What's the difference between domed and grooved?

Domed


Definition:

  • (a.) Furnished with a dome; shaped like a dome.

Example Sentences:

  • (1) Dome-shaped, fungiform papillae were scattered among these filiform papillae.
  • (2) Ethanol, an agent that increases membrane fluidity, stimulates AC to a much greater extent in homogenates from the 22 month than from the 22 day or 90 day rat bladder dome.
  • (3) And there is plenty of beauty in London - seeing Parliament Square in the snow, the dome of St Paul's rising above the City, the simple perfection of a Georgian terrace or the quietly elegant streets of Mayfair.
  • (4) In the infant and small child, when most repairs are done, nose tip projection is due more to the alar dome component than to the columella.
  • (5) It said it hoped to have a small containment dome in place by late today.
  • (6) Iron Dome receives $176m in annual funding from the US, but the House of Representatives voted in May to double the amount .
  • (7) Steps wind down a rugged rock face to a bedroom, while light floods in from round skylights in the domed ceiling above.
  • (8) Mucosla nodularity of the bladder dome, even without gastrointestinal symptoms, should raise the possibility of regional enteritis.
  • (9) The shadow chancellor told the newspaper the Dome was a mistake and said: "I think you should learn from your mistakes."
  • (10) In both groups clinical and radiological results were better when the cartilage layer at the talar dome was found to be intact at the time of surgical intervention.
  • (11) Histopathological examination of one resected aneurysmal dome confirmed the diagnosis of transmural arteritis secondary to SLE.
  • (12) In addition, the cells receive synapses from numerous nonimmunoreactive terminals including a wide range of different dome-shaped terminals and various scalloped or glomerular terminals.
  • (13) A review of arthroscopic, radiographic, and clinical data of all patients undergoing ankle arthroscopy at our center provided the following diagnoses: talar dome osteochondral fractures, loose bodies, accessory ossicles, talar dome cyst with loose bodies, and chronic synovitis.
  • (14) Pilgrims from all over the world, many weeping and clutching precious mementos or photographs of loved ones, jostle beneath its soaring domes every day.
  • (15) Despite Antarctica's simultaneous warming and cooling phenomena, the second lowest temperatures ever measured on Earth was recorded in July at Dome Argus in the centre of the Antarctic plateau.
  • (16) This domed white building is now a magnet for national expectations, and many wonder whether it will sag under the weight of so much anticipation.
  • (17) The tumor was diffusely hemorrhagic and occupied the dome of the bladder.
  • (18) So here we are in Chester's Mill, a snoozy Maine town about to be rent asunder by the arrival of a mysterious transparent dome, shooming down like a giant jam jar on its coffee shops and car lots and effectively cutting its residents off from the rest of civilisation.
  • (19) Lisa and Brian converted the old wooden schoolhouse six years ago and the design is bright and eclectic, think retro school desks, a funky red kitchen, a clear geodesic dome in the garden for stargazing and chill-out time and a giant chess set on the lawn.
  • (20) Membranous (M) cells within the dome epithelium of ileal Peyer's patches have been shown to provide selective antigen entry for mucosa-associated lymphoid tissue.

Grooved


Definition:

  • (imp. & p. p.) of Groove

Example Sentences:

  • (1) The ligands bind at discrete sites in the minor groove of DNA, and analysis on DNA sequencing gels show pronounced protection at the ligand binding sites, as well as more generalized protection.
  • (2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
  • (3) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
  • (4) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
  • (5) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
  • (6) These results strongly indicate that metallobleomycin binds in the minor groove of B-DNA and that the 2-amino group of guanine adjacent to the 5' side of the cleaved pyrimidine base is one key element of the specific 5' G-C or G-T recognition by the bleomycin-metal complex.
  • (7) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
  • (8) A high intensity of the reactions was observed in certain cells of the neural groove in 24-hours' embryos and in the neural tube of 48-hours' embryos.
  • (9) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
  • (10) In the absence of boxes or grooves, pins markedly enhanced both retention and resistance.
  • (11) Therefore in artificial knee replacement a lateral tilt of the patella sliding groove should not be propagated as 'physiological'.
  • (12) Many antitumor drugs, and many carcinogens, act by binding within the minor groove of double-helical DNA, interfering with both replication and transcription.
  • (13) This instrument, a modification of a corneal trephine, provides a neat, smooth groove of adjustable depth.
  • (14) and the fluid ejected from the ejaculatory groove region (about 0.2 ml.).
  • (15) 3) The significance of minor groove Mtase-DNA interactions to specificity is confirmed.
  • (16) (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor groove of B-DNA, exhibits very little fluorescence in the presence of the ps hairpins but a normal, enhanced emission with the aps oligonucleotides.
  • (17) We have studied the time-resolved and the steady-state fluorescence of the DNA groove binders 4',6-diamidino-2-phenylindole (DAPI) and Hoechst 33258 with the double stranded DNAs poly(dA-dU) and poly(dI-dC) and their halogenated analogs, poly(dA-I5dU) and poly(dI-Br5dC).
  • (18) The complexation-induced chemical shifts and NOE cross peaks in the NOESY map of the 1:1 complex of lexitropsin (1) and d-[CGCAATTGCG]2 reveal that the thiazole ring of the lexitropsin (1) intercalates between dA4.A5 bases and the rest of the ligand resides in the minor groove of the AT rich core of decamer, thus occupying the 5'-AATT sequence on the DNA.
  • (19) All cases had true hypertelorism and a median nasal groove with absence of the nasal tip.
  • (20) Distamycin, Hoechst 33258, and DAPI were used as agents capable of AT-specific binding in the minor groove of DNA while producing no profound long-range distortion of DNA structure.

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