.
(5) The clinical aspects, the modality of onset and diffusion of the lymphoma, its macroscopic and histopathological features and the different therapeutic approaches are discussed.
(6) The kidney disease was characterized by diffuse beaded deposition of rat gammaglobulin along the glomerular capillaries and proteinuria.
(7) We identified four distinct clinical patterns in the 244 patients with true positive MAI infections: (a) pulmonary nodules ("tuberculomas") indistinguishable from pulmonary neoplasms (78 patients); (b) chronic bronchitis or bronchiectasis with sputum repeatedly positive for MAI or granulomas on biopsy (58 patients, virtually all older white women); (c) cavitary lung disease and scattered pulmonary nodules mimicking M. tuberculosis infection (12 patients); (d) diffuse pulmonary infiltrations in immunocompromised hosts, primarily patients with AIDS (96 patients).
(8) Sera from three of these patients gave a precipitin band in gel diffusion tests identical to that produced by a monospecific rabbit anti-E. granulosus antigen 5 serum, when tested against whole hydatid fluid.
(9) A constellation of histologic lesions was identified in brain (diffuse meningoencephalitis with bilaterally symmetrical thalamic necrosis), liver (pericholangiohepatitis), lung (pneumonitis), and spleen (lymphoid hyperplasia); this tetrad is apparently unique to this model system.
(10) Diffuse Ga-67 uptake in the kidneys was seen due to renal involvement with this disorder.
(11) Thus, whereas CD3-associated molecules isolated from polyclonal CD3+WT31+ populations (expanded in IL 2 under the same culture conditions) appeared as diffuse bands, CD3-associated molecules isolated from CD3+WT31- populations displayed a homogeneous molecular mass.
(12) The diffuse reaction product seen in basement membranes of ganglion and nerve may also be artifact.
(13) Here we determine the position of bound ADP diffused into the recA crystal.
(14) In contrast, boundary layer diffusion is operative in the release from the matrixes prepared by compression of physical mixtures.
(15) Medium molecules have been detected by two methods, gel filtration and screening technique, in patients with diffuse purulent peritonitis and with chronic renal insufficiency.
(16) This may be because the epithelium restricts diffusion of the drug or due to the production of a non-prostanoid factor which inhibits smooth muscle responsiveness.
(17) Ten of 11 diffuse poorly differentiated lymphocytic lymphomas were composed of cells with large amounts of surface immunoglobulin, whereas only 1 of 5 diffuse well differentiated lymphocytic tumors contained such abundant surface immunoglobulin.
(18) Thirty-six lesions imaged as vascular malformations with abnormal vessels or diffusely increased activity.
(19) We therefore conclude that the protective effect displayed by solid grafts might be a local process dependent on the release of diffusible trophic agents.
(20) These results demonstrate, in living human hearts, that diffuse coronary atherosclerosis is often present when coronary angiography reveals only discrete stenoses.
Dissemination
Definition:
(n.) The act of disseminating, or the state of being disseminated; diffusion for propagation and permanence; a scattering or spreading abroad, as of ideas, beliefs, etc.
Example Sentences:
(1) Disseminated CMV infection with multiorgan involvement was evident in 7 of 9 at postmortem examination.
(2) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
(3) Evidence is presented in support of the hypothesis that fresh bat guano serves as a means of pathogenic fungi dissemination in caves.
(4) Two cases are presented of bilateral ureteral obstruction and uremia due to pressure from nodes involved in disseminated lymphoma.
(5) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
(6) On the other hand, the injection of minute quantities of endotoxin into PbAc(2)-sensitized rats invariably resulted in disseminated intravascular coagulation, apparently via a complete activation of the intrinsic pathway.
(7) Seven patients have not shown evidence of dissemination, and five are alive 1--15 years (median 9 years) after diagnosis.
(8) Calculations were made to test whether the hypothesis of a multistep dissemination of the tumour from the primary site was likely.
(9) The skin lesions resembled disseminated subacute lupus erythematosus on clinical examination, but actinic granuloma or annular elastolytic giant cell granuloma was seen in biopsy specimens of the lesions.
(10) Among 137 consecutive patients who had a sterile body site cultured for mycobacteria within 3 months of their first AIDS-defining episode of Pneumocystis carinii pneumonia, median survival was significantly shorter in those with disseminated MAC infection (107 days; 95% confidence interval [CI] 55-179) than those with negative cultures (275 days; 95% CI 230-318; P less than .01), even after controlling for age, absolute lymphocyte count, and hemoglobin concentration.
(11) Acyclovir is commonly used for suppression and treatment of recurrent genital herpes simplex virus and may be indicated for pregnant women with disseminated herpes.
(12) A more regular distribution of these mites on the animals points to the mixing of the mites population that effects the dissemination of agents.
(13) We report the first case (to our knowledge) of disseminated Phialophora parasitica infection.
(14) Myelography and cytology studies are necessary in the evaluation of all newly diagnosed patients with medulloblastoma and may also be indicated for patients with other brain tumors with a known propensity for dissemination.
(15) Splenomegaly in recipient mice suggested systemic dissemination of the local GvHR.
(16) Although the follow-up period is still short, the combined treatment of radiation and pre-radiation chemotherapy appears to be an effective treatment, and has made a major impact upon survival time in cases of disseminated esophageal carcinoma.
(17) A careful study of recurrences after operation, their localization, provides evidence for regarding that 6.9% had primary-multiple, combined, and disseminated affections.
(18) Immune complexes formed in vivo were also purified by conglutinin column from the serum of a patient with disseminated leishmaniasis.
(19) Spinal changes in 13 cases included vacuolar myelopathy (7 cases), HIV myelitis (1 case) and ganglio-radiculitis (1 cases), cytomegalovirus myelo-radiculitis (1 case) secondary spread from a lymphoma (1 case) and spinal infarcts due to disseminated intravascular coagulation (1 case).
(20) This cytotoxic regimen, which has been well tolerated, may prove valuable in the management of disseminated carcinoid tumours.