(n.) Lack of ease; uneasiness; trouble; vexation; disquiet.
(n.) An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
(v. t.) To deprive of ease; to disquiet; to trouble; to distress.
(v. t.) To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
Example Sentences:
(1) Forty-nine patients (with 83 eyes showing signs of the disease) were followed up for between six months and 12 years.
(2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(3) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(6) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(7) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(8) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(9) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(10) Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.
(11) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(12) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
(13) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(14) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(15) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(16) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(17) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(18) Road traffic accidents (RTAs) comprised 40% and ischaemic heart disease (IHD) 13% of the total.
(19) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
(20) Measurement of urinary GGT levels represents a means by which proximal tubular disease in equidae could be diagnosed in its developmental stages.
Madness
Definition:
(a.) The condition of being mad; insanity; lunacy.
(a.) Frenzy; ungovernable rage; extreme folly.
Example Sentences:
(1) Do [MPs] remember the madness of those advertisements that talked of the cool fresh mountain air of menthol cigarettes?
(2) Right from the beginning, I had been mad about movies.
(3) "This will be not only be a postcode lottery, but a States vs Europe lottery and that would be madness."
(4) It took years of prep work to make this sort of Übermensch thing socially acceptable, let alone hot – lots of “legalize it!” and “you are economic supermen!” appeals to the balled-and-entitled toddler-fists of the sociopathic libertechian madding crowd to really get mechanized mass-death neo-fascism taken mainstream .
(5) Or perhaps the "mad cow"-fuelled beef war in the late 1990s, when France maintained its ban on British beef for three long years after the rest of the EU had lifted it, prompting the Sun to publish a special edition in French portraying then president Jacques Chirac as a worm.
(6) • +33 2 98 50 10 12, hotel-les-sables-blancs.com , doubles from €105 room only Hôtel Ty Mad, Douarnenez Hôtel Ty Mad In the 1920s the little beach and fishing village of Douarnenez was a favourite haunt of the likes of Pablo Picasso and writer and artist Max Jacob.
(7) If you’re against the RFS, you’re going to make Iowans mad, you’re going to [have] some Iowans question you but the beauty of Iowa is you can take your case to the people,” said Kaufmann.
(8) In its more loose, common usage, it's a game in which the rivalry has come to acquire the mad, rancorous intensity of a Celtic-Rangers, a Real Madrid-Barcelona, an Arsenal-Tottenham, a River Plate-Boca Juniors.
(9) Yes, we can assign more or less responsibility – I blame Austria-Hungary and Germany for their mad determination to destroy Serbia knowing that a general war might result – but there is still plenty of room for disagreement.
(10) It’s good to hear a full-throated defence of social security as a basic principle of civilisation, and a reiteration of the madness of renewing Trident; pleasing too to behold how much Burnham and Cooper have had to belatedly frame their arguments in terms of fundamental principle.
(11) The blue skipping rope – that’s the key to this race.” My eight-year-old daughter looked at me like I was mad … but when it came time for the year 3 skipping race, she did as she was told – and duly chalked up a glorious personal best in third place.
(12) The policies of zero tolerance equip local and federal law-enforcement with increasingly autocratic powers of coercion and surveillance (the right to invade anybody's privacy, bend the rules of evidence, search barns, stop motorists, inspect bank records, tap phones) and spread the stain of moral pestilence to ever larger numbers of people assumed to be infected with reefer madness – anarchists and cheap Chinese labour at the turn of the 20th century, known homosexuals and suspected communists in the 1920s, hippies and anti-Vietnam war protesters in the 1960s, nowadays young black men sentenced to long-term imprisonment for possession of a few grams of short-term disembodiment.
(13) Maleic acid dimethylester (MAD) was investigated in acute and subacute dermal toxicity studies, for sensitization potential, and for in vivo and in vitro genotoxicity.
(14) Or maybe it's the other way round - the constant touring is a manifestation of their madness.
(15) And while one may think that the bishops of the Church of England don’t quite have the sex appeal of Russell Brand, we think that we should counter it.” While the bishops stress that their letter is not intended as “a shopping list of policies we would like to see”, they do advocate a number of specific steps, including a re-examination of the need for Trident, a retention of the commitment to funding overseas aid and a reassessment of areas where regulations fuel “the common perception of ‘health and safety gone mad’”.
(16) He still thinks Labour was mad to get him of all people to work inside the system.
(17) That has changed over the past few years as wallpaper has made a comeback and women have remembered that they like wearing madly patterned dresses – particularly leopard-print ones, or ones with huge flowers.
(18) Seeing the performance later in Edinburgh, I was impressed by Briers' ability to encompass the hero's rage and madness.
(19) It would be hard to allow working from home if I thought that they were all watching box sets of Mad Men.
(20) People thought she'd gone mad, but in retrospect it's clear that this was precisely what she needed in order to move forward.