(a.) Disjunctive; containing a disjunctive or discretive clause; as, "I resign my life, but not my honor," is a discrete proposition.
(a.) Separate; not coalescent; -- said of things usually coalescent.
(v. t.) To separate.
Example Sentences:
(1) Therefore, neither of these two regions of the Tat protein appear to be discrete activation domains.
(2) Interphase death thus involves a discrete, abrupt transition from the normal state and is not merely the consequence of progressive and degenerative changes.
(3) One of the HEF bands can be separated from two others with beta-alanine as discrete spacer.
(4) In the heart, myocarditis is often discrete, and may be complicated by perivascular fibrosis and rare foci of myocytolysis; in some cases primary lymphomas may also develop.
(5) The p30 proteins of murine viruses also contain a second discrete set of antigenic determinants related to those in infectious primate viruses and endogenous porcine viruses, but not detected in the feline leukemia virus group.
(6) These transformants were found to possess discrete Hind III fragments containing human Alu family sequences which were conserved in several independent secondary transformants.
(7) These results demonstrate, in living human hearts, that diffuse coronary atherosclerosis is often present when coronary angiography reveals only discrete stenoses.
(8) The appearance of an abundant class of polyribosomes was correlated with globin synthesis by demonstrating that a discrete class of polyribosomes arises in cells treated with the inducers hexamethylene bisacetamide and hemin.
(9) We conclude that: 1) the effective capillary PO2 in the fetal brain can be significantly reduced by increasing the distance between non-methemoglobin-laden erythrocytes in capillaries and 2) hypoxic inhibition of fetal breathing probably arises from discrete areas of the brain having a PO2 less than 3 Torr.
(10) The ligands bind at discrete sites in the minor groove of DNA, and analysis on DNA sequencing gels show pronounced protection at the ligand binding sites, as well as more generalized protection.
(11) Stuart Forman and Keith Miller describe the physiological, biophysical and molecular biological evidence pointing to the location of a discrete allosteric site on the nicotinic acetylcholine receptor at which local anesthetics act.
(12) The lesion presented as a discrete, palpable mass that led to orchiectomy.
(13) There were discrete linear relationships between muscle temperature and isometric endurance associated with cycling at 60% and 80% VO2max.
(14) Six discrete 'phased' nucleosomes are present upstream from the gene and are modulated by induction.
(15) The anterior division can be further parcellated into dorsal, lateral, and ventral areas, and each of these areas, along with the posterior division, can be thought of as containing more-or-less discrete nuclei embedded within a relatively undifferentiated region.
(16) Thus, SA may be controlled by a discrete number of motoneuron task groups reflecting a small number of central command signals or by a continuum of activation patterns associated with a continuum of moment arms.
(17) A CT scan of the brain showed numerous small discrete lesions.
(18) The starting dose of paroxetine was 20 mg daily and of amitriptyline 75 mg daily in divided doses; at week 3 these doses could be increased at the investigators' discretion.
(19) By using regression analysis on a series of subsets of Ra3 responders and nonresponders, we obtained data supporting the concept of discrete "responder" and "nonresponder" phenotypes.
(20) These observations suggest that the inner dynein arms in Chlamydomonas axonemes are aligned not in a single straight row, but in a staggered row or two discrete rows.
Topology
Definition:
(n.) The art of, or method for, assisting the memory by associating the thing or subject to be remembered with some place.
Example Sentences:
(1) The scheme is based on topological information, i.e.
(2) These results provide knowledge of the interrelationships between antibiotic and substrate ribosome binding sites which should eventually contribute to a map of ribosomal topology.
(3) The conformational properties of these new TASPs are now under investigation, with special emphasis on the relationship between overall conformation and the nature of the topological template.
(4) In the context of a simplified diamond lattice model of a six-member, Greek key beta-barrel protein that is closely related in topology to plastocyanin, the nature of the folding and unfolding pathways have been investigated using dynamic Monte Carlo techniques.
(5) At the Second Scandinavian Congress on Image Analysis in 1981 Kohonen provided evidence that the map of signals has the same topological order as the map of reactions.
(6) Phylogenetic analysis of the aligned sequences by both phenetic and cladistic methods with H. perryi as an outgroup generated one best topology which pairs S. alpinus with S. malma as the most recently derived species, and pairs S. confluentus with S. leucomaenis.
(7) Then, a 'hyperstructure matrix' is generated, containing the unique topological relationship between every pair of regions.
(8) Linear DNA substrates in which pairing is topologically restricted to a paranemic joint also follow this relationship.
(9) The subgroups of carcinoma of the bladder, determined by topology, have markedly different long-term prognoses.
(10) The fluorescence properties of Hoechst 33342 (HO 33342) were examined with plasmid pBR322 in the supercoiled (Form I) or relaxed covalently closed circular (Form Io) conformation in order to determine whether qualitative or quantitative differences in fluorescence properties might provide an assay for topological states of DNA.
(11) An exhaustive search of all possible trees also supported this topology, although one haplotype had to be eliminated from this analysis to save computer time.
(12) This superfamily of proteins is predicted to share the topology of the seven transmembrane helices of bacteriorhodopsin (BR), even though no significant sequence homology had been identified.
(13) These data demonstrate the utility of this approach for determining membrane protein topology and extend potential applications to include at least some proteins not normally expressed in E. coli.
(14) The unique topology of the products indicates that resolvase fixes the sum of the number of supercoils between recombination sites at synapsis and the number of such supercoils lost or gained during strand exchange.
(15) Such explanations are possible because the relatively few structural proteins of the erythrocyte are regularly distributed over the entire cytoplasmic surface of the cell membrane and because the well-understood topological associations of these proteins seem to be stable in comparison with the time required for the cell to change shape.
(16) The objectives of the present investigations were to document a composite, new approach for the evaluation of the structure-function dependencies of proteins based on the analysis of the informational content of the primary amino acid sequence as well as the topological and functional regions of a protein.
(17) When the input topology is supercoiled, high levels of transcription are observed, whereas input relaxed DNA is transcribed to a much lower extent.
(18) It is believed that one or more basic residues at the extreme amino terminus of precursor proteins and the lack of a net positive charge immediately following the signal peptide act as topological determinants that promote the insertion of the signal peptide hydrophobic core into the cytoplasmic membrane of Escherichia coli cells with the correct orientation required to initiate the protein export process.
(19) We observe that the effect of osmotic shock is an elevation of superhelical tension; quantitative comparison with changes in plasmid linking number indicates that the alteration in DNA topology is all unconstrained.
(20) Anomalous correspondence most probably has its seat where the retinal topology is not exact, i.e., where the binocular receptive fields are very large and encompass the corpus callosum, such as in area 20 or 21.