(n.) The territory over which dominion or authority is exerted; the possessions of a sovereign or commonwealth, or the like. Also used figuratively.
(n.) Landed property; estate; especially, the land about the mansion house of a lord, and in his immediate occupancy; demesne.
(n.) Ownership of land; an estate or patrimony which one has in his own right; absolute proprietorship; paramount or sovereign ownership.
Example Sentences:
(1) A former Labour minister, Nicholas Brown, said the public were frightened they "were going to be spied on" and that "illegally obtained" information would find its way to the public domain.
(2) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(3) Therefore, neither of these two regions of the Tat protein appear to be discrete activation domains.
(4) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(5) A domain containing a CA repeat, similar to ones found in other late, cAMP-induced Dictyostelium genes, is required for cAMP-induced and developmental expression.
(6) Blocking the heparin-binding domains of fibronectin inhibited osteoblast attachment by 40-45%, which is complementary to inhibition results previously obtained with the RGDS tetrapeptide.
(7) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(8) The relevant phase diagram shows different macroheterogeneous phases and microstructured domains.
(9) We have examined the in vitro membrane assembly characteristics of a variety of leader peptidase mutants and found that domains required for insertion in vivo are also necessary for insertion in vitro.
(10) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(11) Two lectins, wheat germ agglutinin (WGA) and peanut agglutinin (PNA), were used to compare domains within the interphotoreceptor matrices (IPM) of the cat and monkey, two species where the morphological relationship between the retinal pigment epithelium (RPE) and photoreceptors is distinctly different.
(12) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(13) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
(14) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
(15) In this paper the domain of validity of the unlabelled and labelled minimal models of glucose disappearance is studied.
(16) In vivo labeling with 32Pi showed that plectin was the target for cAMP-independent protein kinases which phosphorylated 18-kDa domains at the end(s) of the molecule.
(17) In contrast, the enzymic domain of the colicin (T2) remained in the aqueous phase and was recovered in a highly active form as a consequence of its dissociation from the immunity protein.
(18) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).
(19) Its features are consistent with observed structural dimensions and the molecular periodicities related to transcription, replication and matrix attachment domains.
(20) The three major RNA domains, as defined by secondary structure, appear to exist as autonomous structural units in three dimensions, for the most part.
Motif
Definition:
(n.) Motive.
Example Sentences:
(1) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(2) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
(3) An additional 14 leader peptides in this collection (all of those that contain an arginine at -10) conform to this motif.
(4) In addition, region III has some structural features similar to a conserved motif found in complement receptor 1, the human C3b receptor.
(5) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(6) The same RNA-protein motif is used, through iron-dependent degradation of transferrin receptor mRNA, to decrease synthesis of the receptor and cellular iron uptake.
(7) Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif.
(8) The three-dimensional solution structure of a zinc finger nucleic acid binding motif has been determined by nuclear magnetic resonance (NMR) spectroscopy.
(9) Sequence comparison programs suggested the presence of domains related to the RNA recognition motif found in other RNA-binding proteins, and deletion analysis revealed that the carboxyl-terminal 195 amino acids of the recombinant PTB was sufficient for specific binding to pre-mRNAs.
(10) Since similar loop conformations form similar "words", the structural sequence facilitates the search for common structural motifs in a family of loops.
(11) A new repetitive DNA region was identified in the non-transcribed spacer of human rDNA, namely a long (4.6 kb) sequence motif (Xbal element) was present in two copies.
(12) X-ray analysis of these crystals will permit direct visualization of the specific structural motifs and chemical features that underlie phospholipase neurotoxicity.
(13) Information about the three-dimensional structure or function of a newly determined protein sequence can be obtained if the protein is found to contain a characterized motif or pattern of residues.
(14) For PPD-specific TCCs, a possible biased usage of V beta 8, as well as possible preferential usage of a CDR3 motif, were found.
(15) This phenomenon was observed by using wheat-germ RNA polymerase II and a series of double-stranded template polymers containing palindromic repeating motifs of 6-16 bp, with regulatory alternating purine and pyrimidine bases such as d[ATA(CG)nC].d[TAT(GC)nG], with n = 1, 3 or 6 referred to as d(GC), d(GC)3 or d(GC)6, respectively.
(16) A sequence between residues 302 and 320 homologous to a metal-binding "finger" motif is therefore not required for origin-specific binding.
(17) In this report, we examined the functional significance of these six motifs for the UL9 protein through the introduction of site-specific mutations resulting in single amino acid substitutions of the most highly conserved residues within each motif.
(18) These sequences have a number of similar motifs at, or immediately following, the end of the coding regions, motifs that may be involved in their S mRNA transcription termination processes.
(19) The TV campaign, created by ad agency Leo Burnett, uses imagery and motifs more closely associated with Christmas than summer.
(20) Interestingly, the helical motif prefers to assemble parallel to the wall, whereas the beta-barrel, predominantly assembles with its principal axis perpendicular to the wall.