(n.) A quadruped of the genus Canis, esp. the domestic dog (C. familiaris).
(n.) A mean, worthless fellow; a wretch.
(n.) A fellow; -- used humorously or contemptuously; as, a sly dog; a lazy dog.
(n.) One of the two constellations, Canis Major and Canis Minor, or the Greater Dog and the Lesser Dog. Canis Major contains the Dog Star (Sirius).
(n.) An iron for holding wood in a fireplace; a firedog; an andiron.
(n.) A grappling iron, with a claw or claws, for fastening into wood or other heavy articles, for the purpose of raising or moving them.
(n.) An iron with fangs fastening a log in a saw pit, or on the carriage of a sawmill.
(n.) A piece in machinery acting as a catch or clutch; especially, the carrier of a lathe, also, an adjustable stop to change motion, as in a machine tool.
(v. t.) To hunt or track like a hound; to follow insidiously or indefatigably; to chase with a dog or dogs; to worry, as if by dogs; to hound with importunity.
Example Sentences:
(1) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(2) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(3) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(4) It was shown in experiments on four dogs by the conditioned method that the period of recovery of conditioned activity after one hour ether anaesthesia tested 7 to 7.5 days.
(5) Dialysis of dog plasma against an artificial c.s.f.
(6) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(7) Complete heart block was produced in 20 of 20 dogs.
(8) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
(9) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(10) One hundred and twelve dogs, including twenty C3-deficient dogs, were studied over a period of 6 years.
(11) From the present results it is concluded that secretion of extrapancreatic glucagon increased in response to arginine infusion in the diabetic state, both alloxan diabetic dogs and one-week post-pancreatectomized dogs.
(12) The effect of pO(2) was studied in a further nine dogs.
(13) The effects of tachycardia caused by ectopic right or left ventricular stimulation on ventricular recovery potentials were studied in 30 dogs.
(14) Stimulation with these electrodes were effective for inducing voiding with little residual volume after the recovery of bladder reflexes, 3 weeks after experimental spinal cord injury in the dog.
(15) A neodymium YAG (Nd:YAG) laser was evaluated in a dog ulcer model used in the same manner as is recommended for bleeding patients (power 55 W, divergence angle 4 degrees, with CO2 gas-jet assistance).
(16) Hollywood legend has it that, at the first Academy awards in 1929, Rin Tin Tin the dog won most votes for best actor.
(17) Liver bloodflow remained unchanged in AS dogs, but hepatic alanine uptake nearly tripled (p less than 0.01) and hepatic glucose production increased by 60% (p less than 0.05).
(18) Affected dogs were from ten breeds and their average age was eight years.
(19) Though three of these presumable metabolites could slightly inhibit the binding of [3H]-KW-3049, they were not detected in rat and dog plasma at 0.5 h after oral administration of KW-3049.
(20) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.
Pedigree
Definition:
(n.) A line of ancestors; descent; lineage; genealogy; a register or record of a line of ancestors.
(n.) A record of the lineage or strain of an animal, as of a horse.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Another feature of TWINAN90 is the optional output of a pedigree file which can be read by the quantitative genetics package FISHER.
(4) ESD in conjunction with RB polymorphism would be useful in prenatal and presymptomatic diagnosis, as well as in carrier detection in informative pedigrees.
(5) This paper presents a FORTRAN IV subroutine to calculate inbreeding and kinship coefficients from pedigree information in a diploid population without self-fertilization.
(6) Histologic examination of one patient from each pedigree showed two characteristic findings in corneal epithelium; the previously designated "peculiar substance" in the cells, and the vacuolated homogeneous substance mostly within the cysts.
(7) While Elop has critics who say he did not fix Nokia or much of anything else in his long career in tech, others are likely to point to a pedigree that would also make him the favorite here.
(8) The pedigree analysis provided evidence of both a genetic effect (P less than 0.005) and an effect of increased dietary iron (P less than 0.005) on transferrin saturation and unsaturated iron-binding capacity.
(9) On the other hand, Sillence OI type I segregated with both COL1A1 (17 pedigrees) and COL1A2 (7 pedigrees).
(10) Using 166 pedigrees, reported in nine series available in the literature (including our own), we conclude that balanced insertion cannot entirely explain the familial data, even if we allow for a reduced viability of unbalanced gametes.
(11) To study the genetic influence on serum cholesterol levels and early coronary heart disease, 1,134 individuals were screened from 18 Utah pedigrees.
(12) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(13) Discordant segregation between COL2A1 and the mutant locus was seen in pedigrees with multiple epiphyseal dysplasia, autosomal recessive spondyloepiphyseal dysplasia tarda, hypochondroplasia, pseudoachondroplasia, diaphyseal aclasis, and trichorhinophalangeal syndrome.
(14) Samples originated from eight schizophrenics and 27 relatives belonging to a large pedigree, thus ensuring biological homogeneity.
(15) We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
(16) We have studied five Italian pedigrees segregating schizophrenia using a map of four markers for the chromosomal region 5q11.2-13.3.
(17) Using three markers of chromosome 5, we have studied 28 additional French pedigrees.
(18) The phenotypically and often cytogenetically normal transmitting males in fragile X pedigrees are interpreted not as "nonpenetrant" transmitters of a fully formed fragile X but rather as transmitters of some or all of the factors necessary for TE insertion at Xq27.
(19) The problem has acquired practical importance because of the current international collaboration aimed at constructing a complete human linkage map of DNA markers through the study of three-generation pedigrees.
(20) Linkage analysis with four CMT1A pedigrees mapped the CMT1A gene with respect to two flanking markers (8B10-5 cM[LOD 5.2]-CMT1A-3.5 cM[LOD 5.3]-10E4).