What's the difference between disaggregation and segregation?
Disaggregation
Definition:
(n.) The separation of an aggregate body into its component parts.
Example Sentences:
(1) A comparison is made between these results and those of other authors who observed microtubule disaggregation by cold with the electron microscope.
(2) Human melanocyte cultures were established using disaggregated epidermal cell suspensions derived from foreskins and plated onto culture dishes in medium containing 2% fetal bovine serum, growth factors, hormones, and melanocyte growth factor (MGF) extracted from bovine hypothalamus (Wilkins et al., J.Cell.
(3) Insulin-induced hypoglycemia provokes polyribosome disaggregation and accumulation of monomeric ribosomes in the brain of rats with hypoglycemic paresis and coma.
(4) MB added after ADP-induced aggregation caused an increase in the amount of cytoskeletal core despite marked disaggregation and a substantial decrease in core-associated GP IIIa.
(5) Host cells were isolated by enzymatic disaggregation of the tumor and fractionated by sedimentation velocity at unit gravity on a Ficoll gradient.
(6) A study of 425 patients demonstrated that a pyodestructive process, located anywhere, affects platelet functional properties, resulting in the first place, in disorders of spontaneous cell disaggregation.
(7) These results are compared with those from studies of cells disaggregated from similar embryos.
(8) Our discrepancy with findings from the National Survey of Family Growth is evidence of the cultural diversity in the US Hispanic population and indicates the importance of disaggregating by ethnicity or national origin when studying this population.
(9) Lipase positivity was assessed using the Gomori technic with the conditions for fixation slightly modified to be suitable for disaggregated cells.
(10) The disaggregation of polysomes is an indication that the initiation step in protein synthesis is disrupted and is further evidence that the mechanism involved in protein synthesis arrest in dormant Artemia involves translational control.
(11) Disaggregated cell suspensions made from transplanted solid tumors, either chemically-induced fibrosarcomas, or spontaneous mammary carcinomas, can contain very high numbers of Fc receptor-bearing cells which are of host origin.
(12) Maximum aggregation takes place 1-3 min after fibrin-monomer addition, and then the disaggregation phase follows.
(13) Assays of progenitors from separately disaggregated yolk sacs and embryos from day-8 conceptuses yielded colonies only from yolk sac suspensions, and again these contained either HbE- and HbA-positive erythroblasts or only HbA-positive erythroblasts.
(14) In subsequent experiments, viability observed at 3 hr could be greatly increased if the tumors were cooled to 4 degrees C immediately after excision, and were then rapidly disaggregated.
(15) The hypothesis of calcium-related cell damage is based on the fact that dense ischemia leads to an influx of calcium into cells, and that raised intracellular calcium concentrations activate lipases and proteases, and cause disaggregation of neurotubuli and enhanced protein phosphorylation.
(16) This increases the thickness of the shield, thus inactivating or disaggregating the platelets.
(17) Treatment of isolated stratum corneum with certain detergents results in complete disaggregation of the corneocytes within hours at 45 degrees C without agitation.
(18) Osteoclasts disaggregated from neonatal rat long bones were settled onto devitalized cortical bone substrate, and resorption was quantified by morphometry.
(19) The results revealed that aflatoxin B1 rapidly led to disaggregation of free and membrane-bound polyribosomes, to inhibition of in vitro protein synthesis by both populations of polyribosomes, to little or no effect on the activities of initiation factors, and to defective ribosomes, particularly the 60S ribosomal subnits, of both types of polyribosomes.
(20) When developing cultures of Dictyostelium discoideum are disaggregated at any time prior to cell wall formation and challenged to reinitiate development, amoebae will progress through the original sequence of morphogenetic stages, but the second time through they will do so in roughly one-tenth the original time, a process known as 'rapid recapitulation'.
Segregation
Definition:
(n.) The act of segregating, or the state of being segregated; separation from others; a parting.
(n.) Separation from a mass, and gathering about centers or into cavities at hand through cohesive attraction or the crystallizing process.
Example Sentences:
(1) However, the average age at onset of lymphoma varied considerably among the different AKXD strains, suggesting that they have segregated several loci that affect lymphoma susceptibility.
(2) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(3) Reciprocal translocations involving the short arm of acrocentric chromosomes can segregate to produce partial duplications without associated deletions.
(4) Cellular responses in vitro to H-2D region histocompatibility antigens were demonstrated to be under the genetic control of two or three (P = 0.013) independently segregating loci.
(5) Recombination between markers was observed in matings between phage beta and the heteroimmune corynebacteriophages gamma and L. In such matings between heteroimmune phages the c markers of phages beta and gamma failed to segregate from the imm markers which determine the specificity of lysogenic immunity in these phages.
(6) For analytical purposes, irradiated dogs were segregated into groups according to their clinical status: clinically normal, hypocellular, or with acute non-lymphocytic leukemia.
(7) Interestingly, actinomycin D treatment dissociated centromeres from localization within the segregated nucleolus.
(8) In contrast, hybrids segregating human chromosomes contain both human and murine histone mRNAs, yet synthesize only mouse histone proteins.
(9) Models incorporating linear spatial-frequency- and orientation-selective channels explain many aspects of visual texture segregation.
(10) On the basis of segregating phenotypes, the genetic potentials of these compatible nocardiae were ascertained as follows: the formation of a diploid with subsequent segregation of parental or haploid recombinant genomes or both; persistence of the diploid through many generations; continuing reassortment of genetic information by multiple matings between parental or recombinant organisms; and, very probably, second-round recombinations within the diploid.
(11) The £77m, split between Manchester, Leeds, Birmingham, Newcastle, Bristol, Cambridge, Oxford and Norwich, will help improve existing cycle networks and pay for new ones, creating segregated routes in some areas.
(12) In addition, predominant peripheral or axial disease appeared to segregate with different B27 haplotypes.
(13) Oligomenorrhea was frequently found but segregated separately from the thyroxine-binding globulin deficiency; of seven women with low levels, three had normal monthly menstrual cycles.
(14) The Multidimensional Personality Questionnaire (MPQ) was administered to members of nuclear families in which alcoholism was segregating and another set of nuclear families in which no psychiatric illness, including alcoholism, was present.
(15) Here we report evidence of at least four independently segregating loci in the mouse homologous to the M31 cDNA.
(16) Some of these transductants segregated certain F14 genes, indicating they were carried on self-replicating genetic elements, but others were not cured of F14 markers, even by acridine orange.
(17) These conclusions were derived from infectious center studies on segregated cell populations, as well as from ultrastructural analyses on cells labeled with specific markers.
(18) This 'segregate RF', however, is not homogenous: i.e.
(19) The combined results describe the depth of segregation of DMS blocks in Avcothane, the presence of DMS within the topmost 20 A in Biomer, and similar impurities in the model polymers.
(20) Recently, cDNA clones encoding several bovine CKI isoforms have been sequenced that show high sequence identity to the HRR25 gene product of the budding yeast Saccharomyces cerevisiae; HRR25 is required for normal cellular growth, nuclear segregation, DNA repair, and meiosis.