(a.) Separated; having an intervening space; at a distance; away.
(a.) Far separated; far off; not near; remote; -- in place, time, consanguinity, or connection; as, distant times; distant relatives.
(a.) Reserved or repelling in manners; cold; not cordial; somewhat haughty; as, a distant manner.
(a.) Indistinct; faint; obscure, as from distance.
(a.) Not conformable; discrepant; repugnant; as, a practice so widely distant from Christianity.
Example Sentences:
(1) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(2) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The stage of a given malignancy, representing the degree of spread of the tumor to its local surroundings or distant sites, is the best predictor of long-term survival.
(5) Seven patients died, six because of distant metastases within one year.
(6) Local or distant metastases presented in 6 patients.
(7) His office - with a floor-to-ceiling glass wall offering views over a Bradford suburb and distant moors - is devoid of knick-knacks or memorabilia.
(8) Generally, more distant neurones (500-1300 microns) were excited for variable periods of time (3-15 min), while neurones in the vicinity of the injection site (0-500 microns) showed, after a brief period of excitation time, a long-lasting (up to 30 min) decrease in excitability or silencing of discharge, probably due to a depolarizing block and disturbances in the ionic composition of the extracellular space.
(9) Using the Italian I distantly remember from my year abroad in Florence as a student (mi chiama Hadley!
(10) The national study accrued 216 patients with measurable or evaluable non-small cell lung cancer (NSCLC) with either unresectable stage III, or distant metastasis (stage IV).
(11) The special advantage of the UV-beam is that it allow to inactivate selectively of the particular elements of nuclear apparatus of living ciliates is to observe consequences of operation on distant descendants of irradiated cell.
(12) Although a high rate of local control can be expected, distant metastases continue to be a problem.
(13) Indeed, the geographical nature of the division also keeps a check on the club's carbon footprint – Dartford rarely have to travel far outside the M25, with the trips to Bognor Regis and Margate about as distant as they get.
(14) Concomitant immunity (CI) is defined as the lack or retardation or proliferation of a secondary tumor implant at a distant site; it has been given an immunological interpretation.
(15) Children with osteosarcoma or Ewing's sarcoma rarely have bone disease distant from the site of their primary bone lesion at presentation.
(16) The effect of combined treatment was studied in 97 patients with nonseminomatous testicular tumors with regional and distant metastases with regard to the blood serum levels of alpha-fetoprotein and chorionic gonadotropin.
(17) At diagnosis, 15 (16.5%) patients had regional metastases and six (7%) had distant metastases.
(18) The PPi-dependent Pfk of potato is only distantly related to the ATP-dependent enzymes.
(19) Sequences homologous to Inp are present in multiple copies in the N. plumbaginifolia and the N. tabacum genome but not in more distant species.
(20) Local or regional recurrence without evidence of distant metastases was identified in 11 per cent of cases after 'curative' resections.
Utmost
Definition:
(a.) Situated at the farthest point or extremity; farthest out; most distant; extreme; as, the utmost limits of the land; the utmost extent of human knowledge.
(a.) Being in the greatest or highest degree, quantity, number, or the like; greatest; as, the utmost assiduity; the utmost harmony; the utmost misery or happiness.
(n.) The most that can be; the farthest limit; the greatest power, degree, or effort; as, he has done his utmost; try your utmost.
Example Sentences:
(1) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(2) In order to achieve guineaworm eradication in 1990s, the Guineaworm Eradication Programme (GWEP) should operate with utmost efficiency; and needs to be concurrently evaluated for timely corrective measures.
(3) The pH of the extraction buffer was of the utmost importance, since it was demonstrated that a pH greater than 5 would give rise to false signals.
(4) Whereas live Toxoplasma "vaccines" may be effective in sheep and goats, the eventual preparation of a killed vaccine capable of inducing long-term protection is of the utmost importance.
(5) Despite advantages and technological advances in the techniques of dental casts and ceramics attachment to metal, plastic materials for crown and bridge facetting are still of utmost importance for prosthetic procedures.
(6) * * * Stalker, meanwhile, having made his decision, pursued Tape 042 with the utmost vigour.
(7) Early recognition of the major peroxisomal disorders in which functional peroxisomes are virtually absent, leading to a generalised impairment of peroxisomal functions, is of utmost importance, as this will enable the prenatal diagnosis of these severe diseases in future pregnancies.
(8) It is incumbent on the US, Britain and France to do their utmost to help the country win the peace.
(9) We conclude that the stimulation of Pk-C is of utmost importance for OL regeneration.
(10) However, it is of utmost importance that the institutes in "Eastern Europe" establish these standards as soon as possible in order to be competitive and to be able to join research-projects with "Western" universities - a necessary source of income.
(11) A consultant knowledgeable in the problems of the spinal cord injured can be of utmost benefit especially in the labor and delivery process.
(12) Intubation, artificial ventilation, fluid administration (electrolyte-solution) are of utmost importance for their survival and to reduce the frequency of major complications.
(13) As such, we treat any such allegations with the utmost seriousness and we will be contacting Jess to offer to discuss her concerns in full.” Sutton, in his own statement, said: “I wholeheartedly deny that I said or did anything other than act with complete professionalism in my dealings with Jess.
(14) Incidence of renal hydatid cyst is rare and its diagnosis should be made with the utmost care and after subjecting the patient to intensive investigations to exclude other pathologies.
(15) Both numbering systems initiate at the utmost 5' terminus of mRNA synthesis; this 5' initiator nucleotide is assigned 1.
(16) He fulfilled a difficult role in a progressive and compassionate way … he has done his utmost to transform the CPS's record on rape and domestic violence, delivering improved conviction rates for both.
(17) This is of the utmost importance, both epidemiologically and from the individual patient's point of view, and is a prerequisite in preventing the spread of HIV infection.
(18) This may be partly due to excessive patient fear according to the general belief that the heart is the utmost important part of life.
(19) Vaginal scanning of the ovaries and the uterus is a diagnostic and monitoring tool of utmost importance in assisted conception.
(20) In severe cases where hemorrhages play so large a role, albeit infrequently, the specific action of iron in interference with coagulation mechanisms is of the utmost importance.