(a.) Having two units of combining power; bivalent. Cf. Valence.
Example Sentences:
(1) Binding is inhibited by divalent and trivalent cations (Cd2+ and La3+ being most potent) and other calcium channel drugs (1,4 dihydropyridines, phenylalkylamines, benzothiazepines).
(2) Although GTP most potently inhibited [125I]beta h-endorphin binding in the presence of sodium, inhibition of [125I]beta h-endorphin binding by GTP was also observed in the presence of the monovalent cations lithium and potassium, but not the divalent cations magnesium, calcium, or manganese.
(3) When the concentration of Ca2+ in the medium was raised to 10 mM was the only extracellular divalent cation present, the depolarization in response to A23187 was increased to 11-8 mV.
(4) Protons and divalent cations show synergistic effects on the destabilization of liposomes composed of unsaturated phosphatidylethanolamine and oleic acid (Düzgünes et al., Biochemistry (1985) 24, 3091).
(5) The enzyme is active over a wide range of pH, does not require divalent cations, and is inhibited by sulfhydryl-reactive agents.
(6) In order to determine the specific action of cadmium on bone metabolism, the effect of cadmium on alkaline phosphatase activity, a marker enzyme of osteoblasts, was compared with that of other divalent heavy metal ions, i.e., zinc, manganese, lead, copper, nickel and mercury (10 microM each), using cloned osteoblast-like cells, MC3T3-E1.
(7) The sensitivity to ionic strength, divalent metal ions and polylysine of release of fluorescent markers from liposomes and of haemoglobin from intact erythrocytes has been assayed.
(8) The enzyme is quite thermoresistant in the presence of other proteins, has an optimal temperature of 60 degrees, needs monovalent cations for optimal activity, is insensitive to EDTA, and is inhibited by divalent cations; it has no associated exonuclease activity.
(9) preference of template primer and divalent metal ion, RNA- or DNA-dependent DNA polymerase activity, RNase H activity, and the processive mode of DNA synthesis.
(10) It can be dissociated from the spores using divalent metal chelators and will reassemble on the spores in the presence of calcium.
(11) The presence of Ca2+ in silica gel is responsible for this improved yield of prostaglandin as the divalent metal ion stabilized prostaglandin synthetase activity in a remarkable way.
(12) In view of the above findings, it was hypothesized that polyamines in general took the place of divalent cations in causing membrane stabilization.
(13) The effects of monovalent and divalent cations on the hemolytic activity of Cerebratulus lacteus toxin A-III were studied.
(14) Other divalent metal ions displace Mn2+ from the high affinity sites in the following order of effectiveness: Ca greater than Mg = Zn = Co greater than Sr greater than Ni.
(15) Parameters observed were divalent association rate constants, affinity and autoradiography of isoelectric focusing (IEF) spectra.
(16) At low concentrations, the current-voltage relations are inwardly rectifying, but they become more ohmic if a small amount of divalent cations is added externally.
(17) Divalent cations (2 mM-Ni2+, 1 mM-Ba2+ or 2 mM-Ca2+) reduced only the outward current in the Tris Na(+)-free solution, while in the 150 mM-Na+ solution, they reduced both the inward and outward components of the current which had a reversal potential of around -10 mV.
(18) Cs (IC50 = 5-6 mM) prevented toxin binding, as did the divalent cations Ba and Ca (IC50 = 4-6 and 9-13 mM, respectively).
(19) Similar results were obtained in studies with the intact divalent radiolabelled Leu3a antibody.
(20) After renaturation of polypeptides, the gel was incubated with [gamma-32P]ATP and divalent cations.
Two
Definition:
(n.) One and one; twice one.
(n.) The sum of one and one; the number next greater than one, and next less than three; two units or objects.
(n.) A symbol representing two units, as 2, II., or ii.
Example Sentences:
(1) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
(2) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) Two of the largest markets are Germany and South Korea, often held up as shining examples of export-led economies.
(5) Although the mean values for all hemodynamic variables between the two placebo periods were minimally changed, the differences in individual patients were striking.
(6) The authors have presented in two previous articles the graphic solutions resembling Tscherning ellipses, for spherical as well as for aspherical ophthalmic lenses free of astigmatism or power error.
(7) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
(8) After two weeks all animals were killed and autopsies of the animals were performed.
(9) No differences between the two substances were observed with respect to side effects and general tolerability.
(10) Anti-corruption campaigners have already trooped past the €18.9m mansion on Rue de La Baume, bought in 2007 in the name of two Bongo children, then 13 and 16, and other relatives, in what some call Paris's "ill-gotten gains" walking tour.
(11) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(12) Between 22 HLA-identical siblings and 16 two-haplotype different siblings, a significant difference in concordance of reactions for the B-cell groups was noted.
(13) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(14) The constitution of chromosomes in the two plasmacytomas remained remarkably stable in their homogeneous modal population.
(15) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(16) At pH 7.0, reduction is complete after 6 to 10 h. These results together with an earlier study concerning the positions of the two most readily reduced bonds (Cornell J.S., and Pierce, J.G.
(17) Gel filtration of the 40,000 rpm supernatant fraction of a homogenate of rat cerebral cortex on a Sepharose 6B column yielded two fractions: fraction II with the "Ca(2+) plus Mg(2+)-dependent" phosphodiesterase activity and fraction III containing its modulator.
(18) A diplomatic source said the killing appeared particularly unusual because of Farooq lack of recent political activity: "He was lying low in the past two years.
(19) However, as the same task confronts the Lib Dems, do we not now have a priceless opportunity to bring the two parties together to undertake a fundamental rethink of the way social democratic principles and policies can be made relevant to modern society.
(20) The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes.