(a.) Having two units of combining power; bivalent. Cf. Valence.
Example Sentences:
(1) Binding is inhibited by divalent and trivalent cations (Cd2+ and La3+ being most potent) and other calcium channel drugs (1,4 dihydropyridines, phenylalkylamines, benzothiazepines).
(2) Although GTP most potently inhibited [125I]beta h-endorphin binding in the presence of sodium, inhibition of [125I]beta h-endorphin binding by GTP was also observed in the presence of the monovalent cations lithium and potassium, but not the divalent cations magnesium, calcium, or manganese.
(3) When the concentration of Ca2+ in the medium was raised to 10 mM was the only extracellular divalent cation present, the depolarization in response to A23187 was increased to 11-8 mV.
(4) Protons and divalent cations show synergistic effects on the destabilization of liposomes composed of unsaturated phosphatidylethanolamine and oleic acid (Düzgünes et al., Biochemistry (1985) 24, 3091).
(5) The enzyme is active over a wide range of pH, does not require divalent cations, and is inhibited by sulfhydryl-reactive agents.
(6) In order to determine the specific action of cadmium on bone metabolism, the effect of cadmium on alkaline phosphatase activity, a marker enzyme of osteoblasts, was compared with that of other divalent heavy metal ions, i.e., zinc, manganese, lead, copper, nickel and mercury (10 microM each), using cloned osteoblast-like cells, MC3T3-E1.
(7) The sensitivity to ionic strength, divalent metal ions and polylysine of release of fluorescent markers from liposomes and of haemoglobin from intact erythrocytes has been assayed.
(8) The enzyme is quite thermoresistant in the presence of other proteins, has an optimal temperature of 60 degrees, needs monovalent cations for optimal activity, is insensitive to EDTA, and is inhibited by divalent cations; it has no associated exonuclease activity.
(9) preference of template primer and divalent metal ion, RNA- or DNA-dependent DNA polymerase activity, RNase H activity, and the processive mode of DNA synthesis.
(10) It can be dissociated from the spores using divalent metal chelators and will reassemble on the spores in the presence of calcium.
(11) The presence of Ca2+ in silica gel is responsible for this improved yield of prostaglandin as the divalent metal ion stabilized prostaglandin synthetase activity in a remarkable way.
(12) In view of the above findings, it was hypothesized that polyamines in general took the place of divalent cations in causing membrane stabilization.
(13) The effects of monovalent and divalent cations on the hemolytic activity of Cerebratulus lacteus toxin A-III were studied.
(14) Other divalent metal ions displace Mn2+ from the high affinity sites in the following order of effectiveness: Ca greater than Mg = Zn = Co greater than Sr greater than Ni.
(15) Parameters observed were divalent association rate constants, affinity and autoradiography of isoelectric focusing (IEF) spectra.
(16) At low concentrations, the current-voltage relations are inwardly rectifying, but they become more ohmic if a small amount of divalent cations is added externally.
(17) Divalent cations (2 mM-Ni2+, 1 mM-Ba2+ or 2 mM-Ca2+) reduced only the outward current in the Tris Na(+)-free solution, while in the 150 mM-Na+ solution, they reduced both the inward and outward components of the current which had a reversal potential of around -10 mV.
(18) Cs (IC50 = 5-6 mM) prevented toxin binding, as did the divalent cations Ba and Ca (IC50 = 4-6 and 9-13 mM, respectively).
(19) Similar results were obtained in studies with the intact divalent radiolabelled Leu3a antibody.
(20) After renaturation of polypeptides, the gel was incubated with [gamma-32P]ATP and divalent cations.
Ethylene
Definition:
(n.) A colorless, gaseous hydrocarbon, C2H4, forming an important ingredient of illuminating gas, and also obtained by the action of concentrated sulphuric acid in alcohol. It is an unsaturated compound and combines directly with chlorine and bromine to form oily liquids (Dutch liquid), -- hence called olefiant gas. Called also ethene, elayl, and formerly, bicarbureted hydrogen.
