(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.
Lob
Definition:
(n.) A dull, heavy person.
(n.) Something thick and heavy.
(v. t.) To let fall heavily or lazily.
(v. t.) See Cob, v. t.
(n.) The European pollock.
Example Sentences:
(1) But Real are not giving them a chink to exploit so, eventually, Neymar lobs a ball into the box.
(2) There was still time for Saborio to try an audacious lob from distance to steal the game, but Nielsen, who'd looked ponderous in his movements all game, was able to watch this one safely over.
(3) He dictates the next rally and when Murray decides to go for another lob, Dimitrov is on to the ruse and swats a contemptuous smash away to seal the first set that flashed by in the blink of an eye!
(4) But Murray drags it back to deuce, a lob from him and a missed slice from Federer making it so.
(5) Before placing further questions on the notice paper, he lobs this at Bill Shorten.
(6) Italy crashed out, though Fabio Quagliarella’s valedictory lob from distance deep into injury time ensured they at least departed South Africa with a flourish.
(7) "I think his genius is to make people feel comfortable, and then lob in the incendiary."
(8) Before he left, Peter had one more grenade to lob at both of us.
(9) Stoke's Glenn Whelan was sent off for a very silly second yellow card, Hughes found himself banished from the bench for protesting – lobbing his managerial anorak over the dugout roof in disgust en route – and Marc Wilson was also dismissed after conceding a penalty.
(10) First, Álvaro Negredo, once of this parish, came close to lobbing Bravo as the goalkeeper back-pedalled to tip over.
(11) No wonder that Ed Miliband has found it so easy to lob verbal grenades.
(12) He’s not in power yet, so he still gets to blunder around lobbing out daft policies willy-nilly in the hope that one of them will scan.
(13) The assistants – old garage heads who clearly loathed this racket the kids were making – dismissively lobbed a pile of white labels on to the counter.
(14) "So is that hairdo," he lobs back, "but I figure that's your business."
(15) So the idea of a benevolent dictator is not my cup of tea Rand Paul Paul said polls became part of “a self-reinforcing news cycle because of the celebrity nature that goes on, on and on”, though he accepted that voters might “at a superficial level be attracted to bombast, insults, junior high sort of lobbing of verbal bombs that kind of stuff”.
(16) An officer suggested tear gas would quieten them down and a gas canister was lobbed into the transport.
(17) Those guys played some unbelievable lobs and angles.
(18) In another largely Muslim neighbourhood, PK12, families camp out in grass and mud with buckets, carpets, mattresses, discarded rubbish, cooking pots over charcoal fires and a constant fear of lobbed grenades.
(19) She agreed to this interview to discuss Labour's plans to draft landmark legislation on women's safety , but that was before the inquiry into child abuse was announced, and before deputy Labour leader Harriet Harman lobbed a bomb into the party hierarchy, insisting that the Gordon Brown era was marked by sexism and inequality.
(20) Leicester had nothing in response and United had the chances to put a more emphatic slant on the scoreline, with Rashford testing Schmeichel and Mata blowing a one-on-one with a fluffed attempted lob.