(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Outlook
Definition:
(v. t.) To face down; to outstare.
(v. t.) To inspect throughly; to select.
(n.) The act of looking out; watch.
(n.) One who looks out; also, the place from which one looks out; a watchower.
(n.) The view obtained by one looking out; scope of vision; prospect; sight; appearance.
Example Sentences:
(1) It would be fascinating to see if greater local government involvement in running the NHS in places such as Manchester leads over the longer term to a noticeable difference in the financial outlook.
(2) With an increased understanding of the fundamental biologic characteristics of brain tumors, we should be able to improve the outlook for these patients.
(3) Moreover, the possibility that the situation in Europe will worsen further remains a significant risk to the outlook.
(4) Hopes that the Queen's diamond jubilee and the £9bn spent on the Olympics would lift sales over the longer term have largely been dashed as growth slows and the outlook, though robust with a growing order book, remains subdued.
(5) Yet the OBR’s list of basic assumptions in its 260-page report on the economic and fiscal outlook this week are not exactly controversial: the UK to leave the EU in 2019; slower import and export growth in the transitional period; a tighter migration regime.
(6) Chris Williamson, of data provider Markit, said: "A batch of dismal data and a gloomier assessment of the economic outlook has cast a further dark cloud over the UK's economic health, piling pressure on the government to review its fiscal policy and growth strategy.
(7) The study says: "The short-term outlook for the labour market looks bleak.
(8) McCall said the outlook remained uncertain: “The economic and operating environment remains uncertain, following the high levels of disruption and more recently the UK’s referendum decision to leave the EU, as well as the recent events in Turkey and Nice, which have affected consumer confidence.
(9) The author then describes new approaches to improving the vocational integration of persons with epilepsy, by focussing on the one hand on extending the range of occupational assessment, and the adoption of new job placement assessment, and the adoption of new job placement strategies on the other, which concurrently seek to influence those factors that are detrimental to the occupational outlook of the person with a seizure disorder (notably frequent seizures, psychiatric problems, low educational levels, negative employer attitudes).
(10) The IMF itself came under fire after it admitted in its World Economic Outlook report that officials had underestimated the effects of austerity measures on economic growth.
(11) Christine Lagarde, the IMF’s managing director, has made it plain that another downgrade is anticipated when the Washington-based organisation publishes its World Economic Outlook next week.
(12) When the critical early period, which still carries a high mortality, has been passed, the outlook is relatively favourable.
(13) The City regulator also used its Prudential Risk Outlook to reveal that the UK's biggest banks have been told they must have enough capital to withstand a plunge back into recession in the next four years.
(14) The "lock-in" effect is the single most important factor increasing the danger of runaway climate change, according to the IEA in its annual World Energy Outlook, published on Wednesday.
(15) It appears that the administration of rhGM-CSF allows this high-dose regime of chemotherapy to be given safely and the early encouraging response rate adds support to the concept that increasing the dose of doxorubicin improves the outlook for patients with advanced soft-tissue sarcomas.
(16) It is concluded that the heretofore pessimistic outlook regarding complete quadriplegia is unwarranted and that a more aggressive approach may result in a better functional outcome.
(17) Signs that large companies are ready to start spending some of the cash piles they have been sitting on while smaller firms are prepared to borrow to expand reflect a brighter outlook for sales.
(18) It would be a mistake to rush it.” But, while revealing disappointing trading figures for the Christmas period and a gloomy outlook for 2017 , Wolfson said he did not think Brexit jitters were stopping people from shopping: “It is more the fact that incomes are likely to be squeezed.” Next's gloomy 2017 forecast drags down fashion retail shares Read more Wolfson was one of a handful of senior business leaders to openly back Brexit but has said in the past that the referendum vote was about UK independence, not isolation, and the country should be aiming for “an open, global-facing economy”.
(19) In what is being hailed as one of the first tangible signs in a change of outlook for Greece, the European Investment Bank has also agreed to inject up to €750m into the cashed-starved Greek economy with immediate effect.
(20) An outlook is given on the contemporary theories referring to the role of copper in nutrition.