(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Infirmity
Definition:
(a.) The state of being infirm; feebleness; an imperfection or weakness; esp., an unsound, unhealthy, or debilitated state; a disease; a malady; as, infirmity of body or mind.
(a.) A personal frailty or failing; foible; eccentricity; a weakness or defect.
Example Sentences:
(1) The thrust of health care "solutions" in the press and in Congress focus on the infirm.
(2) Those allocated a diagnosis of dementia were most impaired and confused, and those living in specialist homes for the mentally infirm were more impaired than other residents.
(3) Photograph: Eamonn Mccabe I is for Italy He lived for many years in a mountain-top retreat in Ravello on the Amalfi coast until he became too infirm to cope with the hills.
(4) Anyone who is pregnant, breastfeeding or infirm should talk to a GP before taking the herb.
(5) The cell bodies of the AVCN did not seem altered infirming a rapid, direct or indirect, neurotoxic effect of the drug.
(6) This paper describes one of the first attempts at an economic evaluation of a community care initiative for elderly mentally infirm people and their carers.
(7) It appears to become more severe with advanced age and other infirmities, such as immobility.
(8) It was one of at least half a dozen such unionist experiments, with a variety of partners, which foundered on the rocks of the would-be partners' infirmity of purpose, fear, suspicion and disdain of this bizarre, arrogant, impetuous upstart.
(9) While the courts welcome Russian oligarchs whose disputes have nothing to do with this country, they close their doors to the cheated, the battered and the infirm from the native poor.
(10) Swing your gaze from the aged and infirm to your fit and healthy peers here and abroad embracing fascism and poor-bashing.
(11) Other factors included pre-existing locomotor disorder or mental infirmity, unmanageable incontinence of urine after catheterisation, and institutional disorientation.
(12) The increasing infirmity of the aged often associated with tiredness, dyspnea and dizziness even without treatment requires careful instruction of the patient about effects and side effects of the prescribed medication.
(13) 11.01am BST Lord Norman Tebbit , the Tory former cabinet minister, says he worries such a bill would bring great pressure on the old, infirm or disabled to consider ending their lives so as to not be a financial burden on others.
(14) If "pain" in the broad sense of the term lends itself to objective evaluation with difficulty, it is not the same with respect to infirmity.
(15) The results of one such arrangement where a geriatrician was involved in the weekly review of the elderly mentally infirm patients are described.
(16) The dual rating system eliminates the problem of declining knee scores associated with patient infirmity.
(17) Neurotic applicants for an infirmity-pension belong to the group of problem patients for attending general practitioners and specialists alike.
(18) Please do not let us remember only the sick and infirm.
(19) Yet every local authority in the land allows men like these as well as our sick, elderly and infirm to be left to the tender mercies of profiteers and cowboys.
(20) Now staff and volunteers hunched over the infirm, dispensing sips of water and fanning them with bits of cardboard.