(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.
Sob
Definition:
(v. t.) To soak.
(v. i.) To sigh with a sudden heaving of the breast, or with a kind of convulsive motion; to sigh with tears, and with a convulsive drawing in of the breath.
(n.) The act of sobbing; a convulsive sigh, or inspiration of the breath, as in sorrow.
(n.) Any sorrowful cry or sound.
Example Sentences:
(1) "After I saw you there, I just went out and sobbed.
(2) The results suggest that (i) the SOS response of E. coli and the SOB response of B. subtilis are strikingly similar from both a phenotypic and a regulatory standpoint and that RecA and LexA protein analogs exist in B. subtilis, (ii) the Recbs protein is capable of regulating its own production, and (iii) SOS-inducing (RecA-activating) signals are generated in B. subtilis following either DNA damage or the development of physiological competence.
(3) Effects of amygdaloid lesions on the switch-off behavior (SOB) and behavioral changes induced by a delayed reinforcement (DR) for SOB were investigated in 12 cats.
(4) Acts of kindness move Langham to tears, and before long another memory has him sobbing.
(5) He went from minstrel show to blackface, from vaudeville to Broadway before he hit a fabulous prosperity as the most sentimental of all sentimental singers, a poor Russian cantor's son daubed with burnt cork and down on one knee sobbing for the "mammy" he had never known in a south that nobody ever knew.
(6) No one photographs the child with learning difficulty, sobbing as the teaching assistant they worked with for the past three years is booted out.
(7) He is very kind, honest, funny,” she said on Monday, sobbing as she remembered her only child, who had been flying home from Malaysia, where he was studying.
(8) In a televised meeting that has gone viral, the German chancellor rubs the shoulder of a sobbing teenager after telling her she was one of “thousands and thousands” of refugees that her country was unable to help.
(9) Since then, the cursing and sobbing have been plentiful.
(10) "This depressing morning has now got me questioning my pitiful existence," sobs James Dodge.
(11) She is generally a happy person, but in the last few weeks she has been showing signs of deep anxiety, phoning me sobbing with fear.
(12) The 56-year-old held a tissue to her face and sobbed during a five-minute hearing at City of Westminster magistrates court in central London.
(13) Liam Stacey , 21, of Pontypridd, south Wales, sobbed as he was taken away after the failed appeal hearing at Swansea crown court.
(14) The paper's "special investigation", headlined "No ID, no checks … and vouchers for sob stories: the truth behind those shock food bank claims", suggested that claims about the scale of Britain's welfare problems had been exaggerated.
(15) I sobbed for the last 30 pages but not, perhaps, for the reason you'd expect.
(16) Naturally I confronted them about it, halting their child's progress with a foot on the front bumper, loudly berating their crass behaviour while impressed pedestrians looked on, cheering and punching the air and chanting my name until Audi boy's parents fell to the ground, clutching pitifully at my trouser-legs and sobbing for forgiveness.
(17) 4.59pm BST "My fiancee have decided to get married in whichever country wins the World Cup so this game really has me torn," sobs Nate Philipps.
(18) She was followed by several women who must have been relatives or neighbours living nearby; the cries and sobs were so loud they could be heard clearly over the shooting and chanting from the street.
(19) "It's just so depressing this whole situation," sobs Angus Chisholm.
(20) One hand held the corner of the tomb and he sobbed uncontrollably into the other.