(n.) Lack of ease; uneasiness; trouble; vexation; disquiet.
(n.) An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
(v. t.) To deprive of ease; to disquiet; to trouble; to distress.
(v. t.) To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
Example Sentences:
(1) Forty-nine patients (with 83 eyes showing signs of the disease) were followed up for between six months and 12 years.
(2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(3) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(6) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(7) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(8) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(9) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(10) Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.
(11) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(12) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
(13) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(14) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(15) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(16) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(17) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(18) Road traffic accidents (RTAs) comprised 40% and ischaemic heart disease (IHD) 13% of the total.
(19) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
(20) Measurement of urinary GGT levels represents a means by which proximal tubular disease in equidae could be diagnosed in its developmental stages.
Glanders
Definition:
(n.) A highly contagious and very destructive disease of horses, asses, mules, etc., characterized by a constant discharge of sticky matter from the nose, and an enlargement and induration of the glands beneath and within the lower jaw. It may transmitted to dogs, goats, sheep, and to human beings.
Example Sentences:
(1) The experiments showed basic possibilities to perform rapid estimation (for at least 2 days) of drug efficacy in experimental glanders and melioidosis in golden hamsters.
(2) Membrane preparations were derived from the spheroplasts of glanders and melioidosis causative agents.
(3) The results of the in vitro studies showed that most of the antibiotics were not active against the glanders causative agent, except for polymyxin M, levomycetin and their combination.
(4) Among the four studied strains, the causative agent of glanders was the least resistant to the chemotherapeutic drugs.
(5) Discussed are coal miners' nystagmus, scrotal cancer in chimney sweeps, phossy jaw, hatters' shakes, painters' colic, potters' rot, chauffeurs' knee, glanders, caisson disease, and others.
(6) A dot enzyme-linked immunosorbent assay (dot ELISA) was developed for diagnosis of glanders in equines.
(7) Double immunodiffusion in gel test was used to determine the antigenic composition of the preparations of membranes isolated from the lysozyme spheroplasts of glanders (strain No.
(8) Of the antibiotics studied penicillin was more useful for obtaining melioidosis spheroplasts and ampicillin--for glanders spheroplasts.
(9) The rapid method developed by the authors was recommended for the use in primary estimation of the efficacy of new drugs in the treatment of tularemia, glanders and melioidosis.
(10) The authors examined the ultrastructure of the causative agents of glanders and melio idosis.
(11) Sensitivity of the glanders causative agent to 20 antibiotics representing different groups is described.
(12) A study of antimembrane sera in the agglutination and immunofluorescence tests demonstrated a heterogeneity of the glanders and melioidosis strains under study by the membrane thermolabile antigen.
(13) Spheroplasts were obtained from the causative agents of glanders and melioidosis under the effect of lysozyme and antibiotics.
(14) In the capacity of an inducing agent lysozyme was effective in high concentration only (0.4%); preliminary washing and incubation in sucrose were necessary to obtain glanders spheroplasts.