(n.) The territory over which dominion or authority is exerted; the possessions of a sovereign or commonwealth, or the like. Also used figuratively.
(n.) Landed property; estate; especially, the land about the mansion house of a lord, and in his immediate occupancy; demesne.
(n.) Ownership of land; an estate or patrimony which one has in his own right; absolute proprietorship; paramount or sovereign ownership.
Example Sentences:
(1) A former Labour minister, Nicholas Brown, said the public were frightened they "were going to be spied on" and that "illegally obtained" information would find its way to the public domain.
(2) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(3) Therefore, neither of these two regions of the Tat protein appear to be discrete activation domains.
(4) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(5) A domain containing a CA repeat, similar to ones found in other late, cAMP-induced Dictyostelium genes, is required for cAMP-induced and developmental expression.
(6) Blocking the heparin-binding domains of fibronectin inhibited osteoblast attachment by 40-45%, which is complementary to inhibition results previously obtained with the RGDS tetrapeptide.
(7) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(8) The relevant phase diagram shows different macroheterogeneous phases and microstructured domains.
(9) We have examined the in vitro membrane assembly characteristics of a variety of leader peptidase mutants and found that domains required for insertion in vivo are also necessary for insertion in vitro.
(10) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(11) Two lectins, wheat germ agglutinin (WGA) and peanut agglutinin (PNA), were used to compare domains within the interphotoreceptor matrices (IPM) of the cat and monkey, two species where the morphological relationship between the retinal pigment epithelium (RPE) and photoreceptors is distinctly different.
(12) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(13) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
(14) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
(15) In this paper the domain of validity of the unlabelled and labelled minimal models of glucose disappearance is studied.
(16) In vivo labeling with 32Pi showed that plectin was the target for cAMP-independent protein kinases which phosphorylated 18-kDa domains at the end(s) of the molecule.
(17) In contrast, the enzymic domain of the colicin (T2) remained in the aqueous phase and was recovered in a highly active form as a consequence of its dissociation from the immunity protein.
(18) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).
(19) Its features are consistent with observed structural dimensions and the molecular periodicities related to transcription, replication and matrix attachment domains.
(20) The three major RNA domains, as defined by secondary structure, appear to exist as autonomous structural units in three dimensions, for the most part.
Smooth
Definition:
(superl.) Having an even surface, or a surface so even that no roughness or points can be perceived by the touch; not rough; as, smooth glass; smooth porcelain.
(superl.) Evenly spread or arranged; sleek; as, smooth hair.
(superl.) Gently flowing; moving equably; not ruffled or obstructed; as, a smooth stream.
(superl.) Flowing or uttered without check, obstruction, or hesitation; not harsh; voluble; even; fluent.
(superl.) Bland; mild; smoothing; fattering.
(superl.) Causing no resistance to a body sliding along its surface; frictionless.
(adv.) Smoothly.
(n.) The act of making smooth; a stroke which smooths.
(n.) That which is smooth; the smooth part of anything.
(a.) To make smooth; to make even on the surface by any means; as, to smooth a board with a plane; to smooth cloth with an iron.
(a.) To free from obstruction; to make easy.
(a.) To free from harshness; to make flowing.
(a.) To palliate; to gloze; as, to smooth over a fault.
(a.) To give a smooth or calm appearance to.
(a.) To ease; to regulate.
(v. i.) To flatter; to use blandishment.
Example Sentences:
(1) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(2) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(3) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(4) Peripheral eosinocytes increased by 10%, and tests for HBsAg, antiHBs, antimitochondrial antibody and anti-smooth muscle antibody were all negative.
(5) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(6) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(7) The Ta loop was a smooth, elongated ellipse in configuration and showed clockwise rotation in all planes, as did the P loop.
(8) This series of tests included tests for pathologic nystagmus, saccades, smooth pursuit, and optokinetic nystagmus, as well as bithermal caloric testing and rotational testing.
(9) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(10) It is concluded that a Na-H antiport system in vascular smooth muscle regulates Na influx rate, contributes to intracellular pH regulation and influences basal levels of Na,K-pump activity.
(11) By 30 min after insemination, the surface of the egg is relatively smooth.
(12) An electrogenic sodium-potassium pump appears to contribute materially to the steady-state potential and to certain of the transient potential responses of vascular smooth muscle.
(13) Distribution patterns of phosphatidylserine and phosphatidylinositol in the smooth muscle as well as in the mucosa were different from those in the liver.
(14) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
(15) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(16) We conclude that once daily doxazosin provides smooth and effective blood pressure control throughout a 24 h post-dose period.
(17) It is suggested that contractile responses to electrical stimulation in isolated sheep urethral smooth muscle are mediated by the sympathetic nervous system, mainly through release of noradrenaline stimulating postjunctional alpha 1-adrenoceptors.
(18) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(19) From the findings of this study the authors recommend wide excision of colorectal smooth-muscle tumours whenever there is a suggestion of malignancy.
(20) All smooth strains of Brucella bear two lipopolysaccharide (LPS) antigens in a ratio that defines the classification of strains in serovars, A (A greater than M), M (M greater than A) and A.M (A = M).