(v. t.) To separate or undo, as links; to uncoil; to unfasten.
Example Sentences:
(1) A cluster of unlinked genes encoding gluconeogenic enzymes in the mouse is characterized by the failure of normal hormone-inducible expression in animals homozygous for one of several overlapping deletions mapping on chromosome 7 near the albino locus.
(2) Four of the mutants had no effect on chylous ascites, but two mutants linked with ragged, and one unlinked, showed a complex situation involving enhancement, inhibition, epistacy and other interactions.
(3) At least two unlinked mutations were associated with such phenotypes.
(4) Strains with derepressed levels of the isoleucine and valine biosynthetic enzymes owing to linked or unlinked genetic lesions were found to exhibit ilv messenger RNA levels from 1.5- to 4-fold higher than did their isogenic parents.
(5) Several overlapping chromosomal deletions spanning the albino locus in the mouse cause perinatal lethality when homozygous and a block in the transcriptional induction of various unlinked hepatocyte-specific genes.
(6) The phenotypic expression of resistance at the fpaA locus can be suppressed by mutation of the str locus from str-s to str-r, whereas that at an unlinked fpa locus cannot.
(7) This inference is supported by the observation that a significant interaction (i.e., epistasis) was detected between the QTL(s) in the conserved region and an unlinked RFLP marker locus in both species.
(8) b) Locus TSM1 appears to be weakly linked to the locus PAR1 and to the loci RIB1 and RIB3 but unlinked to the locus OLI1.
(9) The three electrophoretic variants of phosphoglucomutase in Saccharomyces cerevisiae breeding stocks are produced by two unlinked genes, pgm-1 and pgm-2; pgm-1 contains two known alleles, pgm-1a and pgm-1b, each of which specifies a minor phosphoglucomutase component, and pgm-2 specifies the major phosphoglucomutase component.
(10) The "preferred" model specifying interaction between two major unlinked autosomal loci was confirmed indirectly by further breeding tests.
(11) The enzyme is an aggregate consisting of two protein components, coded for by the unlinked genes cpaI and cpaII.
(12) The second site is on chromosome III, unlinked to the centromere and distal to the mating type locus.
(13) Since in this study all unlinked genes segregated independently, this is direct evidence that MCF viruses participate in the induction of erythroleukemia.
(14) The segregation data indicate that the AKR mouse contains two unlinked, autosomal, chromosomal loci, either of which suffices to induce detectable levels of infectious virus in Fv-1(n) progeny by 6 wk of age.
(15) Additionally, we examined the combined data for evidence that a third, as yet unlinked locus exists.
(16) It is known that glnR5, a regulatory mutation unlinked to glnS, causes overproduction of glutaminyl-tRNA synthetase.
(17) relA and spoT are designations for two unlinked Escherichia coli genes whose products function in the synthesis and degradation of guanosine 3',5'-bispyrophosphate during the stringent regulatory response to amino acid deprivation.
(18) Allosuppressor (sal) mutations enhance the efficiency of the yeast ochre suppressor SUQ5 and define five unlinked loci, SAL1-SAL5.
(20) These data demonstrate that two unlinked transforming regions of human cytomegalovirus can cooperate to produce an aggressive tumorigenic phenotype.