(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.
Dom
Definition:
(n.) A title anciently given to the pope, and later to other church dignitaries and some monastic orders. See Don, and Dan.
(n.) In Portugal and Brazil, the title given to a member of the higher classes.
Example Sentences:
(1) Taken together with our previous studies showing that MDMA substitutes for the phenylisopropylamine stimulant (+)amphetamine, but that neither MDE nor N-OH MDA substitute for (+)amphetamine or for the phenylisopropylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), the present results [i.e., MDMA-stimulus generalization to MDE, N-OH MDA, but not to (+)amphetamine] suggest that 1) MDMA produces effects other than those that may be considered amphetamine-like, and 2) MDE and N-OH MDA are MDMA-like agents with even less of an amphetamine-like component of action than MDMA itself.
(2) Farage previously appeared in an alcohol-fuelled Gogglebox special on Channel 4, with “posh couple” Steph and Dom Parker.
(3) But 30 minutes before takeoff on our private jet – like a top-end Lexus limo with wings – actress Rosamund Pike has heroically stepped in for the year's hot meal ticket: an El Bulli supper, pitch perfect for a selection of rare champagne, devised by Adrià with Richard Geoffroy, Dom Pérignon's effervescent chef de cave.
(4) The biggest gain for most non-doms is the allowance for tax-free offshore capital growth.
(5) Long pauses were found with LSD-25, 2,5-dimethoxy-4-methylamphetamine (DOM) and mescaline.
(6) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(7) Non-doms could no longer pretend to live in Monaco while living in the UK for four working days a week.
(8) In a statement published shortly before the disclosure of material as a result of freedom of information requests, Ashcroft indicated he would relinquish his non-dom status in line with new Tory policy to remain in the Lords.
(9) In conclusion, enhanced avoidance of novel and central areas appears to be a valid indicator of hallucinogenic activity since LSD, DMT, and DOM all share this property.
(10) Dom's being very hard on himself - he couldn't write spurious nonsense if he tried.
(11) She has written books on how to be a success and hosts Dom-2 , the longest-running reality show in the world, which has been memorably described as the worst thing to hit Russian culture since the Mongols.
(12) 2,5-Dimethoxy-4-methylamphetamine (DOM, "STP") is a potent hallucinogen, proposed to be a serotonin receptor agonist.
(13) With the Dynamo winning three of their last four, that scenario was becoming more likely, though disciples of the Church of Dom were given reason for pause on Saturday.
(14) Where to eat Dom Sancho restaurant, an hour away in the hill village of Sortelha, (Rua do Corro, +351 271 388 267) is renowned for its regional food.
(15) The effects of 5-hydroxytryptamine (5-HT) and 2,5-dimethoxy-4-methyl-amphetamine (DOM) on the Ca2+ influx in the ovine uterine artery in late pregnancy have been studied by measuring 45Ca2+ uptake.
(16) The order of potency of these agonists was determined to be DOM greater than 5-HT greater than or equal to alpha-methyl-5-HT much greater than 8-hydroxy-dipropylaminotetralin (8-OH-DPAT) greater than 2-methyl-5-HT greater than 1-(3-chlorophenyl) piperazine (mCPP) greater than m-trifluoromethyl-phenylpiperazine (TFMPP).
(17) The efflux for the initial samples was increased as with the DOM control, but the 6-hydroxydopa pretreatment attuated the DOM-induced efflux for the later samples.
(18) Lord Paul, a Labour donor, rather gave the game away when he said he dropped his non-dom status only when told it stopped him being a lord.
(19) 7.40pm BST If you were wondering why Seagulls no like Eagles and vice versa And why Dom the Glazier put the word 'rival' in quotation marks, here is my colleague Simon Burton's investigation .
(20) The peak PRL response to DOM occurred 15 min after injection.