(1) However, no evidence could be discerned to support its validity as a measure of a patient's treatment outcome.
(2) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(3) This was apparent by standard flux techniques only in low (65 mM) Na solutions, but was readily discernible in normal Na (125 mM) with the "lanthanum-residual" technique.
(4) By this method two types of granules have been discerned according to their different contrasts.
(5) Several stages in its histogenesis may be discerned: I. focal necroses of hepatic cells associated with their invasion with lister Listeria; 2. appearance of cellular elements around the foci of necroses with subsequent formation of granulemas consisting mainly of leucocytes and lymphoid cells; 3. development of necrobiotic changes in the central areas of granulemas with concomitance of exudative processes; 4. organization of necrotic foci with subsequent scarring.
(6) Significant increment in lipid peroxidation was discernible in brain, liver and muscle.
(7) While there's no discernible forró influence in the dreamy 80s indie-guitar music of Fortaleza's Cidadão Instigado, they do take influence from popular local style brega, a 1970s and 80s Brazilian romantic pop music.
(8) Furthermore, individual AgNOR dots were much more readily discerned in cell imprints than in sections, and this appears to be the method of choice if pathologists wish to at least approach absolute rather than relative AgNOR counts.
(9) In order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken.
(10) Changes in the secretory process were discernible as of day 1 in all three tumors, with a dramatic reduction of exocytosis and intracellular accumulation of PRL-immunoreactive granules.
(11) The advent of cyclosporine A provides the dermatologist with a new therapeutic strategem in the management of psoriasis, although the long-term safety of such interventional therapy remains to be discerned.
(12) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(13) However, by phase microscopy, no changes are discernible within the first 12-18 h. Since the primary NGF receptor appears to be a membrane receptor, it seemed likely that some of the initial responses to the factor may be surface related.
(14) Whereas no discernible differences on survival were documented on a long-term basis, when patient who ultimately recurred in each group were compared, a substantial and statistically significant prolongation of the free-of-disease interval from surgery to recurrence and of survival from recurrence to death are revealed.
(15) The results suggest that TGF-beta 1 has powerful anti-inflammatory effects, mimicking in some respects the beneficial effects of immunosuppressive drugs in these experimental models of autoimmune disease, but without discernable adverse effects.
(16) Temporal differences in the expression of sugar-binding proteins and different patterns of staining of the component cell types of human placenta were discerned, especially pronounced for alpha-fucoside-specific binding in the trophoblast and alpha-glucoside-specific binding in fetal and maternal macrophages.
(17) They’re all basically the same, but the tiny, barely discernible differences between them consume vast amounts of energy and generate heartache for everyone involved.
(18) Judged radiographically, partial obliteration (pulp chamber not discernible, root canal markedly narrowed but clearly visible) had occurred in 44 teeth (36%).
(19) Starch ingestion had no discernible effect on postprandial lipemia.
(20) We conclude that long-term prophylaxis with TMP-SMZ does not produce discernable hematologic, renal, or hepatic toxicity in renal transplant recipients nor does it augment nephrotoxicity with cyclosporine or increase the risk of rejection.
Insight
Definition:
(n.) A sight or view of the interior of anything; a deep inspection or view; introspection; -- frequently used with into.
(n.) Power of acute observation and deduction; penetration; discernment; perception.
Example Sentences:
(1) I want to get some good insight before I make my decision,” said Hiddink.
(2) The metabolism of [1,3-14C]benzo[f]quinoline (BfQ) by liver microsomes from control, 3-methylcholanthrene (3-MC)-pretreated and phenobarbital (PB)-pretreated rats has been investigated in order to gain insights into the effect of mixed function oxidase inducers on the types and levels of specific metabolites as formed in vitro.
(3) Further exploration of these excretory pathways will provide interesting new insights on the numerous cholestatic and hyperbilirubinemic syndromes that occur in nature.
(4) This quantitative characterization of the properties of conduction and refractoriness of both the accessory pathway and ventriculoatrial conduction system and the relation between these characteristics and the accessory pathway location in ART patients provides additional insight into the prerequisites for the initiation and maintenance of this rhythm disturbance.
(5) Tests were chosen to assess various aspects of monocyte function that give some insight into the host defense status and the degree of "activation" of the monocyte.
(6) A variety of homobifunctional crosslinking agents have been used to gain insight into the nature of the murine interleukin 3 (mIL-3) receptor.
(7) Although not common, the disorder is the most frequently diagnosed disturbance of porphyrin metabolism in many countries, and further insight into its unusual pathogenesis may clarify the hepatotoxic effects of the 4 etiologic agents.
(8) He captivated me, but not just because of his intellect; it was for his wisdom, his psychological insights and his sense of humour that I will always remember our dinners together.
(9) Families were randomly assigned to one of two forms of conjoint therapy: an Insight-oriented treatment (N = 10) or a Problem-Solving intervention (N = 10).
(10) We document for the first time abnormal microenvironments in thymomas that may offer insights into understanding normal thymic differentiation.
(11) Mark Latham's insights, insults and feuds are why he's worth reading | Gay Alcorn Read more BuzzFeed political editor Mark Di Stefano, the reporter who broke the story linking Latham to the less-than-savoury @RealMarkLatham Twitter account , had been chasing Stutchbury for days.
(12) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(13) A more current view of science, the Probabilistic paradigm, encourages more complex models, which can be articulated as the more flexible maxims used with insight by the wise clinician.
(14) By sharing insights and best practice expertise through [the Electrical and Electronic Equipment Sustainability Action Plan] esap and other platforms, Wrap believes business models such as trade-in services will be a reality in the next three to five years.” The actions of the 51 signatories to esap include: implementing new business models such as take-back and resale; extending product durability; and gaining greater value from reuse and recycling.
(15) To gain further insight into the side chain requirement at position 177 that confers maltose recognition, further substitutions of isoleucine, leucine, phenylalanine, proline, and serine have been made via site-directed mutagenesis.
(16) New insights into the biochemical and cell-biological alterations occurring in articular cartilage during the early phase of osteoarthrosis (OA) have been gained in the past decade by analysing experimentally induced osteoarthrosis in animals, mostly dogs and rabbits, while early phases of OA in humans so far have escaped diagnostic evaluation.
(17) V-HeFT, the first mortality trial in patients with heart failure, has provided important insights regarding trial design, including patient selection and efficacy criteria.
(18) The Guardian’s Jason Burke ( @burke_jason ) has insights into AQAP and al-Qaida in his frequent reportage for the Guardian.
(19) These new observations provide insight into the complex nature of GABAergic neurons and beta-cell GABA in regulation of islet function.
(20) This article will provide the nurse administrator with an insight into the development and implementation of a clinical career advancement program.