(n.) The act of disposing, arranging, ordering, regulating, or transferring; application; disposal; as, the disposition of a man's property by will.
(n.) The state or the manner of being disposed or arranged; distribution; arrangement; order; as, the disposition of the trees in an orchard; the disposition of the several parts of an edifice.
(n.) Tendency to any action or state resulting from natural constitution; nature; quality; as, a disposition in plants to grow in a direction upward; a disposition in bodies to putrefaction.
(n.) Conscious inclination; propension or propensity.
(n.) Natural or prevailing spirit, or temperament of mind, especially as shown in intercourse with one's fellow-men; temper of mind.
(n.) Mood; humor.
Example Sentences:
(1) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(2) Models of the VMT nuclei were constructed to compare their size, shape and disposition across species.
(3) These marked steroid-induced changes in MS responsiveness could not be explained by altered pharmacokinetic disposition of morphine.
(4) The disposition of sulphadimidine (15 mg kg-1 orally) was investigated in six chronic osteoarthritis patients (four slow and two fast acetylators) prior to and 4 days following intra-articular administration of glucocorticoids.
(5) In the present paper, attention has been focused on the role of cytokines and the effects of the acute phase response on drug disposition in disease states (including the effect of anorexia on medicated feed intake and drug bioavailability).
(6) The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si).
(7) Avoidance coping was negatively related to dispositional optimism.
(8) The greatest problems appeared in diagnosing thrombosis of mesenterial vessels and acute appendicitis in cases with the retrocecal disposition of the vermiform process.
(9) Awareness of making dispositional inferences was only weakly correlated with disposition-cued recall.
(10) Current methods of evaluating the bioavailability of drugs with nonlinear disposition kinetics are based on specific pharmacokinetic models in contrast to the more rational model independent (structureless) area under the curve (AUC) and deconvolution methods used in linear pharmacokinetics.
(11) The disposition profiles of a new beta-adrenergic blocking drug, timolol, were investigated at 11 different times in normal individuals after a single oral dose.
(12) In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h.
(13) Leukocyte differentials from 468 emergency room patients were assessed for clinical value by determining their associations with diagnosis, disposition, therapy, and prognosis.
(14) To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose concentration also improves the postprandial pattern of glucose disposition, glucose metabolism after ingestion of a solid mixed meal was assessed in obese patients with NIDDM before and after treatment with ultralente and compared with glucose metabolism observed in nondiabetic subjects.
(15) Particular emphasis was placed on the relative spatial disposition of the tyramine moiety and the additional aromatic ring that occurs in both molecules.
(16) This paper reviews their pharmacologic disposition in man.
(17) The effects of modulation of liver microsomal sulphoxidation on the disposition kinetics of netobimin (NTB) metabolites were investigated in sheep.
(18) The changes in physicochemical properties due to introduction of a benzenesulfonyl group into the hydantoin ring may be responsible for the difference in the disposition between I and II.
(19) The disposition of amiloride was highly dependent on renal function, with higher plasma amiloride concentrations in the elderly reflecting diminished renal function.
(20) The clinical significance of the altered disposition of chloramphenicol is that administration at the usual dosing rate would lead to accumulation of the drug and eventual toxicity.
Wickedness
Definition:
(n.) The quality or state of being wicked; departure from the rules of the divine or the moral law; evil disposition or practices; immorality; depravity; sinfulness.
(n.) A wicked thing or act; crime; sin; iniquity.
Example Sentences:
(1) But just as Oliver Stone has managed to make a boring sequel to Wall Street, despite the real Wall Street's enthralling and nigh-on-cinematic recent wickedness (the inner Freudian torment of boring Shia LaBoeuf's boring character is apparently more interesting to Stone – once the great purveyor of conspiracy theories – than the near-collapse of capitalism), so the makers of the upcoming films about Facebook have missed an obvious trick with their movies.
(2) Tony Abbott has recently delivered an explicit warning that the Daesh death cult is “coming for us”, however, Turnbull argued it was important not to get sucked into the Isis strategy “and ourselves become amplifiers of their wickedness and significance”.
(3) It is towards an anti-government fervour that recalls the militia movement of the 1990s, convinced that every Washington move – even a plan to expand healthcare – is motivated by wickedness and constitutes a step towards tyranny.
(4) Less welcome was Professor Griff's 1989 interview with the Washington Times where he condemned Jews as responsible for 'the majority of the wickedness that goes on across the globe'.
(5) Facebook Twitter Pinterest Video: Volkswagen chief executive Martin Winterkorn resigns, taking responsibility for the German carmaker’s rigging of US emissions tests Yet it would be simplistic to blame the wickedness of the industry and to suppose that the consumers involved were entirely innocent idealists, cruelly misled by unscrupulous marketeers.
(6) I know we are supposed to present them as extreme wickedness but they don’t appear like that to lots of Labour voters who thought this was mainstream Labour policy.
(7) There is a certain perverse charm to what appears to be Sepp’s final mission: exposing the weaknesses and wickedness of everyone who has profited from his regime down the decades.
(8) Maybe that’s because Laurie’s Roper has been enter taining us for so long with his cool, his wit, his urbanity and his sheer wickedness that we don’t want to let him go.
(9) They lament western wickedness with the reliability of professional mourners.
(10) Before tragedy strikes, we must all take the initiative and talk to these families, listen to their problems but, ultimately, we must take proactive steps to help them before "hate" and "wickedness" take a hold.
(11) We now know the banks' tricks involved not just dubious wizardry but a measure of wickedness too.
(12) Alice Morgan – said patricidal psychopath, played with delicious wickedness by Ruth Wilson – is one of TV's most unusual sidekicks.
(13) When I asked my friend the professor of gender studies about all this stuff some time ago (I know this sounds like the overture to a joke, but it isn't), I was semi-secretly hoping for a jeremiad on the wickedness of princess-mania, and tips on how she'd saved her daughters from it.Actually, she said, one of hers had that obsession too, for a bit – but that other obsessions came along to supplant them.
(14) This warning about the lure of wickedness reveals how Prince’s vision of the battle between good and evil was much darker than Burton’s take.
(15) When the full extent of his wickedness was revealed, we put him in a box marked "monster".
(16) Just as some were putting the wickedness of Savile and his ilk in a box marked “long ago”, Rochdale broke and the abuse of children in care was revealed.
(17) Under the amendment the same buildings, the same canteen, the same umbrella stands, the same courses, the same bitching about Orbán and his wickedness can continue, and students can get a qualification recognised in Europe .
(18) Stories such as the prime minister’s surprisingly resilient support for the charity, the lobbying of a Conservative party co-treasurer – James Lupton – and the embedding of two civil servants to help restructure the organisation somehow became examples of the wickedness that had taken root in the charity.
(19) What many people seem to want is to be confirmed in their view that all of this is down to the personal wickedness of a single individual; arrest Blair, clap him in irons at The Hague, and everything will return to a state of primal, unsullied innocence.
(20) The virtue of Israel and the wickedness of her enemies are recurring themes in his work."