(1) To evaluate the in vivo hemodynamics of smaller-sized (21 mm and 23 mm) Medtronic Hall (MH) valves in the aortic position, we measured the maximal pressure gradients (maxPG) at rest and during dobutamine (DOB) administration by continuous-wave Doppler echocardiography in 20 patients with aortic valve replacement.
(2) The second 12 cases were given the same doses of DOB instead of DOA.
(3) The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather high affirmities (pA2 = 7.35, 7.12, and 7.08, respectively) for the 5-HT receptors of the model system.
(4) [82Br]-DOB has been suggested as a potential brain scanning agent for nuclear medicine; 3b would have the advantage over DOB of providing the superior gamma-ray imaging properties of 131I or 123I.
(5) Potassium (K) values were almost constant during infusion of both drugs, but DOB reduced K concentration at the dose of 20 micrograms.kg-1.min-1.
(6) The results were as follows: 1) the effect of catecholamine on Ees prior to brain death was DA = DOB greater than NAD = AD.
(7) The study was aimed at comparing the effects of dobutamine (dob) and dopamine (dop) on isotonic contraction and rhythmicity of isolated guinea-pig papillary muscles (in oxygenated Tyrode at 37 degrees C), by taking into account: 1) the rate of stimulation (50% above the diastolic threshold) at 5 fixed periods: (RR: 1600, 1200, 1000, 800 and 400 ms); 2) 7 log concentrations (logC) of the index amine (from 10(-9) to 10(-3) M).
(8) Our results suggest that even in case of hypothermia, DOB retains a selective inotropic effect with no threat of arrhythmogenicity, and produces stable hemodynamics.
(9) Moreover, a significant correlation exists between drug potencies for (R)-(-)-[77Br]DOB-labeled sites and human hallucinogenic drug potencies (r = 0.89; p less than 0.01).
(10) People can also use their phones to dob in the neighbours.
(11) On the other hand, when CP and freqCP were coded, explanatory variables were AMP% and logAMP% (4.86 > t < 6.95, 0.06 > r2 < 0.09, p < 0.00001), but not the variable used to code the type of treatment (dob versus dop).
(12) In both systems, expression of this single serotonin receptor cDNA led to the appearance of both [3H]DOB and [3H]ketanserin binding sites with properties that matched their binding characteristics in mammalian brain homogenates.
(13) In competition experiments 8-OH-DPAT, TFMPP, mesulergine, DOB, and ICS 205-930 had low affinity for 3H-5HT-labeled 5HT1D sites, indicating that the pharmacology of the 5HT1D site is distinct from previously identified 5HT1A, 5HT1B, 5HT1C, 5HT2, and 5HT3 sites.
(14) Chronic DOB infusion was without effect on CRF concentrations in all hypothalamic and extrahypothalamic brain regions studied.
(15) This effect was apparently associated with down-regulation of the 5-HT2 receptor because high-affinity cortical [3H]DOB and hypothalamic (+-)-[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane binding were decreased at this time as well.
(16) The effects of the 5-HT2-selective agonists 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane (DOB) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on cat platelet aggregation were investigated and compared with those produced by serotonin (5-HT) and a positional isomer of DOB (i.e., isoDOB).
(17) (4) The Dob IgG is relatively resistant to digestion with papain and trypsin; however, it is readily digested with pepsin, although at an unusual site.
(18) In contrast, specific [3H]DOB binding cannot be detected in bovine cortical membranes.
(19) Classical serotonin antagonists, most of which are rather selective for 5-HT2 sites, and 5-HT2-selective antagonists are able to block the stimulus effects of DOM, DOB, and DOI, but not those of 8-OH DPAT or TFMPP.
(20) (3) The Dob heavy chain has three fewer residues of half-cystine than expected in gamma1 chains.
Wrongdoing
Definition:
(n.) Evil or wicked behavior or action.
Example Sentences:
(1) On 18 March 1996, the force agreed, without admitting any wrongdoing by any officer, to pay Tomkins £40,000 compensation, and £70,000 for his legal costs.
(2) On the one hand, putting past wrongdoing behind it helps a company to move on.
(3) The FSA, which was going to be given oversight of hedge funds, will instead be able to demand cooperation from them and from other financial firms it does not regulation during investigations into wrongdoing.
(4) Those wrongdoings taint a whole industry beyond the handful of people and that makes it a huge problem."
(5) Sarkozy, who lost his immunity from prosecution when he failed to secure a second term in office in May, has denied any wrongdoing.
(6) Yentob was eventually cleared of any wrongdoing in October 2004, following an investigation by then BBC chief operating office John Smith.
(7) FBI director: new Hillary Clinton emails show no criminal wrongdoing Read more “Here in Minnesota, you’ve seen first-hand the problems caused with faulty refugee vetting, with very large numbers of Somali refugees coming into your state without your knowledge, without your support or approval,” the Republican nominee told a rally in the solidly Democratic state, two days before the presidential election.
(8) the charge, saying that the Bank simply had "no evidence of wrongdoing" in 2008.
(9) Brandis said nothing in the bill would stop Asio whistleblowers from reporting suspected wrongdoing to the inspector general of intelligence and security.
(10) • Crone and the former NoW editor Colin Myler "misled the committee by answering questions falsely about their knowledge of evidence that other News of the World employees had been involved in phone-hacking and other wrongdoing".
(11) There are allegations of very, very serious dereliction of duty and of wrongdoing by people in the police at the time who were investigating – it is alleged – some of the most grotesque crimes imaginable.” According to Newsnight, the officers involved said they did not know the senior figure who threatened them.
(12) To have a blanket rule of pre-notification really concerns me in terms of the crucial importance for journalists to go out there and investigate wrongdoing," he said.
(13) The standards committee report by a cross-party group of MPs said it "deplored" stings but would "not hesitate to act in such cases if wrongdoing had occurred".
(14) The Senate’s economic references committee accused Asic of missing or ignoring persistent signs of wrongdoing , characterising it as a “timid, hesitant regulator” that was too ready to uncritically accept assurances of a large institution that there were no grounds for intervention.
(15) We encourage people to speak up if they have concerns" #gsk July 24, 2013 12.29pm BST Witty says this investigation is "quite different" to the whistleblower claims the company recently investigated and found no evidence of wrongdoing.
(16) He told the chair, Alexis Jay: “We will never be able to undo the wrongdoing to these children.
(17) As the dust settles and the truth comes out, it’s become totally clear that the only people who engaged in wrongdoing are the criminals behind this fraud, and we’re glad they’re being held accountable.
(18) After international pressure, Sri Lanka conducted its own review of the war that essentially cleared government forces of wrongdoing although it did highlight evidence of possible military abuses that warranted further investigation.
(19) Hastie has been cleared of any wrongdoing in that incident by the ADF.
(20) Moreover, the state-controlled Chinese media have in a series of broadcasts denounced a number of detained “suspects” as members of a crime syndicate engaging in “rights-defence-style troublemaking”, and paraded some of those detained “confessing” to wrongdoing before they have even been publicly indicted.