(v. t.) To temper or mix unduly; to make disproportionate; to change the due proportions of.
(v. t.) To derange the functions of, whether bodily, mental, or spiritual; to disorder; to disease.
(v. t.) To deprive of temper or moderation; to disturb; to ruffle; to make disaffected, ill-humored, or malignant.
(v. t.) To intoxicate.
(v. t.) To mix (colors) in the way of distemper; as, to distemper colors with size.
(v. t.) An undue or unnatural temper, or disproportionate mixture of parts.
(v. t.) Severity of climate; extreme weather, whether hot or cold.
(v. t.) A morbid state of the animal system; indisposition; malady; disorder; -- at present chiefly applied to diseases of brutes; as, a distemper in dogs; the horse distemper; the horn distemper in cattle.
(v. t.) Morbid temper of the mind; undue predominance of a passion or appetite; mental derangement; bad temper; ill humor.
(v. t.) Political disorder; tumult.
(v. t.) A preparation of opaque or body colors, in which the pigments are tempered or diluted with weak glue or size (cf. Tempera) instead of oil, usually for scene painting, or for walls and ceilings of rooms.
(v. t.) A painting done with this preparation.
Example Sentences:
(1) The ultrastructural features of demyelination in viral leukoencephalomyelitis of goats were compared with those described for demyelination that occurs in multiple sclerosis, experimental allergic encephalomyelitis, canine distemper encephalomyelitis, and that produced by diphtheria toxin.
(2) Four, 57 days old, African hunting dog puppies (Lycaon pictus) from one litter died within three weeks following vaccination with modified-live canine distemper virus (CDV) and killed canine adenovirus type 1, canine parvovirus and Leptospira icterohemorrhagiae and canicola.
(3) Particular attention is paid to the aetiology, pathogenesis and epizootiology as well as the prevention of distemper by vaccination.
(4) On inoculation of dogs, a species restricted for avipoxvirus replication, the recombinants elicited a protective immune response against a lethal canine distemper virus (CDV) challenge.
(5) The morphology and cellular localization of the structures resembled those seen in systemic lupus erythematosus in man, and in cultures of cells from tissue infected with canine distemper.
(6) A third group of dogs, characterized by chronic persistent infection, had intermediate levels of anitbody to canine distemper virus.
(7) Distemper-infected dogs with inherited C3 deficiency exhibited enhanced renal glomerular disease associated chiefly with deposition of IgM in mesengial regions vs. their homozygous normal CDV-infected littermates.
(8) Nucleocapsid (NC) variants expressed by the Onderstepoort strain of canine distemper virus (CDV) were ultrastructurally and biochemically characterized.
(9) Canine distemper virus was isolated from four animals and paramyxovirus nucleocapsids were observed by electron microscopy of feces from all affected black-footed ferrets.
(10) The conditions mentioned are: ticks, and tickborne diseases, rabies, distemper, feline panleukopenia, trypanosomiasis, hookworm and tumbu-fly infections.
(11) Canine distemper virus-immune complex-induced oligodendroglial pathology is thought to be mediated by toxic factors released from stimulated macrophages, this bystander effect demonstrated here in vitro may be relevant to the mechanisms of demyelination in vivo, in which virus persistence plays an important role.
(12) Evidence was obtained that the pathogenesis of experimental PDV-infection in harbour seals shares some features with those of canine distemper in terrestrial carnivores.
(13) Canine distemper virus was labelled with tritiated uridine and, following precipitation with saturated ammonium sulphate solution, was concentrated 66-fold by centrifugation through a discontinuous sucrose gradient.
(14) Messenger RNAs from Vero cells infected with the Onderstepoort strain of canine distemper virus (CDV) were cloned into the PstI site of plasmid pAT153.
(15) Weddell seals in the Antarctica had high neutralizing antibody titres to seal- and feline herpesvirus and none against phocine distemper virus.
(16) Changes in abundance at haul-out sites were followed, and data on the number of deaths collected, to describe the pattern and extent of mortality resulting from the 1988 phocine distemper virus outbreak in the Moray Firth common seal population.
(17) However, analogy with canine distemper virus (CDV) suggests that translation of the F protein starts at the sixth AUG codon in the mRNA sequence which is located at position 461, resulting in an F0 protein of exactly the same size (537 aa) as that of CDV.
