(a.) Loosed from restraint; esp., loose in morals and conduct; recklessly abandoned to sensual pleasures; profligate; wanton; lewd; debauched.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A 2-fold increase in the dissolution rate was observed when the same number of particles was immobilized without macrophages.
(3) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
(4) At 30 days after injection both stains revealed cellular debris and glial reactions characteristic of cellular dissolution.
(5) The in vitro dissolution study carried out using dynamic dialysis revealed that the release of adriamycin from these particles follows a bi-phasic pattern.
(6) The retreating rate constants deduced from the dissolution results were well coincident with the values directly determined by the needle penetration method, suggesting good applicability of the proposed equation.
(7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
(8) Instead, a repetitive, stepwise dissolution pattern was observed.
(9) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
(10) Reductions in dissolution rates in a continuous-flow system could best be interpreted by assuming that they reflected changes in the area of the hydrophilic solid exposed to the solvent.
(11) Applications from Serbia, which account for 10% of the total, stem mostly from the dissolution of former Yugoslavia: payment of army reservists, access to savings in present-day Bosnia and Herzegovina, pensions in Kosovo.
(12) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
(13) The differences in the amounts of rapidly releasable calcium were attributed to different kinetics of calcium phosphate and calcium oxalate dissolution.
(14) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
(15) Two commercial slow-release potassium chloride tablets, Slow-K and Addi-K have the characteristics of slow-release in the different dissolution conditions.
(16) Two consequences of these conditions are (1) patient classification into syndrome types (e.g., phonological dysgraphia, agrammatism, and so forth) can play no useful role in research concerned with issues about the structure of normal cognitive functioning or its dissolution under conditions of brain damage; and (2) only single-patient studies allow valid inferences about the structure of cognitive mechanisms from the analysis of impaired performance.
(17) Areas suggestive of cellular dissolution and disorganization were also reported in experimental parathyroids
(18) Speaking in Adelaide on Thursday as the government struggles to turn around its polling in South Australia before a possible double dissolution election, the prime minister went on the attack and said Labor was making major policy announcements on the fly.
(19) Although all three formulations were shown to have similar dissolution profiles, dissolution of chlorpropamide was pH-dependent in vitro.
(20) However, if solubility is considered as a function of pH at equilibrium, i.e., the final pH after the dissolution products have entered the solvent--a model more akin to the in vivo situation--hydroxyapatite is the conspicuously more soluble of the two minerals.
Impudent
Definition:
(a.) Bold, with contempt or disregard; unblushingly forward; impertinent; wanting modesty; shameless; saucy.
Example Sentences:
(1) Yet it was still an encouraging victory for Mourinho’s team and a difficult afternoon for Tottenham Hotspur was probably summed up by the moment Dele Alli, the impudent young buck, tried to upstage Michael Carrick by slipping the ball through his opponent’s legs.
(2) Ozil is an impudent playmaker who usually flits behind the lone striker, finding space and creating opportunities with his sublime left foot.
(3) She says she saw the girls' "devilish twitching" and "committing impudences".
(4) Caballero could not keep out Emre Can’s impudent little pitch-wedge to get the penalties underway but thereafter he was unbeatable, diving to his left to turn away a decent attempt by Lucas Leiva, a hesitant one from Philippe Coutinho, and then the other way to beat out Adam Lallana’s effort for his third successive save.
(5) Henderson skied a glorious chance over from Sterling's pass and it needed an instinctive save from Lloris to prevent Sturridge scoring with an impudent back-heel.
(6) Robbing the Royal Mail was, as the trial judge, Mr Justice Edmund Davies, told Biggs , "a crime which, in its impudence and enormity, is the first of its kind in this country."
(7) The nutmeg from Messi left him on his backside and, high in the stands, Pep Guardiola could be seen with his head in his hands, howling with laughter at the impudence of his former player.
(8) The judge told them, as he sent them away for 30 years, that it was “a crime which in its impudence and enormity is the first of its kind in this country.
(9) Arsenal played at times as if it would have been impudent to trouble the Spaniard.
(10) Chelsea were stunned, almost into submission and when Lanzini, whose impudent touches and ease on the ball made him a delight to watch, carved them open with a delightful backheel, Aaron Cresswell would have made it 2-0 if Branislav Ivanovic had not deflected his effort past the left post.
(11) Both players scored within three minutes of one another and, however impudent it was for Mourinho to shake Ferguson's hand and set off for the dugout with the final exchanges of stoppage time still to be played, the truth is the game had already been won.
(12) New junior doctors' contract changes everything I signed up for Read more With sickness levels running at record levels, you would expect the government to act more sensitively and with less impudence.
(13) As a reward for my impudence, I was sent on my way with a pat on the shoulder, a "well done, son".
(14) He decorated a driving performance with an impudent nutmeg on Luka Modric.
(15) What kind of a union of partners treats one of its members like a recalcitrant colony, destroys its economy if it steps out of line, and dismisses its democracy as an impudent affront?
(16) Before being cut off by a prison official, Tolokonnikova said: "I hope they don't have the impudence to jail him – because, after all, he is even more of a media figure among the people than the members of Pussy Riot, at least in Russia .
(17) But instead of closing ranks and crushing this impudent upstart, Cameron and Brown fell over themselves to win his support.
(18) "It has become a symbol of women's freedom in western nations and with impudence they want to free her," the foreign ministry spokesman Ramin Mehmanparast protested last month.
(19) Add ingenious, impudent finishing and you have a footballer who truly quickens the pulse."
(20) Yet it is not so easy understanding why Rooney, playing so well in his new midfield role, needs to be rested (England’s next game would not be until Saturday at the earliest) and it is worth keeping in mind Slovakia beat Spain in qualifying and were impudent enough to win 3-1 when Germany invited them to Augsburg for a friendly a few weeks ago.