(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Temper
Definition:
(v. t.) To mingle in due proportion; to prepare by combining; to modify, as by adding some new element; to qualify, as by an ingredient; hence, to soften; to mollify; to assuage; to soothe; to calm.
(v. t.) To fit together; to adjust; to accomodate.
(v. t.) To bring to a proper degree of hardness; as, to temper iron or steel.
(v. t.) To govern; to manage.
(v. t.) To moisten to a proper consistency and stir thoroughly, as clay for making brick, loam for molding, etc.
(v. t.) To adjust, as the mathematical scale to the actual scale, or to that in actual use.
(n.) The state of any compound substance which results from the mixture of various ingredients; due mixture of different qualities; just combination; as, the temper of mortar.
(n.) Constitution of body; temperament; in old writers, the mixture or relative proportion of the four humors, blood, choler, phlegm, and melancholy.
(n.) Disposition of mind; the constitution of the mind, particularly with regard to the passions and affections; as, a calm temper; a hasty temper; a fretful temper.
(n.) Calmness of mind; moderation; equanimity; composure; as, to keep one's temper.
(n.) Heat of mind or passion; irritation; proneness to anger; -- in a reproachful sense.
(n.) The state of a metal or other substance, especially as to its hardness, produced by some process of heating or cooling; as, the temper of iron or steel.
(n.) Middle state or course; mean; medium.
(n.) Milk of lime, or other substance, employed in the process formerly used to clarify sugar.
(v. i.) To accord; to agree; to act and think in conformity.
(v. i.) To have or get a proper or desired state or quality; to grow soft and pliable.
Example Sentences:
(1) To become president of Afghanistan , Ashraf Ghani Ahmadzai changed his wardrobe and modified his name, gave up coffee, embraced a man he once denounced as a “known killer” and even toyed with anger management classes to tame a notorious temper.
(2) No definite relationship could be established between the biochemical reactions and the flagellar antigens of the lysogenic strain and its temperate phage though some temperate phages released by E. coli O119:B14 strains with certain flagellar antigens did give specific lytic patterns and were serologically identical.
(3) It begins with the origins of treatment in the self-help temperance movement of the 1830s and 1840s and the founding of the first inebriate homes, tracing in the United States the transformation of these small, private, spiritually inclined programs into the medically dominated, quasipublic inebriate asylums of the late 19th century.
(4) A temperate phage was induced from exponential phase cells of Erwinia herbicola Y46 by treatment with mitomycin C. The phage was purified by single plaque isolation, and produced in bulk by successive cultivation in young cultures of E. herbicola Y 178.
(5) A truncated form of the HBL murein hydrolase, encoded by the temperate bacteriophage HB-3, was cloned in a pUC-derivative and translated in Escherichia coli using AUC as start codon, as confirmed by biochemical, immunological, and N-terminal analyses.
(6) Group II (21%) included virulent and temperate phages with small isometric heads.
(7) Diagnostic methods which reveal only the presence or absence of Ostertagia in grazing animals are of little importance since all will acquire some degree of infection when grazed in the temperate regions of the world.
(8) Recently, methods have been developed to distinguish between human and animal faecal pollution in temperate climates.
(9) The recent enthusiasm for the combined Collis-Belsey operation should be tempered by continued, cautious, objective assessment of its long-term results.
(10) These differences in susceptibility are due, in part, to immunity imposed by temperate phages carried by the different strains.
(11) Therefore, production of turimycin is not controlled by the isolated temperate phage.
(12) On at least three independent occasions a 1.6 kb segment of Streptomyces coelicolor DNA was detected in apparently the same location in an attP-deleted derivative of the temperate phage phiC31 that carried a selectable viomycin resistance gene.
(13) These results indicated that gender tempers the effect of family type on adolescent adjustment.
(14) However, its use must be tempered with an appreciation of the limitations of the new technique and knowledge of the circumstances in which it may yield erroneous results.
(15) The infection of Bacillus thuringiensis, B. cereus, B. mesentericus and B. polymyxa strains with temperate E. coli bacteriophage Mu cts62 integrated into plasmid RP4 under conditions of conjugative transfer is shown possible.
(16) As newer techniques are developed, it is mandatory that the application of these techniques be tempered with controlled clinical trials, documenting their effectiveness.
(17) Such lesions are quite common in subtropical and tropical climates, and a review of the literature indicates that the incidence of this formerly rare entity is increasing in temperate climates.
(18) Calculated values of residual compressive stress for tempered specimens were considerably higher than those for specimens that were slowly cooled and those that were cooled by free convection.
(19) Three sedentary men underwent a 3-mo period of endurance training in a temperate climate, (dry bulb temperature (Tdb): 18 degrees C) and had their sweating sensitivity measured before and after the training period.
(20) This level of susceptibility is higher than that found in most temperate countries and mainland populations, and similar to descriptions in a few island and rural populations in the tropics.