(a.) Loosed from restraint; esp., loose in morals and conduct; recklessly abandoned to sensual pleasures; profligate; wanton; lewd; debauched.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A 2-fold increase in the dissolution rate was observed when the same number of particles was immobilized without macrophages.
(3) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
(4) At 30 days after injection both stains revealed cellular debris and glial reactions characteristic of cellular dissolution.
(5) The in vitro dissolution study carried out using dynamic dialysis revealed that the release of adriamycin from these particles follows a bi-phasic pattern.
(6) The retreating rate constants deduced from the dissolution results were well coincident with the values directly determined by the needle penetration method, suggesting good applicability of the proposed equation.
(7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
(8) Instead, a repetitive, stepwise dissolution pattern was observed.
(9) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
(10) Reductions in dissolution rates in a continuous-flow system could best be interpreted by assuming that they reflected changes in the area of the hydrophilic solid exposed to the solvent.
(11) Applications from Serbia, which account for 10% of the total, stem mostly from the dissolution of former Yugoslavia: payment of army reservists, access to savings in present-day Bosnia and Herzegovina, pensions in Kosovo.
(12) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
(13) The differences in the amounts of rapidly releasable calcium were attributed to different kinetics of calcium phosphate and calcium oxalate dissolution.
(14) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
(15) Two commercial slow-release potassium chloride tablets, Slow-K and Addi-K have the characteristics of slow-release in the different dissolution conditions.
(16) Two consequences of these conditions are (1) patient classification into syndrome types (e.g., phonological dysgraphia, agrammatism, and so forth) can play no useful role in research concerned with issues about the structure of normal cognitive functioning or its dissolution under conditions of brain damage; and (2) only single-patient studies allow valid inferences about the structure of cognitive mechanisms from the analysis of impaired performance.
(17) Areas suggestive of cellular dissolution and disorganization were also reported in experimental parathyroids
(18) Speaking in Adelaide on Thursday as the government struggles to turn around its polling in South Australia before a possible double dissolution election, the prime minister went on the attack and said Labor was making major policy announcements on the fly.
(19) Although all three formulations were shown to have similar dissolution profiles, dissolution of chlorpropamide was pH-dependent in vitro.
(20) However, if solubility is considered as a function of pH at equilibrium, i.e., the final pH after the dissolution products have entered the solvent--a model more akin to the in vivo situation--hydroxyapatite is the conspicuously more soluble of the two minerals.
Hedonic
Definition:
(a.) Pertaining to pleasure.
(a.) Of or relating to Hedonism or the Hedonic sect.
Example Sentences:
(1) It may have been like punk never ‘appened, but you caught a whiff of the movement’s scorched earth puritanism in the mocking disdain with which Smash Hits addressed rock-star hedonism.
(2) When the amount of intake was described in terms of an hedonic index (HI), which indicates the hedonic aspect of the taste of each solution, HI's for sucrose, NaCl, HCl, and quinine were 1.17, 0.43, -0.49, and -0.89, respectively.
(3) These results indicate that quantification of effects of hedonic ratings on intake within subjects is possible, but that hedonic ratings may not be good discriminators of intake differences between subjects.
(4) Forty-two chronic schizophrenic patients were evaluated for extent of hedonic deficit and compared with a demographically matched sample of normals.
(5) The excitatory potential, the involvement potential, and the hedonic valence of the nonerotic and erotic stimuli were also assessed.
(6) To determine the contribution of sensory stimulation to the changing hedonic response to foods, the effects of consuming very low-calorie and higher calorie versions of soup and jello on the subjective pleasantness of foods were compared.
(7) The responses to salty, sour, and bitter solutions shared the same hedonically negative upper- and midface components but differed in the accompanying lower-face actions: lip pursing in response to sour and mouth gaping in response to bitter.
(8) The results suggest that the increased desire to binge in response to stressors reported by subjects higher in disordered eating cannot be accounted for by differences in cardiovascular reactivity or negative hedonic state, relative to what subjects low in disordered eating showed in response to the same stressors.
(9) Another was to escape into a world of desperate hedonism.
(10) Of course there was, and still is, wild hedonism among some of the more flamboyant and brash members of the trading community, but focusing on the outliers is no way to properly judge the majority of the industry.
(11) Our data include measures of: (1) psychological functioning of the parents; (2) the environment, including family functioning, marital adjustment, and parenting practices; (3) child adjustment, including peer, or teacher, parent, and self-ratings; (4) early signs or precursors to the development of schizophrenia or affective disorder, including cognitive slippage, attentional deficits, hedonic capacity, depressogenic attributional styles, and subsyndromal affective patterns.
(12) The inter-relationship of personality with dietary intake of salt and sugar, and with hedonic responses to saltiness and sweetness, was examined among 62 female and 38 male university students.
(13) Dynorphin A(1-8) activity within some brainstem structure(s) may therefore contribute prominently to the opioid mechanism whose mediation of the hedonic response to food was previously inferred from naloxone antagonism.
(14) Alterations in CTA learning and extinction following lesions of the lateral tegmental noradrenergic system appear to reflect alterations in the way that animals with lesions react toward the hedonic aspects of taste-related stimuli rather than alterations in associational or attentional mechanisms.
(15) Audio-taped interviews recorded in the Gottesman-Shields schizophrenic twin series (17 pairs of identical twins, 14 pairs of fraternal same-sex twins, and 12 unpaired twins) were rated for level of hedonic capacity.
(16) Mice selectively bred for sensitivity (COLD) or insensitivity (HOT) to the hypothermic effect of ethanol were tested in three tasks purported to assess ethanol's hedonic properties: place conditioning, taste conditioning, and ethanol drinking.
(17) Hedonic capacity was found to be genetically influenced, although it appeared to be less heritable than the global diagnosis of schizophrenia.
(18) Only with regard to androstenone did trend analyses reveal a significant quadratic relationship between hedonic estimates and phases of the menstrual cycle, peaking at ovulation.
(19) Intensity and hedonic responses were collected using an unstructured linear scale and a nine-point interval scale, respectively.
(20) Morphine reduced the aversive hedonic properties of both novel and familiar quinine solution (0.05% and 0.1%) but did not modify the palatability of 20% sucrose solution.