(n.) The act of making various, or of changing form or quality.
(n.) State of diversity or variation; variegation; modification; change; alternation.
Example Sentences:
(1) Further diversification of the V lambda 1 locus did not occur after prolonged in vitro passage of the cell lines.
(2) The discrepancy between the judgement of the insurance company based upon the medical records and the patients complaints also 4-7 years after injury as well as the diversification of therapeutical procedures used in the long term patients career are indicating a necessity of prospective study on cervical spine injury.
(3) "2013 was a tough year for us both in minerals and in oil and gas," Cochrane said, adding that the group had relied on"self help", including diversification which offset some of the challenges in its core mining market, improving operational efficiency, and strong growth in its after sales business, where orders were up 16% on 2012 and which accounted for 63% of revenues last year.
(4) Diversification within these tumor cells seems to occur by gene conversion events comparable with those observed in bursal B cells.
(5) These results suggest that during tumor development, alterations in the relative levels of S-adenosylhomocysteine and S-adenosylmethionine may lead to the inhibition of DNA methylation, resulting in the activation of previously quiescent genes, thereby promoting the phenotypic diversification of tumor cell populations as well as their progression from a relatively benign to a highly malignant state.
(6) In addition, antibody molecules derived by somatic diversification from the same germ line gene segments could be distinguished from one another.
(7) Thus, cell fates are segregated during cleavage stages in both symmetric and asymmetric manners, and the lineages exhibit a diversification mode (G. S. Stent, 1985, Philos.
(8) The medical treatment has been diversificated according to the cause which has generated it, with normalisation of the ocular pressure and sight ameliorations in 50 p. 100 of cases.
(9) The developmental and phenotypic characteristics of the bursal lymphocytes and chicken B cell lines that express RAG-2 mRNA demonstrate that selective RAG-2 expression occurs specifically in B cells undergoing Ig diversification by gene conversion.
(10) Certain aspects of this regional diversification result from competitive cell interactions which occur at the level of the postmitotic neuron.
(11) We report evidence suggesting that this cellular diversification can be brought about by the combinatorial action of two diffusible signals, cAMP and DIF-1.
(12) The diversification into infrastructure for battery-powered cars would mark a new departure for the company, which has largely backed biofuels as a greener alternative to petrol and diesel in the past.
(13) The onset of D diversification through gene conversion between day 15 and day 18 of embryonic development is further documented.
(14) Light-chain diversification occurs during or after the rearrangement event.
(15) The extraordinary polymorphism of class I MHC molecules in man (HLA-A, B and C) and mouse (H-2 K, D and L) poses many questions concerning their diversification and evolution.
(16) These results throw further light onto the complex processes of fetal development of eccrine sweat glands and their cellular diversification.
(17) The genetic mechanism responsible for the somatic diversification of two mAbs was determined.
(18) "Product and service diversification, infrastructure investment and platforms for direct consumer interaction ... it will be the next CEO's role to continue that transformation.
(19) Williams hopes renewed government interest in the sector, and the diversification of Britain's skills base, will help change the public's perceptions of manufacturing and engineers.
(20) Diversification of a duplicated ancestral sequence has resulted in three lipid-binding proteins with distinct and shared functions.
Variegation
Definition:
(n.) The act of variegating or diversifying, or the state of being diversified, by different colors; diversity of colors.
Example Sentences:
(1) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(2) Such characteristics are reminiscent of the behavior of variegating position-effects in Drosophila and the application of this paradigm to human disease phenotypes provides both a mechanism by which differential genome imprinting may be accomplished as well as genetic models that may explain the clinical association of syntenic diseases, the association between tumor progression and specific chromosomal aneuploidy and the unusual inheritance characteristics of many diseases.
(3) The diagnosis depends on fecal excretion of porphyrins, which is greatly increased in variegate porphyria and consists predominantly of protoporphyrin.
(4) Although clinical improvements occurred in the case of variegate porphyria, the results were inconclusive for reasons given.
(5) Appropriate laboratory tests on urine and feces samples are necessary to distinguish between PCTS and variegate porphyria when a young woman presents with the skin lesions characteristic of cutaneous hepatic porphyrias.
(6) One patient with variegate prophyria and two with hereditary coproporphyria had an attack related to pregnancy.
(7) The theory of the unconscious that arises from the method of direct interpretation reflects a differentiated inner world with variegated landscapes of images and frameworks.
(8) The faecal porphyrin patterns of 24 patients with porphyria cutanea tarda symptomatica (PCTS), eight patients with variegate porphyria, three patients with other types of porphyria, and 20 non-porphyrics subjects have been compared using a two-demensional thin layer chromatographic technique that separates porphyrins of the isocoproporphyrin series from other faecal porphyrins.
(9) A 62-year-old man with variegate porphyria is reported.
(10) Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks.
(11) Hence, the differences in binding of the w+ gene probe in the variegating and variegation-suppressed strains reflect differences in chromosomal packaging rather than alterations in gene number.
(12) The lesions appeared brownish black, and most were variegated from tan to black.
(13) Thus, mice with variegating transgenes can provide molecular access to gene control mechanisms and to their consequences in development and disease.
(14) The results provide some indication as to the mechanism and timing for the general suppression of position-effect variegation by supernumerary heterochromatin in the genome.
(15) Beautiful and ancient plants, such as spreading bellflower , could become extinct in some places through the escape of variegated yellow archangel from gardens.
(16) Variegated endocrine cells were documented within this lining, using immunohistochemical and ultrastructural techniques.
(18) In white-mottled (wm) position-effect variegation mutants, a significant correlation was found between the extent of variegation (percentage of yellow cells) and riboflavin content (growth effect) of the MT.
(19) Four patients suffering from variegate prophyria were investigated during acute attacks.
(20) These changes include variegated hyperplasia of the pulp with epithelioid cells, mature eosinophilic granulocytes and immunoblasts occasionally resembling Hodgkin cells.