(1) We observed various macular pathologies in the form of macular stippling, retinal pigment epithelial defects, colloids & disciform lesions all in NIDDM patients, 70% of whom were uncontrolled on therapy.
(2) The hemorrhage arose from the extrachoroidal neovascular vessels within the disciform lesions and caused rupture of the retinal pigment epithelium with massive intraocular hemorrhage.
(3) Scanning electron microscopy of the endothelium of experimental disciform keratitis revealed corneal endothelial changes which distinguished disciform oedema from the more progressive stages of disciform keratitis.
(4) A retrospective evaluation of 61 consecutive age-related disciform macular degeneration patients who received green argon-laser photocoagulation was done to evaluate the visual results and to search for characteristics of the presenting lesion that correlated with prognosis.
(5) Kappa for each of these characteristics ranged from 0.46 to 0.71 in eyes of patients with bilateral nonexudative AMD and from 0.59 to 0.80 in the fellow eye of patients with unilateral exudative AMD (disciform scarring or macular changes associated with choroidal neovascularization).
(6) We treated five patients, aged 26, 4, 6, 13, and 7 years, who developed disciform stromal keratitis one, four, four, eight, and ten weeks, respectively, after the onset of the acute vesicular exanthema.
(7) The drusen characteristics of 38 eyes from 38 patients with bilateral drusen associated with age-related macular degeneration (AMD) were compared in a masked fashion to 89 fellow eyes from 89 patients with unilateral exudative AMD (disciform scarring or choroidal neovascularization).
(8) The patients included dendritic keratitis 7 cases, geographic keratitis 7 cases, disciform keratitis 7 cases, metaherpetic keratitis 5 cases, necrotic stromal keratitis 5 cases, and inactive herpetic keratitis 11 cases; 21 healthy subjects served as controls.
(9) The purpose of this study is to identify clinical, ultrasonographic, and fluorescein angiographic features of extramacular disciform lesions that allow differentiation from uveal tumors.
(10) From the morphologic point of view, we propose that the process leading to disciform scar formation in SMD begins with thickening of the inner aspect of Bruch's membrane due to production of abnormal basement membrane by the RPE.
(11) This was a retrospective study of 19 patients referred to our ocular oncology unit with a possible malignancy who had a diagnosis of an extramacular disciform lesion made after complete evaluation.
(12) Four of the eleven patients also presented disciform macular detachment and choroidal neovascularisation.
(14) Three clinical pictures could be differentiated biomicroscopically: focal iritis, peripheral endotheliitis, and prolonged disciform keratitis.
(15) It is proposed that vitreous fluorophotometry could be used to identify those patients developing disciform degeneration at an early and therefore potentially treatable stage.
(16) We postulate that drusen are precursors of disciform macular degeneration in fellow eyes and are probably manifestations of the same exudative process.
(17) The pigment epithelial disease was unresponsive to systemic corticosteroid therapy and tended to be complicated by disciform lesions.
(18) A combination of the above, noninvasive techniques can be used to correctly diagnose extramacular disciform lesions.
(19) Since the ocular anatomy is similar in monkeys and in man, there remains the necessity to reproduce the hemorrhagic disciform lesion of the macula, which represents the gravest aspect of presumed ocular histoplasmosis.
(20) Pathologic characteristics typical of age-related macular degeneration occurred in nine of the 90- to 101-year-old group with changes ranging from early neovascularization to fully developed disciform scars, geographic atrophy, and macular holes.
Flat
Definition:
(superl.) Having an even and horizontal surface, or nearly so, without prominences or depressions; level without inclination; plane.
(superl.) Lying at full length, or spread out, upon the ground; level with the ground or earth; prostrate; as, to lie flat on the ground; hence, fallen; laid low; ruined; destroyed.
(superl.) Wanting relief; destitute of variety; without points of prominence and striking interest.
(superl.) Tasteless; stale; vapid; insipid; dead; as, fruit or drink flat to the taste.
(superl.) Unanimated; dull; uninteresting; without point or spirit; monotonous; as, a flat speech or composition.
(superl.) Lacking liveliness of commercial exchange and dealings; depressed; dull; as, the market is flat.
(superl.) Below the true pitch; hence, as applied to intervals, minor, or lower by a half step; as, a flat seventh; A flat.
(superl.) Not sharp or shrill; not acute; as, a flat sound.
(superl.) Sonant; vocal; -- applied to any one of the sonant or vocal consonants, as distinguished from a nonsonant (or sharp) consonant.
