(a.) Twofold; multiplied by two; increased by its equivalent; made twice as large or as much, etc.
(a.) Being in pairs; presenting two of a kind, or two in a set together; coupled.
(a.) Divided into two; acting two parts, one openly and the other secretly; equivocal; deceitful; insincere.
(a.) Having the petals in a flower considerably increased beyond the natural number, usually as the result of cultivation and the expense of the stamens, or stamens and pistils. The white water lily and some other plants have their blossoms naturally double.
(adv.) Twice; doubly.
(a.) To increase by adding an equal number, quantity, length, value, or the like; multiply by two; to double a sum of money; to double a number, or length.
(a.) To make of two thicknesses or folds by turning or bending together in the middle; to fold one part upon another part of; as, to double the leaf of a book, and the like; to clinch, as the fist; -- often followed by up; as, to double up a sheet of paper or cloth.
(a.) To be the double of; to exceed by twofold; to contain or be worth twice as much as.
(a.) To pass around or by; to march or sail round, so as to reverse the direction of motion.
(a.) To unite, as ranks or files, so as to form one from each two.
(v. i.) To be increased to twice the sum, number, quantity, length, or value; to increase or grow to twice as much.
(v. i.) To return upon one's track; to turn and go back over the same ground, or in an opposite direction.
(v. i.) To play tricks; to use sleights; to play false.
(v. i.) To set up a word or words a second time by mistake; to make a doublet.
(n.) Twice as much; twice the number, sum, quantity, length, value, and the like.
(n.) Among compositors, a doublet (see Doublet, 2.); among pressmen, a sheet that is twice pulled, and blurred.
(n.) That which is doubled over or together; a doubling; a plait; a fold.
(n.) A turn or circuit in running to escape pursues; hence, a trick; a shift; an artifice.
(n.) Something precisely equal or counterpart to another; a counterpart. Hence, a wraith.
(n.) A player or singer who prepares to take the part of another player in his absence; a substitute.
(n.) Double beer; strong beer.
(n.) A feast in which the antiphon is doubled, hat is, said twice, before and after the Psalms, instead of only half being said, as in simple feasts.
(n.) A game between two pairs of players; as, a first prize for doubles.
(n.) An old term for a variation, as in Bach's Suites.
Example Sentences:
(1) An unsaturated fatty acid auxotroph of Escherichia coli was grown with a series of cis-octadecenoate isomers in which the location of the double bond varied from positions 3 to 17.
(2) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(3) The use of glucagon in double-contrast studies of the colon has been recommended for various reasons, one of which is to facilitate reflux of barium into the terminal ileum.
(4) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
(5) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(6) To determine the accuracy of double-contrast arthrography in complete rotator cuff tears, we studied 805 patients thought to have a complete rotator cuff tear who had undergone double-contrast shoulder arthrography (DCSA) between 1978 and 1983.
(7) For the detection of this antigen, a double antibody sandwich enzyme-linked immunosorbent assay (ELISA) was employed.
(8) In a double-blind, crossover-designed study, 9 male subjects (age range: 18-25 years) received 25 mg orally, four times per day of either S or an identically-appearing placebo (P) 2 d prior to and during HA.
(9) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(10) Such an approach to investigations into subclinical mastitis is not feasible by means of either single- or double-parameter techniques.
(11) In a randomized double-blind study, 40 patients with coronary heart disease received intravenously either 0.025 mg nitroglycerin or placebo.
(12) In the present study, 125 oesophageal biopsies obtained under direct vision at endoscopy from 22 patients with Barrett's oesophagus were systematically studied using fluorescence and peroxidase antiperoxidase single and double-staining immunocytochemical methods employing highly specific antibodies to localize the following peptide-containing cell types in Barrett's mucosa: gastrin, somatostatin, gastric inhibitory polypeptide, motilin, neurotensin and pancreatic glucagon.
(13) The M 13 specific DNA present in minicells isolated several hours after infection consists of single stranded viral DNA and double stranded replicative forms in nearly equal amounts.
(14) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(16) The effect of ipratropium bromide administered at two dosage levels, 40 and 80 mug, isoproterenol, 150 mug, and placebo using a metered dose inhaler was evaluated in ten adult patients with asthma in a double-blind, crossover study.
(17) PNS at 7 Hz approximately doubled mesenteric venous plasma levels of PGE2 in both 16-week-old SHR and WKY, but PNS did not increase levels of 6-keto-PGF1 alpha in either strain.
(18) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(19) The epidemiological effectiveness of dipyridamol, an interferon-inducing agent used for the prevention of influenza and viral acute respiratory diseases, was tested in 4 epidemiological trials, 3 of them carried out as double blind trials.
(20) Neutral sucrose density sedimentation patterns indicate that neutron-induced double strand-breaks sometimes occur in clusters of more than 100 in the same phage and that the effeciency with which double strand-breaks form is about 50 times that of gamma-induced double strand-breaks.
Substitute
Definition:
(n.) One who, or that which, is substituted or put in the place of another; one who acts for another; that which stands in lieu of something else
(n.) a person who enlists for military service in the place of a conscript or drafted man.
(n.) To put in the place of another person or thing; to exchange.
Example Sentences:
(1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(2) In the clinical trials in which there was complete substitution of fat-modified ruminant foods for conventional ruminant products the fall in serum cholesterol was approximately 10%.
(3) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(4) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(5) The resonance Raman spectra of oxy and deoxy cobalt-substituted hemoglobin (CoHb) are reported.
(6) The most important conclusion of both conferences was that oestrogen substitution can significantly reduce the incidence of fractures in postmenopausal women.
(7) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.
(8) This implies that the epitope(s) of NNA-PLA2 might comprise some substituted residues in the sequence of PLA2 homologues.
(9) The deletions and substitutions appear to occur in separate molecules.
(10) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(11) N-Methoxysulphonamides showed no inhibitory activity, as predicted by the classic work of Krebs on N-substituted inhibitors.
(12) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(13) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(14) Substitutes: Andoni Zubizarreta (Spain), Lajos Detari (Hungary), Dragan Stojkovic (Yugoslavia), Igor Belanov (USSR), Preben Elkjær Larsen (Denmark), Lars Larsson (Sweden), Alexandre Zavarov (USSR).
(15) Lipoprotein concentrations reverted to normal after substitution with thyroxine (T4) until the euthyroid state was reached.
(16) Taken together with our previous studies showing that MDMA substitutes for the phenylisopropylamine stimulant (+)amphetamine, but that neither MDE nor N-OH MDA substitute for (+)amphetamine or for the phenylisopropylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), the present results [i.e., MDMA-stimulus generalization to MDE, N-OH MDA, but not to (+)amphetamine] suggest that 1) MDMA produces effects other than those that may be considered amphetamine-like, and 2) MDE and N-OH MDA are MDMA-like agents with even less of an amphetamine-like component of action than MDMA itself.
(17) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(18) Substitution of DnaK protein with that of the mutant DnaK756 protein blocks lambda P release.
(19) To selectively stain polyanionic macromolecules of growth plate cartilage and to prevent artifacts induced by aqueous fixation, proximal tibial growth plates were excised from rats, slam-frozen, and freeze-substituted in 100% methanol containing the cationic dye Alcian blue.
(20) Plasma drug concentrations, subjective self-ratings, and the digit symbol substitution test (DSST) were evaluated during 24 hours after dosage.