(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Phlegmatic
Definition:
(a.) Watery.
(a.) Abounding in phlegm; as, phlegmatic humors; a phlegmatic constitution.
(a.) Generating or causing phlegm.
(a.) Not easily excited to action or passion; cold; dull; sluggish; heavy; as, a phlegmatic person.
Example Sentences:
(1) This zoophilic dermatophyte may cause a difficult human phlegmatic trichophytia infection.
(2) In conditions of conflict between probability and value of reinforcement the dogs manifested two opposite strategies of behaviour: orientation to highly probable events (choleric and phlegmatic) and to low-probable events (sanguinic and melancholic) what is connected with individual properties of functioning and the character of interaction of four brain structures (frontal cortex, hippocampus, hypothalamus, amygdala).
(3) Rosberg, it seems, has resigned himself to the more phlegmatic tactic of doing his considerable best while hoping that Hamilton implodes.
(4) Cypriots are phlegmatic in a way their more hot-blooded Greek neighbours are not.
(5) If that means you’re not going to vote for me, well I’ve had my career, but I want to do what I think is the right thing, and if that means it costs me votes, it costs me votes.” Three decades in the police has had the added advantage of making him “phlegmatic” about his posters being repeatedly vandalised, he adds cheerfully.
(6) Surely murdering children at a pop concert should set these useless phlegmatic Brits’ blood boiling?
(7) A phlegmatic person is characterised by a lack of egoistic or altruistic instincts while feelings of nausea or fear are increased.
(8) While Brandon Lewis, Tory MP for Great Yarmouth, whose constituency includes the Hemsby area, pledged to help residents fight for more funds for coastal defence, some people were remarkably phlegmatic about the storm.
(9) The chancellor knew that Britain's biggest bank was in trouble even before McKillop came on the line, yet even the normally phlegmatic Darling was surprised at the size and immediacy of the crisis.
(10) That was why, he explained, Welshmen were put in charge instead of "the bovine and phlegmatic Anglo-Saxons."]
(11) Lebedev, a semi-opposition figure, was phlegmatic about his defeat, telling the Guardian: "My campaign lasted for three days."
(12) Even phlegmatic Germany had a post World Cup hangover; in an environment as emotionally volatile as South Africa, it's inevitable.
(13) Welby is said to be phlegmatic about the prospect, believing he has done everything possible to offer the opportunity to forge a new, looser relationship, which hardliners may choose to reject.
(14) One of the few to take the turn of events phlegmatically was Johnson’s father, Stanley, who said the appropriate phrase was “Et tu, Brute?” before going on to say he now thought Gove was the best choice.
(15) The 57-year-old surgeon from Glasgow, who had been booked on a flight yesterday anyway, was phlegmatic about the whole affair.
(16) "If we need to go back over that stuff," says Ashley, resolute and phlegmatic, "our problems were from 10 years ago.
(17) You have to do the best by your child, don’t you?” is intoned with a phlegmatic sigh, lips pressed together in wry acknowledgment that the situation isn’t ideal, but life’s a bitch, and one’s own child’s interests – obviously– trump every other consideration.
(18) The oligarch said he didn't regret bringing the case, and even attempted a phlegmatic note, observing: "Life is life," before speeding off in a black Mercedes.
(19) All I’m doing is giving a pint of blood over six months.” Ruth Atkins, an NHS communications manager and former nurse from Oxford, is similarly phlegmatic about her contribution.
(20) I thought of Georges Simenon’s curmudgeonly, phlegmatic detective, Chief Inspector Maigret.