(a.) Having two units of combining power; bivalent. Cf. Valence.
Example Sentences:
(1) Binding is inhibited by divalent and trivalent cations (Cd2+ and La3+ being most potent) and other calcium channel drugs (1,4 dihydropyridines, phenylalkylamines, benzothiazepines).
(2) Although GTP most potently inhibited [125I]beta h-endorphin binding in the presence of sodium, inhibition of [125I]beta h-endorphin binding by GTP was also observed in the presence of the monovalent cations lithium and potassium, but not the divalent cations magnesium, calcium, or manganese.
(3) When the concentration of Ca2+ in the medium was raised to 10 mM was the only extracellular divalent cation present, the depolarization in response to A23187 was increased to 11-8 mV.
(4) Protons and divalent cations show synergistic effects on the destabilization of liposomes composed of unsaturated phosphatidylethanolamine and oleic acid (Düzgünes et al., Biochemistry (1985) 24, 3091).
(5) The enzyme is active over a wide range of pH, does not require divalent cations, and is inhibited by sulfhydryl-reactive agents.
(6) In order to determine the specific action of cadmium on bone metabolism, the effect of cadmium on alkaline phosphatase activity, a marker enzyme of osteoblasts, was compared with that of other divalent heavy metal ions, i.e., zinc, manganese, lead, copper, nickel and mercury (10 microM each), using cloned osteoblast-like cells, MC3T3-E1.
(7) The sensitivity to ionic strength, divalent metal ions and polylysine of release of fluorescent markers from liposomes and of haemoglobin from intact erythrocytes has been assayed.
(8) The enzyme is quite thermoresistant in the presence of other proteins, has an optimal temperature of 60 degrees, needs monovalent cations for optimal activity, is insensitive to EDTA, and is inhibited by divalent cations; it has no associated exonuclease activity.
(9) preference of template primer and divalent metal ion, RNA- or DNA-dependent DNA polymerase activity, RNase H activity, and the processive mode of DNA synthesis.
(10) It can be dissociated from the spores using divalent metal chelators and will reassemble on the spores in the presence of calcium.
(11) The presence of Ca2+ in silica gel is responsible for this improved yield of prostaglandin as the divalent metal ion stabilized prostaglandin synthetase activity in a remarkable way.
(12) In view of the above findings, it was hypothesized that polyamines in general took the place of divalent cations in causing membrane stabilization.
(13) The effects of monovalent and divalent cations on the hemolytic activity of Cerebratulus lacteus toxin A-III were studied.
(14) Other divalent metal ions displace Mn2+ from the high affinity sites in the following order of effectiveness: Ca greater than Mg = Zn = Co greater than Sr greater than Ni.
(15) Parameters observed were divalent association rate constants, affinity and autoradiography of isoelectric focusing (IEF) spectra.
(16) At low concentrations, the current-voltage relations are inwardly rectifying, but they become more ohmic if a small amount of divalent cations is added externally.
(17) Divalent cations (2 mM-Ni2+, 1 mM-Ba2+ or 2 mM-Ca2+) reduced only the outward current in the Tris Na(+)-free solution, while in the 150 mM-Na+ solution, they reduced both the inward and outward components of the current which had a reversal potential of around -10 mV.
(18) Cs (IC50 = 5-6 mM) prevented toxin binding, as did the divalent cations Ba and Ca (IC50 = 4-6 and 9-13 mM, respectively).
(19) Similar results were obtained in studies with the intact divalent radiolabelled Leu3a antibody.
(20) After renaturation of polypeptides, the gel was incubated with [gamma-32P]ATP and divalent cations.
Valence
Definition:
(n.) The degree of combining power of an atom (or radical) as shown by the number of atoms of hydrogen (or of other monads, as chlorine, sodium, etc.) with which it will combine, or for which it can be substituted, or with which it can be compared; thus, an atom of hydrogen is a monad, and has a valence of one; the atoms of oxygen, nitrogen, and carbon are respectively dyads, triads, and tetrads, and have a valence respectively of two, three, and four.
Example Sentences:
(1) The mixed-valence-state cytochrome oxidase mixed with O2 at -24 degrees C and flash-photolysed at -60 to -100 degrees C reacts with O2 and initially forms an oxy compound (A2) similar to that formed from the fully reduced state (A1).
(2) Additional results, together with simulations based on a simple kinetic model, suggest that the reduced apparent valence of the low slope component of the Q-V curve results from gating charge immobilization occurring at holding potential.
(3) A related explanation is that the 609 nm absorbance involves a charge-transfer interaction of both iron and copper as a mixed-valence binuclear complex, Cua3, having properties of a non-blue copper.
(4) RBDs were significantly more impaired than LBDs or NCs on category and valence accuracy, while LBDs posed expressions with significantly more intensity than RBDs or NCs.
(5) The extent of adsorption was affected by the concentration and valency of cations, indicating a charge-dependent process.
(6) Use of that principle was demonstrated by fourth grade children who judged that telling the truth, as opposed to lying, was shown by a consistency between the affective valence of the verbal and the nonverbal communications.
(7) Research reported here shows that primary and transferred releasing valences are differentially affected by environmental variables.
(8) Furthermore, the valences of all ions in solution on both sides of the membrane are taken to be of equal absolute magnitude.
(9) Possible valence bond structures for 3-methylpurine residues in DNA are discussed, leading to the suggestion that ionized forms with positively charged amino groups may be the most effective blocks to template activity.
(10) A confirmatory factor analysis on these subscales showed that the Affective Valence, Empathic Caring, Self-Sacrifice, and Societies' Duties subscales each reflect a humanitarian concern for children and that the Instrumentality and Authoritarian Attitude subscales tap values involving a moralistic expectation of children.
(11) The excitatory potential, the involvement potential, and the hedonic valence of the nonerotic and erotic stimuli were also assessed.
(12) A monovalent form of concanavalin A (m-Con A) has been prepared to determine the importance of valence for human lymphocyte surface binding and subsequent lymphocyte stimulation as measured by blast transformation and cytotoxicity.
(13) As concerns the valence of the natural focus, the most important was the inundated forest in the Drnholec locality.
(14) Examination of the antigen dose-response curves and maximal responses obtained suggests that valency of the antigen may be important both in determining the avidity of interaction between the pCTL and the antigen-bearing structure, and in determining the extent to which localized receptor cross-linking occurs on the cell surface to result in triggering.
(15) Therefore, no conclusions about biological valence and tumour localisation could be drawn from the aspect of the cell picture which we observed and from the degree of pleocytosis.
(16) During presentation of pictures with negative valence the m. frontalis lateralis and the m. corrugator supercilii revealed enhanced EMG-reactions as compared to the repeated presentation of pictures with positive valence.
(17) The degree and the character of these changes depend on cation valency and the initial value of cell EM.
(18) Maximum adsorption at 23 degrees C occurred within 2 h. The amounts of DNA which adsorbed to sand increased with the salt concentration (0.1 to 4 M NaCl and 1 mM to 0.2 M MgCl2), salt valency (Na+ less than Mg2+ and Ca2+), and pH (5 to 9).
(19) The influence of valence and heavy chain on antibody activity was investigated using transfectoma-derived, class-switched IgG1 and IgM human monoclonal antibodies (MAbs) reactive with the bacterial pathogens Escherichia coli K1 and group B Streptococcus species.
(20) The obtained data allows to suggest that one of the possible mechanisms of 6-ONDA neurotoxic action includes the generation of superoxide, whose dismutation to hydrogen peroxide in the presence of transient valency ions gives rise to HO.