What's the difference between disposition and orientation?

Disposition


Definition:

  • (n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
  • (n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
  • (n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
  • (n.) Conscious inclination; propension or propensity.
  • (n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
  • (n.) Mood; humor.

Example Sentences:

  • (1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
  • (2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
  • (3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
  • (4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
  • (5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
  • (6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
  • (7) Avoidance coping was negatively related to dispositional optimism.
  • (8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
  • (9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
  • (10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
  • (11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
  • (12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
  • (13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
  • (14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
  • (15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
  • (16) This paper reviews their pharmacologic disposition in man.
  • (17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
  • (18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
  • (19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
  • (20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.

Orientation


Definition:

  • (n.) The act or process of orientating; determination of the points of the compass, or the east point, in taking bearings.
  • (n.) The tendency of a revolving body, when suspended in a certain way, to bring the axis of rotation into parallelism with the earth's axis.
  • (n.) An aspect or fronting to the east; especially (Arch.), the placing of a church so that the chancel, containing the altar toward which the congregation fronts in worship, will be on the east end.
  • (n.) Fig.: A return to first principles; an orderly arrangement.

Example Sentences:

  • (1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
  • (2) With respect to family environment, a history of sexual abuse was associated with perceptions that families of origin had less cohesion, more conflict, less emphasis on moral-religious matters, less emphasis on achievement, and less of an orientation towards intellectual, cultural, and recreational pursuits.
  • (3) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
  • (4) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
  • (5) We have examined the initial events in myelin synthesis, including the insertion and orientation of PLP in the plasma membrane, in rat oligodendrocytes which express PLP and the other myelin-specific proteins when cultured without neurons (Dubois-Dalcq, M., T. Behar, L. Hudson, and R. A. Lazzarini.
  • (6) Other fusiform cells of the cPVN are oriented in a rostral-caudal plane and are situated more medially in this subdivision.
  • (7) During the interview process, nurse applicants frequently inquire about the availability of such a program and have been very favorably impressed when we have been able to offer them this approach to orientation.
  • (8) The central part of the system is the patient-orientated data bank.
  • (9) To alleviate these problems we developed an object-oriented user interface for the pipeline programs.
  • (10) Our data support the hypothesis that evoked and epileptiform magnetic fields result from intradendritic currents oriented perpendicular to the cortical surface.
  • (11) It’s gender, age, disability, sexual orientation, social background, and – most important of all, as far as I’m concerned – diversity of thought.” Diversity needs action beyond the Oscars | Letters Read more He may have provided the Richard Littlejohn wishlist from hell – you know the one, about the one-legged black lesbian in a hijab favoured by the politically correct – but as a Hollywood A-lister, the joke’s no longer on him.
  • (12) The changes are necessary to produce confident, supportive community oriented nurses.
  • (13) Families were randomly assigned to one of two forms of conjoint therapy: an Insight-oriented treatment (N = 10) or a Problem-Solving intervention (N = 10).
  • (14) Proper maintenance of body orientation was defined to be achieved if the net angular displacement of the head-and-trunk segment was zero during the flight phase of the long jump.
  • (15) In conjunction with the development of a computerized goal-oriented record system at Forest Hospital Des Plaines, Illinois, research staff developed a psychiatric goal list from goal statements most frequently used at the hospital.
  • (16) Given the liberalist context in which we live, this paper argues that an act-oriented ethics is inadequate and that only a virtue-oriented ethics enables us to recognize and resolve the new problems ahead of us in genetic manipulation.
  • (17) A team-oriented problem-solving procedure using management project teams was developed to improve quality of care and productivity in a private, nonprofit hospital.
  • (18) Orientation and lever responding were not functionally related.
  • (19) Circular dichroism (CD) spectra indicating different local orientation of oxazolone, when coupled to L or D side chain-terminating amino acids, support this suggestion.
  • (20) Economic burdens for postmarketing research should be shared jointly by the research-oriented and generic drug companies.