(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Loneliness
Definition:
(n.) The condition of being lonely; solitude; seclusion.
(n.) The state of being unfrequented by human beings; as, the loneliness of a road.
(n.) Love of retirement; disposition to solitude.
(n.) A feeling of depression resulting from being alone.
Example Sentences:
(1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
(2) I used it primarily as a social lubricant but also to alleviate boredom, stress and loneliness.
(3) Symptom prevalence was associated with anxiety, negative relations with parents, modest plans for education, fear of the future, loneliness, smoking, and drinking.
(4) a person who experienced loneliness did usually not feel completely healthy.
(5) Other factors such as gender, marital status and the presence of children, relatives and friends in the neighbourhood had no association with loneliness.
(6) A median split on the UCLA Loneliness Scale divided subjects into high- and low-scoring loneliness groups.
(7) The epidemic of loneliness and isolation that is spreading through the older population is not confined to people waiting at home for the next visit from a homecare worker, but can be just as acute for the older person waiting in their care home room for the weekly visit from relatives, or even just from a staff member, as was distressingly illustrated by another Panorama exposé this week.
(8) The group differences and the varying patterns of correlations support the use of a multidimensional approach to the study of loneliness.
(9) The purpose of this study was to analyze differences in future time perspective, loneliness and perceived maternal expressiveness between adolescents who were chronically ill with cystic fibrosis and adolescents who were reportedly healthy.
(10) Loneliness and sociocultural isolation appeared to accelerate the rate at which the average "traveler" moved from nonaddictive use to addiction.
(11) Both groups completed two self-concept questionnaires, a loneliness scale, and a measure of their social relationships outside of school.
(12) Suggestions were made for future research on loneliness in school settings.
(13) Such schemes can help people of any age to develop self-acceptance, making it easier for them to relate to others and connect on such a level that loneliness, if not eradicated, at least becomes less of a threat to health.
(14) Loneliness (alpha = .885), higher for males than for females, was significantly correlated with various aspects of their high-school lives.
(15) To non-artists, there may not seem to be anything original or provocative about love, death, loneliness or cheese, either – yet gosh-darned artists keep finding new ways for humanity to look at them.
(16) Using hierarchical analysis of sets, the results indicated that the set of variables used to test the situational theory explained more variance in loneliness when entered first (62%) or second (34%) in the analysis than did the characterological set when entered first (33%) or second (5%) in the analysis.
(17) 'He was like me - desperate for ways to overcome his loneliness.'
(18) Social factors that can greatly reduce an elderly person's interest in food include loneliness, depression, isolation, and self-consciousness because of hearing and visual impairments.
(19) The charity network Acevo, which set up The Loneliness Project last year to tackle social isolation among young people in London, today publishes a report which suggests young Londoners are twice as likely to be lonely as their counterparts elsewhere in the country.
(20) In the thrall of social media and smartphones, we are drip-fed a steady supply of Instagram-filtered intimacy – and in this world, negative emotions and loneliness are taboo.