(n.) Lack of ease; uneasiness; trouble; vexation; disquiet.
(n.) An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
(v. t.) To deprive of ease; to disquiet; to trouble; to distress.
(v. t.) To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
Example Sentences:
(1) Forty-nine patients (with 83 eyes showing signs of the disease) were followed up for between six months and 12 years.
(2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(3) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(6) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(7) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(8) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(9) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(10) Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.
(11) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(12) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
(13) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(14) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(15) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(16) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(17) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(18) Road traffic accidents (RTAs) comprised 40% and ischaemic heart disease (IHD) 13% of the total.
(19) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
(20) Measurement of urinary GGT levels represents a means by which proximal tubular disease in equidae could be diagnosed in its developmental stages.
Pandemic
Definition:
(a.) Affecting a whole people or a number of countries; everywhere epidemic.
(n.) A pandemic disease.
Example Sentences:
(1) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
(2) The human immunodeficiency virus (HIV) has resulted in a worldwide pandemic of infection.
(3) The cholera-pandemic raging in South and Middle America and endemic cholera in other countries call for measures of health protection of the local population, but particularly with respect to the young, old, pregnant and immunocompromised citizens of countries importing food from the areas where the disease has struck.
(4) The seventh pandemic of cholera is still continuing (92 countries have so far been affected), and other organisms related to V. cholerae O1 are being reported increasingly frequently as the cause of diarrhoeal outbreaks as well as endemic diarrhoea.Recent research has considerably increased our understanding of how cholera is transmitted, the mechanisms by which V. cholera O1 produces disease, and the functioning of the local intestinal immune response by which individuals can be protected from infection.
(5) It is argued that prior to the present AIDS pandemic the efficiency of the rev receptor was enhanced by an ancestral recombination event.
(6) This study provides arguments that (1) strains of biotypes cholerae and El Tor are different clones, (2) a cholera pandemic is not a single world-wide epidemic (due to a single clone) but rather a simultaneous occurrence of several epidemics (several clones involved), and (3) epidemic waves of biotype El Tor could be due to the emergence of new clones.
(7) Two hypotheses are advanced for the range of hemagglutinin (HA) subtypes of viruses that can cause pandemics (1) circle or cycle limited to H1, H2, and H3 subtypes, thereby implying that a virus of the H2 subtype will cause the next pandemic; and (2) spiral, by which any one of the 14 HA subtypes recorded to date may be involved.
(8) This sequence is conserved in representative viruses from each of the major pandemics.
(9) The effect of the AIDS pandemic on the sexual behavior of the general population has not been clearly established.
(10) Mathematical modeling of the AIDS pandemic has been limited by the difficulty of satisfactorily representing the marked behavioral heterogeneity that characterizes the various populations at risk.
(11) Introductory comments are made regarding the seriousness of AIDS as a global pandemic, its initial identification and description, and the various patterns of epidemic spread observed throughout the world.
(12) The impact of the AIDS-pandemic on the social and economic structures will grow to very large dimensions in some countries.
(13) HIV is now a worldwide pandemic, affecting some ten million adults and one million children--the overwhelming majority from sub-Saharan Africa.
(14) (iv) The different virus lineages are predominantly host specific, but there are periodic exchanges of influenza virus genes or whole viruses between species, giving rise to pandemics of disease in humans, lower animals, and birds.
(15) Understanding of the nature and pathogenic mechanisms of the oral microbiota may lead to control of this pandemic infection.
(16) Only a limited number of A-subtypes of influenza virus so far caused disease in human subjects, pigs and horses; this occurred in more or less defined areas which occasionally showed epidemic aggravations, becoming apparent as rapidly spreading epidemics or otherwise in even the form of pandemics.
(17) This gap between discovery and disclosure allowed the Sony rootkit to become a global pandemic that infected hundreds of thousands of US military and government networks.
(18) The major antigenic changes in influenza A virus that occur at 10-year intervals reduce the effectiveness of existing vaccines and pose a problem for the control of pandemics by vaccination.
(19) These findings underline the importance of pigs as potential reservoirs for future human pandemics by the continued isolation (in Asia) of H3N2 and Hsw1N1 influenza viruses.
(20) Because prostitutes are viewed as a major source of a variety of sexually transmitted diseases (STDs), many researchers have studied their role in spreading the AIDS pandemic.