(v. t.) To destroy or disturb the comfort of; to deprive o/ quiet enjoyment; to make uneasy; to pain; as, a smoky chimney discomforts a family.
(v. t.) Discouragement.
(v. t.) Want of comfort; uneasiness, mental or physical; disturbance of peace; inquietude; pain; distress; sorrow.
Example Sentences:
(1) In this group there was only one case of mild ankle discomfort (3.5%).
(2) In some experiments heart rate and minute ventilation (central vactors) appear to be the dominant cues for rated perceived exertion, while in others, local factors such as blood lactate concentration and muscular discomfort seem to be the prominent cues.
(3) Clinical measurements of the loudness discomfort level (LDL) are generally performed while the subject listens to a particular stimulus presented from an audiometer through headphones (AUD-HP).
(4) A patient with abdominal discomfort and hematemesis was found to have lower esophageal inflammation on endoscopy.
(5) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
(6) Panic disorder subjects showed a negative relationship between pulmonary function and hyperventilation symptoms, suggesting a heightened sensitivity to, and discomfort with, sensations associated with normal pulmonary function.
(7) Polls indicated that anger over the government shutdown, which was sharply felt in parts of northern Virginia, as well as discomfort with Cuccinelli's deeply conservative views, handed the race to McAuliffe, a controversial Democratic fundraiser and close ally of Bill and Hillary Clinton.
(8) The degree of discomfort was slightly greater in women who complained of breast tenderness within three days prior to the mammogram but was not strongly related to age, menstrual status, or week of the menstrual cycle.
(9) Independent t test results indicated nurses assigned more importance to psychosocial support and skills training than did patients; patients assigned more importance to sensation--discomfort than did nurses.
(10) A 27-year-old lady presented with history of discomfort in the throat and difficulty in swallowing for two weeks.
(11) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(12) Doubtless the regulators will make their discomfort clear to government," he added.
(13) The rationale for this assumption seems logical because using all of the available accommodation is not sustainable without discomfort.
(14) He came to our hospital with the chief complaint of discomfort of the anterior chest.
(15) Naproxen sodium compared favourably with the placebo with respect to pelvic pain and overall discomfort.
(16) The patient was referred to the podiatry department because of continued discomfort and the inability to run.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Less than 50% gained complete relief, however, and 58% experienced persistent discomfort in certain types of shoes.
(19) Defatting with acetone as part of the regimen for cutaneous disinfection does not improve microbial removal or reduce the incidence of catheter-related infection, but increases cutaneous inflammation and patient discomfort.
(20) The decrease in saliva causes chronic oral discomfort and functional problems and predisposes patients to dental caries and oral candidiasis.
Prickle
Definition:
(n.) A little prick; a small, sharp point; a fine, sharp process or projection, as from the skin of an animal, the bark of a plant, etc.; a spine.
(n.) A kind of willow basket; -- a term still used in some branches of trade.
(n.) A sieve of filberts, -- about fifty pounds.
(v. t.) To prick slightly, as with prickles, or fine, sharp points.
Example Sentences:
(1) Some peculiarities in the ultrastructure of these neurones were described as the presence of prickles, fringes.
(2) Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle.
(3) Prickle cell masses invaded into the soft tissue in the deeper layer.
(4) In some of the distal and middle dendrites and dendritic spines [correction of prickles] in elderly ground squirrels there were plaques, composed of electron-dense material with structure similar to postsynaptic condensations, but without presynaptic specializations of chemical synapses.
(5) Desmosomes are most frequent in the prickle cell layer, where desmosome fields may occur, and in the lower functional cell layer.
(6) Membrane coating granules first reaching a maximum in the functional cell layer appeared in the upper prickle cell layer and few persisted into the surface cells.
(7) Oral discomfort such as prickling and burning sensations, metallic and bad taste was rare in both diabetics and non-diabetics.
(8) Gap junctions (nexuses) were observed primarily in the basal and prickle cell layers.
(9) Beginning to feel the first prickles of boredom, I thought of young Nathan, for whom Minecraft was life, until it wasn't.
(10) The emigrating ERM from PDL explants, as well as occasional proliferating ERM within explants, consisted of two cell types--outer basal-like cells, as described above, and inner tonofilament-rich prickle-like cells, suggesting a propensity for differentiation of ERM.
(11) Three layers were identified, as in the light microscopy of the oesophageal epithelium: basal, prickle and funtional cell layers.
(12) This system was attached to the upper arms of young adult volunteers who increased the voltage of the rectangular electrical pulses supplied to the electrodes until a reproducible sharp prickling pain sensation was perceived.
(13) Various cells were observed in expanded intercellular spaces of basal cell and prickle cell layers.
(14) CRBP concentrations were highest in maturing keratinocytes within the prickle cell layers of normal mucosa and in laryngeal papillomas, as estimated on the basis of immunoreactivity to CRBP.
(15) The fluid phase marker was taken up most avidly by the prickle cells but to a lesser extent in the functional layers and by basal cells.
(16) Light microscopical findings: Leukoplakia exhibited orthokeratinization and the thickening of prickle and corneal cell layers was seen.
(17) Prickling of the skin and hirsutism were common side-effects.
(18) In all sections of leukoplakia, the positive cells for EGFr were found in the prickle cell layer in addition to the basal cell layer.
(19) Each subject judged only one single pair with respect to which one tasted more fizzy ("spritziger"), dry ("trockener"), prickling ("prickelnder") and better ("besser").
(20) Untoward effects experienced in volunteers receiving BW 942C included heaviness in the limbs, nasal stuffiness, mouth dryness, facial flushing, skin rash, and prickling sensations.