(a.) Separated; having an intervening space; at a distance; away.
(a.) Far separated; far off; not near; remote; -- in place, time, consanguinity, or connection; as, distant times; distant relatives.
(a.) Reserved or repelling in manners; cold; not cordial; somewhat haughty; as, a distant manner.
(a.) Indistinct; faint; obscure, as from distance.
(a.) Not conformable; discrepant; repugnant; as, a practice so widely distant from Christianity.
Example Sentences:
(1) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(2) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The stage of a given malignancy, representing the degree of spread of the tumor to its local surroundings or distant sites, is the best predictor of long-term survival.
(5) Seven patients died, six because of distant metastases within one year.
(6) Local or distant metastases presented in 6 patients.
(7) His office - with a floor-to-ceiling glass wall offering views over a Bradford suburb and distant moors - is devoid of knick-knacks or memorabilia.
(8) Generally, more distant neurones (500-1300 microns) were excited for variable periods of time (3-15 min), while neurones in the vicinity of the injection site (0-500 microns) showed, after a brief period of excitation time, a long-lasting (up to 30 min) decrease in excitability or silencing of discharge, probably due to a depolarizing block and disturbances in the ionic composition of the extracellular space.
(9) Using the Italian I distantly remember from my year abroad in Florence as a student (mi chiama Hadley!
(10) The national study accrued 216 patients with measurable or evaluable non-small cell lung cancer (NSCLC) with either unresectable stage III, or distant metastasis (stage IV).
(11) The special advantage of the UV-beam is that it allow to inactivate selectively of the particular elements of nuclear apparatus of living ciliates is to observe consequences of operation on distant descendants of irradiated cell.
(12) Although a high rate of local control can be expected, distant metastases continue to be a problem.
(13) Indeed, the geographical nature of the division also keeps a check on the club's carbon footprint – Dartford rarely have to travel far outside the M25, with the trips to Bognor Regis and Margate about as distant as they get.
(14) Concomitant immunity (CI) is defined as the lack or retardation or proliferation of a secondary tumor implant at a distant site; it has been given an immunological interpretation.
(15) Children with osteosarcoma or Ewing's sarcoma rarely have bone disease distant from the site of their primary bone lesion at presentation.
(16) The effect of combined treatment was studied in 97 patients with nonseminomatous testicular tumors with regional and distant metastases with regard to the blood serum levels of alpha-fetoprotein and chorionic gonadotropin.
(17) At diagnosis, 15 (16.5%) patients had regional metastases and six (7%) had distant metastases.
(18) The PPi-dependent Pfk of potato is only distantly related to the ATP-dependent enzymes.
(19) Sequences homologous to Inp are present in multiple copies in the N. plumbaginifolia and the N. tabacum genome but not in more distant species.
(20) Local or regional recurrence without evidence of distant metastases was identified in 11 per cent of cases after 'curative' resections.
Uninvolved
Definition:
Example Sentences:
(1) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
(2) The posterior retina remained uninvolved, and no further treatment was needed.
(3) Radiographs were taken with bones placed in up to four of the common sites of impaction and assessed on two occasions independently by two previously uninvolved ENT consultants.
(4) These results indicate that uninvolved psoriatic epidermis has an increased capacity to metabolize free AA into 12-lipoxygenase products.
(5) Involved and uninvolved psoriatic epidermal cells showed a fourfold decrease in the number of 12-HETE binding sites as compared with normal healthy individuals and patients with atopic dermatitis, while receptor affinity remained unchanged.
(6) Two neoplastic salivary glands had well-described, encapsulated tumors which showed reduced peroxidase activity when compared with the normal uninvolved portion.
(7) In chronic widespread dermatoses, the uninvolved skin is at least physiologically abnormal.
(8) Basic physiological characteristics were examined in the uninvolved skin of 39 patients with hand eczema and in 39 healthy controls.
(9) However, cytotoxic activity against autologous tumor cells exerted by cultured tumor-infiltrating lymphocytes was found to be significantly higher than the activity of cultured lymphocytes isolated from peripheral blood or uninvolved lung tissue of the same patient.
(10) Activities of two sulfotransferases toward galactosyl ceramide and lactosylceramide as substrates were significantly elevated in the renal cell carcinoma compared to the uninvolved, endorsing enhanced synthesis of the two sulfatides in the renal cell carcinoma.
(11) Flexion of the knee during stance was qualitatively different in the involved extremity as compared with the uninvolved extremity in all patients.
(12) The area of fluorescence seen around each capillary at 60 s was greater in plaque (P less than 0.001) and in uninvolved psoriatic skin (P less than 0.001) than in normal skin, indicating greater vessel transcapillary diffusion.
(13) The clinical grading system showed that marked or moderate delayed local reactions developed in one third of patients with atopic dermatitis in response to HDM application to both mildly eczematous and clinically uninvolved skin.
(14) Ig in skin biopsies from uninvolved flexor forearm skin to an objective measure of disease severity in SLE, i.e., serum antibodies to double stranded DNA (anti-dsDNA) as determined by the Crithidia luciliae indirect immunofluorescence assay.
(15) Approximately 60% of the mice developed typical retinitis characterized by virus-infected cytomegalic cells in the retina and retinal pigment epithelium, focal retinal infiltrates, transition zones between uninvolved and involved retina, and optic neuritis.
(16) Our data revealed that normal, uninvolved and involved human epidermal preparations lack the capacity to desaturate 18:2n6 to 18:3n6 and 20:3n6 to 20:4n6.
(17) One month before the patient's death from disseminated nocardial infection, the previously uninvolved right eye developed a new metastatic nocardial chorioretinal lesion.
(18) The tumour contained a higher proportion of inactive renin than was found in uninvolved areas of the kidney.
(19) Skin biopsies of non-atopic healthy controls or clinically uninvolved skin in mycosis fungoides had neither any IgE+ cells nor any vacant binding sites.
(20) In this paper, an uninvolved preparation technique is described for routine testing.