What's the difference between digestion and proteolysis?

Digestion


Definition:

  • (n.) The act or process of digesting; reduction to order; classification; thoughtful consideration.
  • (n.) The conversion of food, in the stomach and intestines, into soluble and diffusible products, capable of being absorbed by the blood.
  • (n.) Generation of pus; suppuration.

Example Sentences:

  • (1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
  • (2) The neurologic or digestive signs were present in 12% of the children.
  • (3) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
  • (4) To determine whether or not the glycan moieties in hTPO play a role in the disease-associated epitopes in Hashimoto's thyroiditis, radiolabeled recombinant hTPO was immunoprecipitated after digestion with N-glycanase.
  • (5) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
  • (6) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
  • (7) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
  • (8) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
  • (9) High radioactivities were observed in the digestive organs, mesenteric lymphnodes, liver, pancreas, urinary bladder, fat tissue, kidney and spleen after oral administration to rats.
  • (10) Digestion is initiated in the gastric region by secretion of acid and pepsin; however, diversity of digestive enzymes is highest in the post-gastric alimentary canal with the greatest proteolytic activity in the spiral valve.
  • (11) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
  • (12) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
  • (13) The effect of dietary fibre digestion in the human gut on its ability to alter bowel habit and impair mineral absorption has been investigated using the technique of metablic balance.
  • (14) Between the 24th and 29th day mature daughter sporocysts with fully developed cercariae ready to emerge, or already emerged, could be seen in the digestive gland of the snail.
  • (15) Amino acid analysis indicated a significant number of serine amino acids: N-terminal sequence data demonstrated a high level of homology; and trypsin digestion followed by reversed-phase HPLC indicated the possibility of multiple phosphorylation sites.
  • (16) Radio-immunoprecipitation and partial proteolytic digest mapping showed that the monoclonal antibodies each recognized a unique epitope.
  • (17) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
  • (18) Since the gastric motor pattern consisted of two major subpatterns, digestive and interdigestive motor activity, motilin was tested for its motor stimulating activity in both states.
  • (19) The product (AF-AGIIb-1) of digestion of AGIIb-1 with exo-alpha-L-arabinofuranosidase had markedly increased anti-complementary activity, as did that (AF-N-I) of N-I.
  • (20) The digestion products were separated by electrophoresis in agarose gels.

Proteolysis


Definition:

  • (n.) The digestion or dissolving of proteid matter by proteolytic ferments.

Example Sentences:

  • (1) This indicated that proteolysis at Lys1313-Glu also proceeded in native alpha 2M.
  • (2) By contrast, at 100 microM insulin concentration, both enhancers accelerated insulin proteolysis.
  • (3) It was found that these Hageman factor fragments promoted rapid proteolysis of one-chain factor VII to a more active two-chain form.
  • (4) Lengthy digestions with both proteases produced fragments of the receptor which appeared to be resistant to further proteolysis.
  • (5) By a mechanism as yet unknown, but most likely a limited proteolysis, the secreted inhibitor is liberated from the high molecular weight precursor.
  • (6) Phosphorylation or partial proteolysis of the kinase, which are known to activate phosphorylase conversion, also activate the ATPase activity.
  • (7) The effect of controlled proteolysis of intrinsic proteins was also tested.
  • (8) The disc-gel patterns of the 8 m urea-soluble proteins showed that C. perfringens caused extensive proteolysis in pig muscle and a lesser extent of proteolysis in rabbit muscle.
  • (9) A23187, KC1, sucrose, and 8-(diethylamino)octyl-3,4, 5-trimethoxybenzoate hydrochloride increase proteolysis while tetracaine, verapamil, and low extracellular calcium caused significant decreases.
  • (10) Two main polypeptides, Mr about 27,000 and 21,000, were protected against pepsin proteolysis when a mixture consisting of asolectin vesicles and 125I-labeled tetanus toxin was subjected to a pH drop from 7.2 to 3.0.
  • (11) This altered region spans the normal site of autocatalytic proteolysis that occurs at the same time as (enzymatic) activation of prochymosin at acidic pH.
  • (12) The polypeptides that remain associated with the membranous structure after proteolysis were detected by sodium dodecyl sulfate gel electrophoresis.
  • (13) This system should allow studies on the modulation of proteolysis in intact lung under defined conditions.
  • (14) Proteolysis at the latter sequence has not been previously reported in intact secretory granules.
  • (15) Since the HPV-16 E6-promoted degradation involves the ubiquitin-dependent proteolysis pathway, specific mutations were made in the amino terminus of p53 to examine whether the E6 targeted degradation involved the N-end rule pathway.
  • (16) Proteolysis studies of purified VIII:C using thrombin and activated protein C have suggested that the 92,000- and 80,000 (or 72,000)-mol wt polypeptides comprise activated VIII:C. We have now used seven monoclonal antibodies raised against purified VIII:C to construct a preliminary epitope map of these VIII:C polypeptides.
  • (17) Proteolysis and isolation of the labeled peptides using reverse phase HPLC and subsequent Edman sequence analysis detected and identified the thionitrobenzoate adducts of each of the three cysteinyl peptides of chloroperoxidase.
  • (18) Whole body protein turnover was accelerated by acidosis as reflected in a 70% increase in proteolysis and a 55% increase in protein synthesis.
  • (19) These results provide structural and functional evidence that CaM and CDP-I act synergistically in the regulated proteolysis of fodrin.
  • (20) The data do not support the suggestion that the toxin is derived by proteolysis of a protoxin precursor.

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