(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.
Gob
Definition:
(n.) Same as Goaf.
(n.) A little mass or collection; a small quantity; a mouthful.
(n.) The mouth.
Example Sentences:
(1) He questioned the point of spending "huge gobs of money" on the media expansion without addressing issues such as China's human rights record.
(2) It wasn’t yet purely about moronic ugliness, uniformity and gobbing.
(3) The cDNAs encoding two forms of mammalian G(o) alpha were also isolated and designated GoA alpha and GoB alpha.
(4) Both GoA and GoB were found in such cloned cells as PC12, NG108-15, C6, GA-1, G8, and 3T3-L1 cells.
(5) On the other hand, relatively high concentrations of GoB alpha were present in the brain, pituitary gland, adipose tissue, lung, and testis.
(6) Picking up seven years after the last episodes of season three, still stuck in the same rut, Michael's promising to spend more time with his son (George Michael, played by Michael Cera), Gob is begging for money, and Lindsay is trying to find herself while stuck in the world's weirdest marriage with Dr Tobias Funke (David Cross).
(7) These results indicate that the major species of G(o) alpha is encoded by GoA alpha cDNA and G(o)*alpha is encoded by GoB alpha cDNA.
(8) It is possible that GoA alpha and GoB alpha have different functions.
(9) (Incidentally, Jeb is not short for Jebediah, as you might have reasonably assumed – it’s an acronym for John Ellis Bush, like Arrested Development ’s Gob Bluth is an acronym for George Oscar Bluth.)
(10) According to University of California-Berkeley's Debt & Society project , rising higher education spending is in large part driven by factors that have little to do with the quality of instruction or academic resources: schools are pouring gobs of capital into material amenities like student lounges and sports arenas, and this spending in turn raises the cost of the debts schools incur to finance these projects.
(11) These two forms, which we call GoA alpha and GoB alpha, appear to be the products of alternative splicing.
(12) To recognize two forms of G(o) type G proteins, we raised antibodies in rabbits against two peptides with sequences found only in the respective proteins of murine GoA alpha (SNTYEDAAAYIQTQF) and GoB alpha (TEAVAHIQGQYWSK).
(13) ‘owl-light’ (Lancashire) fizmer the whispering sound of wind in reeds or grass (Fenland) grimlins the night hours around midsummer when dusk blends into dawn (Orkney) The word-hoard: Robert Macfarlane on rewilding our language of landscape Read more gruffy ground the surface landscape left behind by lead-mining (Somerset) grumma a mirage caused by mist or haze (Shetland) hob-gob a dangerously choppy sea (Suffolk) muxy of land; sticky, miry, muddy (Exmoor) outshifts the fringes and boundaries of a town (Cambridgeshire) roarie-bummlers fast-moving storm clouds (Scots) snow-bones long thin patches of snow still lying after a thaw, often in dips or stream-cuts (Yorkshire) turn-whol a deep and seething pool where two quick streams meet (Cumbria) zwer the whirring sound made by a covey of partridge taking flight (Exmoor)
(14) OK, you write something, and I’ll see if I feel like drawing something to fit it.” “The cartoonists have shut their gobs?” came one reaction, along with another bottle of Côtes du Rhône.
(15) I told him, proudly proffering my bolus of veg and gob.
(16) Of the brain G proteins, GoA, GoB, and Gi1 contain the same set of three gamma subunits, but Gi2 contains only two of these subunits.
(17) Portia de Rossi plays the third Bluth sibling, Lindsay (who's just as self-centred as Gob, but with a much better wardrobe).
(18) The GoB alpha transcript is expressed at highest levels in brain and testis.
(19) "Each time this claim is raised, we ask the GOB (government of Bahrain) to share its evidence," the US embassy reported in a secret dispatch in August 2008 .
(20) This is gob-smackingly untenable and there should be an uproar about it.