(18) The presenting signs are described and the aetiology due to canine distemper, trauma and hypothyroidism mentioned.
(19) This effect does not appear to be as severe as that observed for feline leukemia virus of kittens nor as for canine distemper virus in dogs.
(20) Furthermore, a conserved region with about 100 amino acids was observed between PIV-4s and other paramyxoviruses, Newcastle disease virus (NDV), Sendai virus, mumps virus (MuV), PIV-3, BPIV-3, measles virus (MV), and canine distemper virus (CDV), indicating a common ancestor for these nine viruses.
Malady
Definition:
(n.) Any disease of the human body; a distemper, disorder, or indisposition, proceeding from impaired, defective, or morbid organic functions; especially, a lingering or deep-seated disorder.
(n.) A moral or mental defect or disorder.
Example Sentences:
(1) It shares some characteristics with the maladie dermatophytique of Hadida and Schousboe.
(2) This treatment was given to 11 patients with Huntington's chorea (ChH), 4 with faciolingual dyskinesis (DFL), 3 with torticollis spasmodicus (TS), 3 with maladie des tics (MT) and 8 with dyskinesia following treatment with L-dopa (MP).
(3) The cries were the pain cries of 2 normal newborns, 1 infant with maladie du cri du chat, 1 with Down syndrome, 1 asphyxiated infant with brain damage, and one asphyxiated infant without brain damage.
(4) We are not claiming that this procedure is a cure for CHD; rather, it is a procedure that dramatically slows down the progress of this malady and allows the dog to lead a more normal lifestyle and avoids euthanasia.
(5) These and other maladies and temptations are a danger for every Christian and for any administrative organisation … and can strike at both the individual and the corporate level,” he said.
(6) It is a microcosm of the region’s maladies and the trauma they have wrought on civilian lives – there are people here who have been wounded in sectarian bloodletting, shelling, airstrikes, occupation and crackdowns by dictators.
(7) Acalculous cholecystitis is an unusual but serious variant of a common disorder in which treatable gallbladder disease may masquerade as a less treatable liver malady.
(8) Although high resolution CT is preferable for study of common maladies of the middle ear and optic capsule, MRI is currently the study of choice for evaluation of the internal auditory canal, cerebellopontine angle, and brainstem.
(9) 93% of the subjects suffered from diabetes mellitus as the basal malady, which was comparable to that in Western studies.
(10) In children with known associated severe medical maladies, diagnostic barium enema can serve to reaffirm the diagnosis prior to the hazardous operative intervention.
(11) No mention of how losing weight (and avoiding maladies) through such surgery could save the NHS millions and therefore be classed as relatively cost-effective.
(12) When humans encounter marine creatures a variety of maladies may occur, ranging from dermatitis to life-threatening trauma, allergy, envenomations, or intoxications.
(13) A very high percentage of farm flock poultry maladies can be diagnosed by gross lesions plus a few simple laboratory procedures, such as direct microscopy, Gram's stain, fecal flotation, and aerobic bacteriology.
(14) Nostalgia was the soldiers’ malady – a state of mind that made life in the here and now a debilitating process of yearning for that which had been lost: rose-tinted peace, happiness, loved ones.
(15) Using a double-blind crossover technique in patients suffering from maladies associated with gastrointestinal spasm, sustained-release 40 mg dicyclomine hydrochloride tablets (Merbentyl Dospan) have been compared with 20 mg plain dicyclomine hydrochloride tablets (Merbentyl).
(16) In the majority of cases the grafts were penetrating (105 out of 118 cases), and the overall analysis of the results is dependent on the following factors: -- Grafts performed as primary procedures in one eye or both eyes: if they develop maladie due greffon, it is usually the 'endothelial' form which appears between the first and third month; the prognosis is good (53-66 p. 100 cure with steroid therapy).
(17) This malady accounts for 20 to 30 per cent of all congenital cardiac defects and is representative of a cardiac lesion that increases pulmonary blood flow.
(18) Spirochetes were not isolated in Danbury or New Hartford, areas where this malady is rare.
(19) Nowhere are the symptoms of this malady more visible than in medicine.
(20) » Une résidente du village, Bella Kabatesi, 18 ans, dont les parents sont morts suite à une maladie lorsqu’elle avait quatre ans, a utilisé l’énergie solaire pour alimenter une veilleuse en mémoire du fondateur du village, désormais décédé.