(v. t.) To cease to use; to discontinue the practice of.
(v. t.) To disaccustom; -- with to or from; as, disused to toil.
(n.) Cessation of use, practice, or exercise; inusitation; desuetude; as, the limbs lose their strength by disuse.
Example Sentences:
(1) He gets Lyme disease , he dates indie girls and strippers; he lives in disused warehouses and crappy flats with weirded-out flatmates who want to set him on fire and buy the petrol to do so.
(2) Roger Madelin, the chief executive of the developers Argent, which consulted the prince's aides on the £2bn plan to regenerate 27 hectares (67 acres) of disused rail land at Kings Cross in London, said the prince now has a similar stature as a consultee as statutory bodies including English Heritage, the Commission for Architecture and the Built Environment and professional bodies including Riba and the Royal Institute of Chartered Surveyors.
(3) Others seek shelter wherever they can – on rented farmland, and in empty houses and disused garages.
(4) Hope was living in a disused council building in Tower Hamlets, east London, and, by maintaining a physical presence on site, providing services for a property guardian company called Newbould Guardians.
(5) To reduce the risks posed by the hazard, the report recommends that a management plan be created to determine the level of soil contamination and for managing excavated soil, and to decommission disused septic tanks to prevent the spread of contamination.
(6) Bone plates allow early weight-bearing, but substitute the problem of stress protection for disuse atrophy.
(7) In this study, we test the hypothesis that monosynaptic connections between la afferents and spinal motoneurons are strengthened by chronic disuse.
(8) In net-curtained rooms above a disused kebab shop on Cricklewood Broadway, a small group of middle-aged men were at work as usual when they found themselves at the centre of a national terror warning.
(9) Two weeks of disuse resulted in 40% muscle weight loss.
(10) In this study, by use of technique that was modified from Morey method, we discussed the histological influence on the soleus muscle of the rats caused by disuse.
(11) A scramble is on to find suitable empty properties, from rooms in private homes, to sports halls and disused school buildings to derelict soldiers’ barracks, even inflatable circus tents.
(12) With the advent of binding assays for vitamin B12 in blood, the Schilling test, which involves administration of radioactive B12 to a patient and subsequent urine collection for 24 to 48 h, fell into disuse in many laboratories.
(13) The results were analyzed with references to the different muscle functions in disuse atrophy.
(14) However, at this time, rates of protein synthesis (measured in vitro) and nucleic acid concentrations were also higher in the denervated tissue, changes more usually associated with an active muscle rather than a disused one.
(15) Chronic muscle disuse decreases the sensitivity of skeletal muscle to nondepolarizing relaxants, such as metocurine (MTC).
(16) This concept has been substantiated by the study of standard fatigue tests performed in control, trained, and disused human muscles, as reviewed in this paper.
(17) Disuse was caused by diverting the flow of urine from the lower urinary tract.
(18) A female juvenile rhesus monkey experienced a 3-wk period of vague lameness and limb disuse, followed by a severe attack of acute polyarthritis resulting in marked radiographic changes.
(19) Before effective countermeasures can be devised, a thorough knowledge of the extent, location, and rate of bone loss during weightlessness is needed from actual space flight data or ground-based disuse models.
(20) In animals, nigrostriatal neurons respond to the blockade of DA synapses by treatment with antipsychotic agents in several ways, including acute and transient increases in the turnover of DA, and more slowly evolving "disuse" supersensitivity, possibly of postsynaptic receptors.
Use
Definition:
(v. t.) The act of employing anything, or of applying it to one's service; the state of being so employed or applied; application; employment; conversion to some purpose; as, the use of a pen in writing; his machines are in general use.
(v. t.) Occasion or need to employ; necessity; as, to have no further use for a book.
(v. t.) Yielding of service; advantage derived; capability of being used; usefulness; utility.
(v. t.) Continued or repeated practice; customary employment; usage; custom; manner; habit.
(v. t.) Common occurrence; ordinary experience.
(v. t.) The special form of ritual adopted for use in any diocese; as, the Sarum, or Canterbury, use; the Hereford use; the York use; the Roman use; etc.
(v. t.) The premium paid for the possession and employment of borrowed money; interest; usury.
(v. t.) The benefit or profit of lands and tenements. Use imports a trust and confidence reposed in a man for the holding of lands. He to whose use or benefit the trust is intended shall enjoy the profits. An estate is granted and limited to A for the use of B.
(v. t.) A stab of iron welded to the side of a forging, as a shaft, near the end, and afterward drawn down, by hammering, so as to lengthen the forging.
(v. t.) To make use of; to convert to one's service; to avail one's self of; to employ; to put a purpose; as, to use a plow; to use a chair; to use time; to use flour for food; to use water for irrigation.
(v. t.) To behave toward; to act with regard to; to treat; as, to use a beast cruelly.
(v. t.) To practice customarily; to make a practice of; as, to use diligence in business.
(v. t.) To accustom; to habituate; to render familiar by practice; to inure; -- employed chiefly in the passive participle; as, men used to cold and hunger; soldiers used to hardships and danger.
(v. i.) To be wont or accustomed; to be in the habit or practice; as, he used to ride daily; -- now disused in the present tense, perhaps because of the similarity in sound, between "use to," and "used to."
(v. i.) To be accustomed to go; to frequent; to inhabit; to dwell; -- sometimes followed by of.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.