(adv.) In a flat manner; directly; flatly.
(adv.) Without allowance for accrued interest.
(n.) A level surface, without elevation, relief, or prominences; an extended plain; specifically, in the United States, a level tract along the along the banks of a river; as, the Mohawk Flats.
(n.) A level tract lying at little depth below the surface of water, or alternately covered and left bare by the tide; a shoal; a shallow; a strand.
(n.) Something broad and flat in form
(n.) A flat-bottomed boat, without keel, and of small draught.
(n.) A straw hat, broad-brimmed and low-crowned.
(n.) A car without a roof, the body of which is a platform without sides; a platform car.
(n.) A platform on wheel, upon which emblematic designs, etc., are carried in processions.
(n.) The flat part, or side, of anything; as, the broad side of a blade, as distinguished from its edge.
(n.) A floor, loft, or story in a building; especially, a floor of a house, which forms a complete residence in itself.
(n.) A horizontal vein or ore deposit auxiliary to a main vein; also, any horizontal portion of a vein not elsewhere horizontal.
(n.) A dull fellow; a simpleton; a numskull.
(n.) A character [/] before a note, indicating a tone which is a half step or semitone lower.
(n.) A homaloid space or extension.
(v. t.) To make flat; to flatten; to level.
(v. t.) To render dull, insipid, or spiritless; to depress.
(v. t.) To depress in tone, as a musical note; especially, to lower in pitch by half a tone.
(v. i.) To become flat, or flattened; to sink or fall to an even surface.
(v. i.) To fall form the pitch.
Example Sentences:
(1) Michael James, 52, from Tower Hamlets Three days after telling his landlord that the flat upstairs was a deathtrap, Michael James was handed an eviction notice.
(2) A tiny studio flat that has become a symbol of London's soaring property prices is to be investigated by planning, environmental health and fire safety authorities after the Guardian revealed details of its shoebox-like proportions.
(3) With the flat-fee system, drug charges are not recorded when the drug is dispensed by the pharmacy; data for charging doses are obtained directly from the MAR forms generated by the nursing staff.
(4) Taking into account the calculated volume and considering the triangular image as one face of the particle, it is suggested that eIF-3 has the shape of a flat triangular prism with a height of about 7 nm and the above-mentioned side-lengths.
(5) He gets Lyme disease , he dates indie girls and strippers; he lives in disused warehouses and crappy flats with weirded-out flatmates who want to set him on fire and buy the petrol to do so.
(6) The b-wave in the ERG was lacking and the EOG was flat.
(7) In north-west Copenhagen, among the quiet, graffiti-tagged streets of red-brick blocks and low-rise social housing bordering the multi-ethnic Nørrebro district, police continued to cordon off roads and search a flat near the spot where officers killed a man believed to be behind Denmark’s bloodiest attacks in over a decade.
(8) Distance running performance is slower on hilly race courses than flat courses even when the start and finish are at the same elevation, resulting in equal amounts of uphill and downhill running.
(9) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
(10) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(11) All other broad-spectrum benzimidazole anthelmintics, regardless of substituent at the 2 position (methyl carbamate or thiazolyl group), are flat.
(12) We investigated the mechanism by which retinoic acid causes growth arrest and flat reversion of SSV-NRK, simian sarcoma virus-transformed normal rat kidney cells.
(13) When she speaks, it is in a quiet, clear voice that is middle-class but also flat and London-inflected enough to seem almost classless: it is the voice of the modern southern English professional.
(14) After about 3 weeks of culture, N-ethyl-N-nitrosourea-pretreated fetal rat brain cells showed focal proliferation of neural cells on an underlayer of flat, epithelioid cells.
(15) In order to determine an histological high-risk group, we chose cases with preneoplastic conditions (60 CAG, 10 biopsies of gastric remnants, 3 flat adenomas and 55 gastrectomies by cancer or ulcer).
(16) During inspiration, the velocity was greater and the shape of the flow profile throughout diastole tended to be flat.
(17) The following relationships were found: Round nuclei have higher rates of DNA synthesis than flat ones.
(18) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(19) Microinfusion of the selective 5-HT1A receptor agonist, 8-hydroxy-(di-N-propylamino)tetralin (8-OHDPAT), into the dorsal raphe nucleus (DRN) produced a marked behavioural hypoactivity and flat body posture.
(20) Don was racing the Dodge through the Bonneville Salt Flats , where Gary Gabelich had just (on 23 October) broken the land-speed record.