Example Sentences:
(1) 3,4-Dihydroxyphenyl ethylene glycol (DOPEG), a metabolite of noradrenaline (NA), was estimated in CSF of 30 patients of depression diagnosed by the criteria of American Psychiatric Association in DSM-III; and compared with levels in 10 non-depressed individuals who served as controls.
(2) Depletion of extracellular Ca2+ by EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N'N'-tetraacetic acid] attenuated both [Ca2+]i increase and superoxide production induced by particles.
(3) Orotic acid inhibited, dose-dependently DNA synthesis in hepatocytes induced by epidermal growth factor, transforming growth factor alpha, hepatocyte growth factor, acidic fibroblast growth factor, or plasma from rats exposed to various liver cell-proliferative stimuli, such as two-thirds partial hepatectomy, lead nitrate, cyproterone acetate, ethylene dibromide, or a diet deficient in choline.
(4) 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3- nitrosourea hydrochloride (ACNU) causes chloroethylation of DNA strand followed by cross linking through an ethylene bridge.
(5) Chlorinated ethylenes are metabolized in mammals, as a first step, to epoxides.
(6) Therefore, an experimental study was undertaken to assess the suitability of an expanded PTFE (Polytetrafluoro-ethylene) as a microvascular graft.
(7) Solid-phase adsorbents were compared in their trapping efficiencies for dichloromethane (DCM), ethylene dibromide (EDB), 4-nitroblphenyl (4-NB), 2-nitrofluorene (2-NF), and fluoranthene (FI).
(8) Therapeutic application of drugs containing propylene glycol 1.2 as a solvent may distort the results of forensic chemical detection of ethylene glycol from its oxidation products.
(9) It was found that the stress at a given strain was increased by treatment with ethylene oxide, buffered formalin, and tissue culture solution and decreased by treatment with antibiotics.
(10) Practical examples illustrate the possibility of ethylene glycol determination by gas chromatography in the presence of propylene glycol.
(11) Enzymes that pelleted more in myogen preparations than as individual purified enzymes in the presence of poly(ethylene glycol) and the absence of F-actin were tested for specific enzyme-enzyme associations, several of which were observed.
(12) Subacute (10-day) and subchronic (90-day) toxicity studies of ethylene glycol (EG) were conducted in male and female Sprague-Dawley rats to provide the U.S. Environmental Protection Agency's (EPA) Office of Drinking Water with toxicity data for final preparation of a Health Advisory for the chemical.
(13) Two-phase systems consisting of water, dextran and poly(ethylene glycol) have been used for partition of membranes obtained from Torpedo marmorata electric organ.
(14) Rats have been exposed in a closed system to the chlorinated ethylenes vinyl chloride and trichloroethylene and to carbon tetrachloride as a reference compound.
(15) For two chemicals, dichlorobenzidine and ethylene thiourea, there is not enough epidemiological information to make a useful comparison with rodent bioassay data.
(16) We examined the effect of ethylene glycol (EG) concentration, in water, on O2 sensitivity, stirring effect, in vitro drift, in vitro response time, behaviour on the skin of newborn infants and in vivo response time.
(17) As a prerequisite for preparing bispecific antibody conjugates containing anti-tumor and anti-metal chelate binding sites that can be used for pretargeted immunoscintigraphy, monoclonal antibodies (Mabs) have been raised against an octahedral metal chelate synthetized from gallium (Ga) and the hexadentate ligand N,N'bis[2-hydroxy 5-(ethylene beta carboxy) benzyl] ethylenediamine N,N' diacetic acid (Ga-HBED-CC).
(18) In heavily mineralized bone matrix, the periodic pattern of collagen fibrils was retained, and the electron density of mineralized matrix in freeze-substituted and unstained sections which had been floated on ethylene glycol was greater than that encountered in sections processed in aqueous reagents.
(19) Paraquat (1,1'-dimethyl-4,4'-bipyridylium) and diquat (1,1'-ethylene-2,2'-bipyridylium) are the two most widely used bipyridylium herbicides today.
(20) Moreover, in patients dialysed using ethylene oxide sterilized equipment, anaphylactoidal reactions were observed.