(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Newfoundland
Definition:
(n.) An island on the coast of British North America, famed for the fishing grounds in its vicinity.
(n.) A Newfoundland dog.
Example Sentences:
(1) The reported prevalence and severity of primary spheroidal degeneration in Labrador and nothern Newfoundland is based on a survey of 929 patients.
(2) This study reveals that gastric cancer mortality is high, by international comparisons, in Newfoundland, but is less than in the highest risk countries (Japan, Chile, Iceland).
(3) Tonsil size and serum immunoglobulin (G, A, M and D) measurements were studied in 1049 individuals during a health survey on the West Coast of Newfoundland.
(4) These cases occurred predominantly in Quebec (43%) followed by Alberta, British Columbia, Ontario, Saskatchewan, Manitoba, New Brunswick and Newfoundland.
(5) The charts of 310 consecutive patients with snowmobile injuries admitted to Charles S. Curtis Memorial Hospital, St. Anthony, Newfoundland, during the years 1969 through 1986 were reviewed in order to determine the causes and possible ways of prevention of these injuries.
(6) Using the population of St John's, Newfoundland, we did a constructive replication of previous studies testing the association between health practices and health status.
(7) Some indication is given of the frequency of the condition in Northern Newfoundland and Labrador.
(8) Nine specimens of the corneas of patients from Labrador and Northern Newfoundland affected by spheroidal degeneration (climatic droplet keratopathy) have been examined microscopically.
(9) Elevated prevalences of recessive disease, due primarily to matings between persons unaware of their distant consanguinity, therefore require consideration in health care planning in Newfoundland.
(10) The potential of Sarcocystis in caribou as a food-borne disease organism in man cannot be overlooked in view of its prevalence in meat and its widespread consumption, when lightly cooked, in rural Newfoundland.
(11) The distribution of arterial blood pressure (BP) values of 1499 adult inhabitants of four Newfoundland communities was surveyed.
(12) Coliform colony-forming units in sewage-contaminated seawater were observed to decrease rapidly with time in water that was collected from St. John's Harbour, Newfoundland, and isolated in dialysis bags; this confirms observations made in warmer climates.
(13) Cartographic plotting and correlation analyses of 23 individual or combined regions of Newfoundland with respect to M, F or M + F mortality rates showed a close similarity between high risk areas and large seabird aggregations which were in the southeast region of the island.
(14) The survey data were derived from all 1985 and 1986 deaths in the province of Newfoundland.
(15) The medical records of a Newfoundland general hospital for 1975 showed 2797 births, with women under 20 accounting for 13% of them.
(16) This study investigated suicides by people aged ten to 19 in Newfoundland and Labrador from 1977 to 1988.
(17) Speaking to the crowd, Syed Pirzada of the Muslim Association of Newfoundland and Labrador said the Muslim community had been overwhelmed by the outpouring of support they had received in recent days.
(18) Myocardial fiber disorganization and asymmetric septal hypertrophy, two other findings observed in patients with hypertrophic cardiomyopathy, were absent in each of the eight Newfoundland dogs with discrete subaortic stenosis.
(19) Ninety-eight members of a large Newfoundland family, seven of whose members over three generations suffered from Graves' disease, were studied with respect to the mode of transmission of the disease and its association with HLA.
(20) All its research notwithstanding, UNPERU expressed as much shock as the rest of the world when, over a year after the Ocean Ranger's visit, up from the still-recovering Newfoundland ground into which it had pushed its drill, the first clutch of newly-hatched oil rigs had unburied themselves.