(adv.) Towards the bottom of a hill; as, water runs downhill.
(a.) Declivous; descending; sloping.
(n.) Declivity; descent; slope.
Example Sentences:
(1) Distance running performance is slower on hilly race courses than flat courses even when the start and finish are at the same elevation, resulting in equal amounts of uphill and downhill running.
(2) The Downhills headteacher has said the school has worked hard to improve the quality of teaching.
(3) Like the parental strain, all three types of triple mutant showed moderate rates of downhill lactose transport and were defective in the uphill accumulation of sugars.
(5) Eighty-nine percent of the soleus m. lesions in the downhill runner group and 97% of those in the level runner group were A-band disruptions.
(6) Downhills' latest Ofsted assessment, in September, found that while pupils attained standards that are "well below national expectations … there is a clear trend of improvement".
(7) Physiological strain was greater in uphill than in level or downhill walking (P less than .001).
(8) Net sodium flux across the mucosa was also inhibited under 'downhill' sodium gradient conditions.
(9) The medical profession has gone downhill since the days when abortionists were anathema.
(10) It is proposed here that these amines function by catalyzing the isomerization of 11-cis-retinal thermodynamically downhill to form its all-trans congener.
(11) Despite the innocent verdict, it was essentially downhill from there.
(12) Facebook Twitter Pinterest Even those who’ve never seen a downhill ski race couldn’t help but sympathise with Bode Miller’s agony at missing out on a medal in what will surely be the last Olympic event of his career.
(13) This could be a NaCl pump, a downhill KCl transport mechanism, or a Cl-HCO3 exchange mechanism.
(14) Examination of each case individually suggests that for the majority, brief therapy was useful in stemming a downhill course.
(15) Heart rate and skiing velocities were analyzed over a flat, an uphill, and a downhill section, as well as for the total loop.
(16) Intrathoracic masses as a possible cause of "downhill" varices could not be diagnosed in any of these patients.
(17) In one man, hypomanic symptoms were caused by early HIV encephalopathy; he rapidly developed typical HIV dementia with a marked downhill course.
(18) The subsequent clinical course was progressively downhill.
(19) Lakoff and Johnson wrote out the most pervasive metaphors like this: GOOD IS UP; BAD IS DOWN (“We hit a peak last year, but it’s been downhill ever since”) ARGUMENT IS WAR (“Your claims are indefensible”) IDEAS ARE FOOD (“We shouldn’t spoonfeed our students”) UNDERSTANDING IS SEEING (“Let me point something out to you.
(20) As evidence that energy supplies for this "downhill" process did not become rate limiting after irradiation, we found that carbonylcyanide-m-chlorophenyl-hydrazone did not stimulate ONPG transport of irradiated cells.
Uphill
Definition:
(adv.) Upwards on, or as on, a hillside; as, to walk uphill.
(a.) Ascending; going up; as, an uphill road.
(a.) Attended with labor; difficult; as, uphill work.
Example Sentences:
(1) Distance running performance is slower on hilly race courses than flat courses even when the start and finish are at the same elevation, resulting in equal amounts of uphill and downhill running.
(2) Gillard faces an uphill battle convincing the electorate to back her.
(3) Like the parental strain, all three types of triple mutant showed moderate rates of downhill lactose transport and were defective in the uphill accumulation of sugars.
(4) The ascorbate oxidation was coupled to the uphill Na+ extrusion which was stimulated by CCCP and a penetrating weak base, diethylamine, as well as by valinomycin with or without diethylamine.
(5) Physiological strain was greater in uphill than in level or downhill walking (P less than .001).
(6) Senator Davis is a strong, viable, credible candidate who has raised a substantial amount of money and is the best candidate for Democrats – but it’s still an uphill battle,” he said.
(7) These results indicate that body posture can affect energy expenditure during uphill bicycling through factors unrelated to air resistance.
(8) It functions as a pair of easy-to-use skis for walking uphill, then when it’s time to head down, it quickly transforms into a toboggan for riding safely and enjoyably back to the resort, perhaps even with a few powder turns along the way.
(9) Speaking to the Guardian, Rotheram acknowledged the party faced an uphill struggle in a campaign the Tories are framing as a personality contest between party leaders.
(10) Stonewall does great work but the gay campaign for marriage equality faced an uphill struggle, which was made worse by Stonewall constantly undermining our efforts.
(11) It's going to be uphill for LA here - New York should be thinking: "No stupid penalties, no stupid penalties..." and repeat.
(12) As the transport of cefaclor showed no uphill uptake in the presence of a H+ gradient and its H+ stimulated uptake was small, a H+ gradient-independent carrier-mediated system seems to participate in its transport.
(13) The post-trial injection of 1 ng SP (in 0.5 microliter volume) led to significantly longer latencies in the uphill response.
(14) These are our treaty lands, and we need to protect clean water.’ Photograph: Sam Levin for the Guardian In a recent interview, Archambault acknowledged that the tribes face an uphill battle in the US judicial system: “We always knew that the federal court system was against Indian country.
(15) Heart rate and skiing velocities were analyzed over a flat, an uphill, and a downhill section, as well as for the total loop.
(16) Although efforts to win over Republican hawks appear close to gaining sufficient support in the Senate, the White House continues to face an uphill struggle to persuade enough members of Congress from both parties to authorise its planned strike against Syria in the House.
(17) We have a lot to do in the run up to 2020 – there’s a long road ahead of us and it will be an uphill struggle, but if we can mobilise more people, young and old, and continue to provide a real alternative to austerity and Obsornomics, we might just be in with a fighting chance.
(18) Dyspnoea grade 1 (shortness of breath when walking quickly on the level or uphill) was less well related to age.
(19) Transport of L-glutamic acid into the fission yeast Schizosaccharomyces pombe grown to the early stationary phase and preincubated for 60 min with 1% D-glucose is practically unidirectional and is mediated by a single uphill transport system with a KT of 170 microM and Jmax of 4.8 nmol min-1 (mg dry wt.)-1.
(20) It has been possible to form vesicles from the purified enzyme from Squalus acanthias and to demonstrate the ATP-dependent, ouabain inhibitable, coupled uphill transports of Na+ and K+.