(a.) Loosed from restraint; esp., loose in morals and conduct; recklessly abandoned to sensual pleasures; profligate; wanton; lewd; debauched.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A 2-fold increase in the dissolution rate was observed when the same number of particles was immobilized without macrophages.
(3) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
(4) At 30 days after injection both stains revealed cellular debris and glial reactions characteristic of cellular dissolution.
(5) The in vitro dissolution study carried out using dynamic dialysis revealed that the release of adriamycin from these particles follows a bi-phasic pattern.
(6) The retreating rate constants deduced from the dissolution results were well coincident with the values directly determined by the needle penetration method, suggesting good applicability of the proposed equation.
(7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
(8) Instead, a repetitive, stepwise dissolution pattern was observed.
(9) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
(10) Reductions in dissolution rates in a continuous-flow system could best be interpreted by assuming that they reflected changes in the area of the hydrophilic solid exposed to the solvent.
(11) Applications from Serbia, which account for 10% of the total, stem mostly from the dissolution of former Yugoslavia: payment of army reservists, access to savings in present-day Bosnia and Herzegovina, pensions in Kosovo.
(12) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
(13) The differences in the amounts of rapidly releasable calcium were attributed to different kinetics of calcium phosphate and calcium oxalate dissolution.
(14) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
(15) Two commercial slow-release potassium chloride tablets, Slow-K and Addi-K have the characteristics of slow-release in the different dissolution conditions.
(16) Two consequences of these conditions are (1) patient classification into syndrome types (e.g., phonological dysgraphia, agrammatism, and so forth) can play no useful role in research concerned with issues about the structure of normal cognitive functioning or its dissolution under conditions of brain damage; and (2) only single-patient studies allow valid inferences about the structure of cognitive mechanisms from the analysis of impaired performance.
(17) Areas suggestive of cellular dissolution and disorganization were also reported in experimental parathyroids
(18) Speaking in Adelaide on Thursday as the government struggles to turn around its polling in South Australia before a possible double dissolution election, the prime minister went on the attack and said Labor was making major policy announcements on the fly.
(19) Although all three formulations were shown to have similar dissolution profiles, dissolution of chlorpropamide was pH-dependent in vitro.
(20) However, if solubility is considered as a function of pH at equilibrium, i.e., the final pH after the dissolution products have entered the solvent--a model more akin to the in vivo situation--hydroxyapatite is the conspicuously more soluble of the two minerals.
Profligate
Definition:
(a.) Overthrown; beaten; conquered.
(a.) Broken down in respect of rectitude, principle, virtue, or decency; openly and shamelessly immoral or vicious; dissolute; as, profligate man or wretch.
(n.) An abandoned person; one openly and shamelessly vicious; a dissolute person.
(v. t.) To drive away; to overcome.
Example Sentences:
(1) But this is not to say that I do not have a working knowledge of true bedsitters - and yes, they do still exist, in spite of estate agents' profligate use of the term 'studio flat'.
(2) But it relies too much on the myth that booms enrich everyone, a myth easily exposed by pointing out that under that supposedly profligate Labour administration, now accused of recklessly taking from the rich and giving to the poor, the gap between the richest and the poorest didn't narrow.
(3) "With a 53 per cent increase in energy consumption forecast by 2035, those who are commercially savvy will recognise that in a resource poor future, we cannot be captured by a profligate economic model from the past.
(4) Reasonable use” sounds … well, reasonable, but a “use it or lose it” clause incentivizes profligate use: if you don’t use your historic water allocation in a beneficial way, you forfeit your water rights, Gray said.
(5) The coalition succeeded an unbelievably profligate government that took state spending from 34% of GDP to over 45% in a decade .
(6) Other critics say low water prices are the culprits as they result in profligate water use and low investment in water-efficient infrastructure.
(7) All the debt ceiling ends up becoming is a political football used by the opposition party to suggest the government are profligate spenders.
(8) He believes that Osborne's decision to veto the measures in February shows that the Tories want to put spending cuts ahead of tackling child poverty as he seeks to depict Labour as profligate.
(9) The credit crunch hit, which might have been terminal to a project so palpably of the profligate boom years, but then the cavalry appeared, in the form of the property arm of the ruling family of Qatar.
(10) Thatcherism liked to present itself as a rejection of the postwar, state-driven, more profligate way of doing things.
(11) There is no reason why a constitutional solution that involves debt limitation should not command a large measure of public acceptance, especially in debtor countries, which have experienced the political and economic damage caused by previous profligate governments.
(12) In Brussels, right-of-centre German economists, who until recently dominated the European Central Bank's main decision-making board, lobbied for a "can't-pay, won't-pay" stance towards southern European countries seen as profligate spenders who need to understand the moral hazard of raising their living standards on a mountain of debt.
(13) The latest shock wave has served to ram home the reality that this remains first of all a crisis of the banks and the private sector – not, as the British government would have it, of profligate governments and public debt, which only ballooned to fill the gap left by market failure.
(14) Election officials have also disqualified Raja Pervaiz Ashraf, the man who until just a few weeks ago was the country's prime minister, under articles ensuring candidates are, among many other things, "sagacious, righteous and non-profligate".
(15) As inspectors from Brussels demanded answers this week from the Spanish government about how it plans to bring profligate regional governments under control, senior officials admitted they were clueless as to the real size of the debt in the biggest region – party-loving Andalucía.
(16) "People have far more confidence in Britain than in many other western countries who have got into trouble through profligate economic policies," he said.
(17) London, which has less annual rainfall than cities such as Athens and Sydney, is classed as "seriously water-stressed" by the Environment Agency , but critics of the Beckton plant – including former mayor of London Ken Livingstone – told the inquiry that desalination was energy-profligate, unnecessary and unsustainable.
(18) More and more people feel the gap between the profligate promises of individual freedom and sovereignty, and the incapacity of their political and economic organisations to realise them.
(19) His party has no members of parliament, a situation unlikely to change at the next election, and offers promiscuous and profligate policies that add up to errant nonsense as a platform for government.
(20) That debacle shows the Conservatives as being as profligate as sailors on shore leave.