(superl.) Evil in great degree; dreadful; dismal; horrible; terrible; lamentable.
Example Sentences:
(1) Why is it so surprising to people that a boy like Chol, just out of conflict, has thought through the needs of his country in such a detailed way?” While Beah’s zeal is laudable, the situation in South Sudan is dire .
(2) It is that beautiful moment when the original Metamorphosis is destroyed so that it can be refashioned for a global community of readers in dire need of new forms of storytelling.
(3) In this investigation, reanalysis of responses to case vignettes obtained from 436 psychologists, psychiatrists, and internists revealed that on the issue of confidentiality management, these health care providers discriminate among cases involving: Premeditated harm to others, socially irresponsible acts with possible dire consequences to self or others, and minor theft.
(4) The report’s concluding chapters raised dire warning that the operations of contemporary child protection agencies were replicating many of the destructive dynamics of the Stolen Generations era.
(5) Tim Cook, the CEO of Apple, warned Barack Obama in public remarks this month that history had shown “sacrificing our right to privacy can have dire consequences”.
(6) Algeria had not scored a World Cup goal since they drew 1-1 with Northern Ireland at Mexico 1986, a run that took in five matches, including that dire 0-0 draw with England in Cape Town four years ago.
(7) Professor Lord Stern of the London School of Economics, the author of the influential Stern Report into the economics of climate change for the Treasury in 2006, warned that if the pattern continued, the results would be dire.
(8) High among the range of issues was the media dominance of the Globo group (whose journalists were chased away from demonstrations by an irate mob), inefficient use of public funds, forced relocations linked to Olympic real estate developments, the treatment of indigenous groups, dire inequality and excessive use of force by police in favela communities.
(9) Burrows had resigned as governor of Bank of Ireland, leaving the lender in dire straits, with big losses and mounting debt threatening its very survival.
(10) Yet the inability to get on in life is a now a major and growing problem for middle-class children and this group is in dire need of attention, it is expected to report.
(11) Vince Cable, their shadow chancellor, said: "The Liberal Democrats welcome the government's recognition that radical action is now needed, reflecting the dire and deteriorating position of the UK economy.
(12) Its willingness to ignore diplomatic convention and use its Kuala Lumpur embassy to conduct an extraterritorial assassination will be seen as setting a dire precedent that cannot be allowed to stand.
(13) What is clear, however, is that the reported escalation in fighting exacerbates the already dire humanitarian and human rights situation and the suffering of the Yemeni people,” said Ban’s spokesman, Farhan Haq.
(14) In a scene of young soldiers at rest for a few minutes at the front, he takes us into their heads: one full of dire forebodings, another singing, one trying to identify a bird on a tree – soldiers dreaming of girls’ breasts, dogs, sausages and poetry.
(15) Despite its own dire predictions on the potential impact of climate change , the government's impact assessment for Flood Re does not take account of " changing flood risk due to deterioration of existing flood defences [or] climate change".
(16) The situation is so dire the National Audit Office has warned that by 2020 schools will be worse funded than at any time since the mid-90s.
(17) John Macgregor, an aid worker who has been accompanying teams delivering food and water to Battambang, described the area as a vast inland sea where conditions are dire and malnutrition is common.
(18) But they are also the stuff of nightmares, because if an electricity grid is overwhelmed by demand, the consequences can be dire, as India discovered recently , when more than 700 million people were left without power.
(19) Thousands of jobs that would have been created will be lost and the knock-on effect will be so dire.
(20) While big businesses have enjoyed access to new couriers, Royal Mail itself eventually reached such a dire state that the Hooper report urged the government to rewrite the law to clarify that competition was a mixed blessing.
Drastic
Definition:
(a.) Acting rapidly and violently; efficacious; powerful; -- opposed to bland; as, drastic purgatives.
(n.) A violent purgative. See Cathartic.
Example Sentences:
(1) During the first three weeks of adaptation drastic changes in the parameter were seen.
(2) The differentiation between the various modes of involvement is essential as some of them may be confused with recurrence and the clinician might resort to unnecessary drastic measures like enucleation.
(3) Survival rates depend on age: 5 years survival rate of patients up to 65 years was 8,1% (59 of 729) and fell drastically in patients of 65+ years (28 of 1109 = 2,5%).
(4) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(5) Optic chiasm transection drastically diminished this ability, callosal section had little effect and combined lesions of these two structures abolished stereoperception.
(6) The observed drastic interstrain differences in dopamine receptor sensitivity demonstrate the essential role of genotype in the effects of dopaminergic drugs.
(7) Treatment of Xenopus laevis membranes with the 2',3'-dialdehyde of GTP (dial GTP) drastically inhibits their adenylyl cyclase activity.
(8) Ivermectin treatment of all cattle on a badly infected farm failed to interrupt the transmission of P. bovicola, even though ovipositional blood spots were drastically reduced in numbers for an entire summer season following treatment.
(9) The number of DAB positive organelles per surface area decreased steadily with culture age, and significantly on day 2 (p less than 0.01) to become drastically low on day 5 and negligible on day 7.
(10) However, treatment of intact worms drastically affected the integrity of the membrane.
(11) Treatment with glucocorticosteroids has drastically improved the prognosis.
(12) Only a drastic osmotic shock in distillated water as a mean to disrupt mitochondrial membrane was found to strongly increase the actual rate of the rotenone-sensitive activity.
(13) Such a drastic measure in an impossibly short timeframe would deprive generations of refugees of any choices for their future,” said Charles Gaudry, MSF’s head of mission in Kenya.
(14) In the deforming osteo-arthrosis (150 observations) in the synovial sheath there were usually noted drastic sclerosis and atrophy of organ-specific structures, impairmement of the production of the synovial fluid, and dystrophic falling into fibers of the articular cartilage with intensive proliferation of the cartilage cells.
(15) This was primarily due to the drastic decrease with age in excretion of bis-digitoxoside.
(16) The velocity of darkness adaptation was drastically changed in patients with chronic alcoholism but it was also reversible.
(17) The combined effects lead to a drastic antimutagenic effect, the molecular mechanism of which is given by these changes in mutagen-metabolizing enzymes.
(18) Decreasing the water concentration in the reaction medium by adding methanol at 0 degrees C drastically reduces the rate of racemization without affecting the rate of transamination.
(19) The factor production during a certain period of the development of lines is drastically increased by radiation.
(20) Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest.